Comparing Imitrex vs Rizatriptan

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Imitrex (sumatriptan)	Rizatriptan	Enter another drug to compare

Imitrex (sumatriptan)

Rizatriptan

Prescription only

Prescribed for Cluster Headaches, Migraine. Imitrex may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Migraine, Headache. Rizatriptan may also be used for purposes not listed in this medication guide.

More about Imitrex (sumatriptan)

More about Rizatriptan

Ratings & Reviews

Imitrex has an average rating of 7.8 out of 10 from a total of 206 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 14% reported a negative effect.

Rizatriptan has an average rating of 8.3 out of 10 from a total of 339 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 12% reported a negative effect.

View all 206 reviews

View all 339 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Nausea (12.6%)
Drowsiness (7.8%)
Headaches (5.3%)
Vomiting (5.3%)
Dizziness (4.9%)
Pain (4.9%)
Burning (3.9%)

View all Imitrex side effects

Drowsiness (11.8%)
Nausea (9.4%)
Tiredness (7.7%)
Dizziness (6.5%)
Sleepy (5.3%)
Pain (3.5%)
Anxiety (2.7%)

View all Rizatriptan side effects

Drug Class

Antimigraine agents

Antimigraine agents

Generic Availability

Lower cost generic approved

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	9 tablet
Strength	50 mg
Per unit^*	$81.94
Cost^*	$737.48

View all Imitrex prices

Quantity	12 each
Strength	10 mg
Per unit^*	$1.52 - $10.56
Cost^*	$18.19 - $126.67

View all Rizatriptan prices

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Dosage Forms

Oral tablet
Subcutaneous solution

Oral tablet
Oral tablet, disintegrating

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

6 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 101 drugs are known to interact with Imitrex:

70 major drug interactions (281 brand and generic names)
31 moderate drug interactions (169 brand and generic names)

A total of 156 drugs are known to interact with Rizatriptan:

71 major drug interactions (293 brand and generic names)
30 moderate drug interactions (164 brand and generic names)
55 minor drug interactions (343 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

June 01, 1995

June 29, 1998

WADA Class View classifications

N/A

More Information

Patient Resources

Imitrex uses

Rizatriptan uses

Professional Resources

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Imitrex vs Rizatriptan

See also:

Ubrelvy

Nurtec ODT

Qulipta

Emgality

Deltasone

Indocin

Rayos

Cafergot

Dihydroergotamine

Galcanezumab

Further information

Comparing Imitrex vs Rizatriptan

See also:

Further information

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