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RizaFilm

Pronunciation: ri-zah film
Generic name: rizatriptan
Dosage form: oral film
Drug class: Antimigraine agents

Medically reviewed by Judith Stewart, BPharm. Last updated on Oct 26, 2023.

What is RizaFilm?

RizaFilm is a prescription medicine used for the treatment of migraine.

RizaFilm is an oral film that contains the drug rizatriptan, which belongs to the class of medicines called serotonin receptor agonists (triptans).

Rizatriptan works by binding to serotonin (5-hydroxytryptamine or 5-HT) receptors in the brain to reduce vasodilation and inflammation of the blood vessels associated with migraine.

Rizatriptan was first approved by the FDA in oral tablet form under the brand name Maxalt in 1998.

What is RizaFilm used to treat?

RizaFilm is used to treat migraine attacks with or without aura in adults and in children 12 to 17 years of age who weigh 40 kg or more.

Migraine is a type of headache characterized by recurrent attacks of moderate to severe throbbing and pulsating pain on one side of the head. At the onset of migraine, the trigeminal nerve releases a chemical called calcitonin gene-related peptide (CGRP) which relaxes the blood vessel walls causing vasodilation.

RizaFilm works to reduce the vasodilation in migraine by constricting the blood vessels.

RizaFilm is not to be used to prevent migraine attacks.

It is not known if this medicine is safe and effective for the treatment of cluster headaches.

It is not known if this medicine is safe and effective in children under 12 years of age and who weigh less than 40 kg.

Who should not take RizaFilm?

Do not take RizaFilm if you:

Talk to your doctor before taking this medicine if you have any of the conditions listed above or if you are not sure if you take any of these medicines.

Before you take RizaFilm

Before you take RizaFilm, tell your doctor about all of your medical conditions, including if you:

Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant. It is not known if this medicine will harm your unborn baby.

If you become pregnant while taking RizaFilm, talk to your healthcare provider.

Breastfeeding

Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if this medicine passes into your breast milk.

Talk to your healthcare provider about the best way to feed your baby if you take RizaFilm.

What other drugs will affect RizaFilm?

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

RizaFilm and other medicines may affect each other causing side effects. It may affect the way other medicines work, and vice versa.

Especially tell your doctor if you take:

 Ask your doctor or pharmacist for a list of these medicines, if you are not sure.

Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

Ubrelvy, ibuprofen, amitriptyline, diclofenac, propranolol, topiramate, celecoxib

How should I take RizaFilm?

Take RizaFilm exactly as your doctor tells you to take it.

Your doctor will tell you how much to take and when to take it.

Leave the oral film in the aluminum pouch it comes in until you are ready to take it.

When you are ready to take it, remove the oral film from the aluminum pouch by folding the pouch on the dotted line and tearing it open at the tear notch.

Place the oral film on the tongue. The oral film will disintegrate in about 2 minutes and can be swallowed with saliva. No liquid is required to take the oral film.

If your headache comes back after your first dose:

If you take too much or overdose, call your doctor or go to the nearest hospital emergency room right away.

Dosing information

Usual Adult Dose for Migraine

10 mg single dose; separate repeat doses by at least two hours; maximum cumulative dosage in a 24-hour period is 30 mg

Use: for the acute treatment of migraine with or without aura in adults.

Usual Pediatric Dose for Migraine

10 mg single dose

Use: for the acute treatment of migraine with or without aura in pediatric patients 12 to 17 years of age weighing 40 kg or more.

What should I avoid while taking RizaFilm?

RizaFilm may cause dizziness, weakness, or fainting. If you have these symptoms, do not drive a car, use machinery, or do anything that needs you to be alert.

RizaFilm side effects

RizaFilm may cause serious side effects. Call your doctor or go to the nearest hospital emergency room right away if you think you are having any of the serious side effects including:

The most common side effects in adults include:

Adverse reactions in children are expected to be similar to those in adults.

Tell your doctor if you have any side effect that bothers you or that does not go away.

If you take RizaFilm too often, this may result in you getting chronic (lasting a long time) headaches. In such cases, you should contact your doctor, as you may have to stop taking RizaFilm.

These are not all the possible side effects. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store RizaFilm?

Store RizaFilm oral film at room temperature between 68°F to 77°F (20°C to 25°C).

Keep the oral film in its aluminum pouch until you are ready to take it.

Keep all medicines out of the reach of children and pets.

General information about the safe and effective use of RizaFilm.

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use this medicine for a condition for which it was not prescribed. Do not give it to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or doctor for information about that is written for health professionals. You can ask your pharmacist or doctor for information that is written for health professionals.

What are the ingredients in RizaFilm?

Active ingredient: rizatriptan.
Inactive ingredients: ammonium glycyrrhizate, butylated hydroxytoluene, copovidone, cupric chloride, ethylcellulose, FD&C Blue No. 1, hydroxypropyl cellulose, isopropyl alcohol, levomenthol, methyl ethyl ketone, sodium acetate, sucralose, titanium dioxide, and triacetin.

Popular FAQ

How often can you take Maxalt?

For adults: if your headache returns after your first Maxalt (rizatriptan) dose, you can take a second dose at least 2 hours after the first dose. In children 6 to 17 years of age: it is not known if taking more than one dose of Maxalt in 24 hours is safe and effective. The maximum dose of Maxalt or Maxalt-MLT an adult should take in any 24-hour period is 30 milligrams (mg). For example, do not take more than three 10-mg Maxalt tablets in any 24-hour period. Continue reading

How long does it take for Maxalt to work?

Maxat and Maxalt-MLT will start to work for a migraine headache within 30 minutes for some patients. By 2 hours, there is a 60% to 70% chance of having a headache response (no pain or mild pain) in patients being treated with Maxalt or Maxalt-MLT. Continue reading

Does Maxalt have caffeine in it?

No, Maxalt does not contain caffeine. Maxalt contains rizatriptan benzoate, a medicine in a class of prescription drugs known as “triptans” used for migraine headaches. Continue reading

More FAQ

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.