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Imitrex and Pain: What Users Say

Pain: mentioned by 10 users (4.9%)

Based on user experiences from 206 Imitrex reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 12.6%
drowsiness 7.8%
headaches 5.3%
vomiting 5.3%
dizziness 4.9%
pain 4.9%
burning 3.9%
chest pain 3.9%
fatigue 3.4%
hot flashes 3.4%

Reviews for Imitrex

Commonly mentioned side effects
  • TAa...
  • Taken for less than 1 month
  • July 3, 2019

For Migraine "Worst experience of my life! Started feeling jaw pain, shoulder pain, nausea, heart racing, and the worst was a tingly/numbing sensation in my arms and legs. I felt like I was going to die. Did not help my migraine at all. This should be taken off the market."

1 / 10
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100 Report
  • TAa...
  • Taken for less than 1 month
  • July 3, 2019

For Migraine "Worst experience of my life! Started feeling jaw pain, shoulder pain, nausea, heart racing, and the worst was a tingly/numbing sensation in my arms and legs. I felt like I was going to die. Did not help my migraine at all. This should be taken off the market."

1 / 10
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100 Report
  • Anonymous
  • June 12, 2009

For Migraine "I'm a 3-4 migraines per week person. When I first tried Imitrex, I thought I had found my own personal miracle. Even on days that I didn't have a full-blown migraine, I would still have pain, and this was the first time I felt completely pain-free in years. Unfortunately, the honeymoon wore off after about 8 months. I used Imitrex quite frequently during that time and had wonderful results, even though sometimes I had to take two pills to really do the job. But after eight months, two pills weren't doing the job, my headache was still lingering."

5 / 10
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16 Report

Frequently asked questions

  • ste...
  • Taken for 2 to 5 years
  • April 12, 2017

For Migraine "I avoid taking Imitrex if I can because I experience so many side effects from it. I get jaw and shoulder pain/stiffness, pain in the back of my neck and scalp, headaches, drowsiness, and I just generally feel weird and awful after taking it. After 2 hours or so, my migraine goes away and the awful-ness of the Imitrex lessens, so that is why I do take it occasionally. Every time I take it, I'm reminded of how badly I need to find something else."

6 / 10
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11 Report
  • ste...
  • Taken for 2 to 5 years
  • April 12, 2017

For Migraine "I avoid taking Imitrex if I can because I experience so many side effects from it. I get jaw and shoulder pain/stiffness, pain in the back of my neck and scalp, headaches, drowsiness, and I just generally feel weird and awful after taking it. After 2 hours or so, my migraine goes away and the awful-ness of the Imitrex lessens, so that is why I do take it occasionally. Every time I take it, I'm reminded of how badly I need to find something else."

6 / 10
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11 Report

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  • Dan...
  • Taken for less than 1 month
  • November 13, 2018

For Migraine "This was the first time I took it, got a migraine 2 days in a row after getting auras, worked for me, I still had pain but very, very minimal compared to the past. I haven't had a migraine in 19 months before this."

10 / 10
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  • lan...
  • Taken for less than 1 month
  • March 2, 2021

For Migraine "I took this for the first time nearly 20 years ago, and it caused so much pain I passed out and didn't wake up for 18 hours. Last year, my doctor prescribed it to me again, thinking I may have grown out of it. So, a couple of days later, I was having a bad migraine, and I took it. After just a few minutes, my skull started feeling like it was on fire. The pain was so intense I immediately started pacing, not knowing what to do. I ended up laying down while my wife brought me ice packs, and I eventually passed out just as I did 20 years ago."

1 / 10
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More FAQ

  • Anonymous
  • January 6, 2010

For Migraine "Imitrex pills worked for me for a few years, but then it stopped being as effective, and I had to take 2... Then that stopped working, so I tried Imitrex stat dose (the injections), and they work wonders. They hurt a lot, but the pain in my leg after I give it to myself is far less horrible than the migraine pain! I give myself the shot and lie down for about 15 minutes, and I'm fine! Maybe a little pain, but I feel much better! I'm also on Timolol, Neurontin, and Cymbalta, and my migraines have reduced in number, and then this helps when I get them. And the shot works after you've had the migraine for a while - you don't have to take it at the first sign to get relief."

10 / 10
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  • liz...
  • March 2, 2011

For Migraine "I'm 54 years old and have used Imitrex for almost 20 years. No side effects except leg pain for about 24 hours, as if I overused in a workout. Was on 100 mg tabs for a long time, with 3 mg self-injections as necessary. Now just taking 50 mg as I get fewer and less intense headaches now. This medicine is worth trying, but ask for an EKG first if the doctor doesn't order it, this can help check for heart okay first."

10 / 10
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  • jpd...
  • November 10, 2009

For Migraine "Thank God for Imitrex. The first tablet I took stopped the headache and didn't have any side effects the first time. The next time I took it, I felt shaky. The only side effect that I get from Imitrex is jaw pain. But at least my migraines are no longer in my back. Just make sure that if you are needing two 100 mg tablets a day for several days in a row and you still aren't getting relief, consider a preventive or have a backup. I don't have nearly as many headaches anymore."

6 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.