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Rizatriptan use while Breastfeeding

Drugs containing Rizatriptan: Maxalt, Maxalt-MLT

Medically reviewed by Drugs.com. Last updated on Sep 25, 2020.

Rizatriptan Levels and Effects while Breastfeeding

Summary of Use during Lactation

Preliminary evidence indicates that rizatriptan levels in breastmilk are low. Amounts ingested by the infant are small and unlikely to affect the nursing infant, especially if the infant is older than 2 months.

Drug Levels

Maternal Levels. Five women who were at least 1 month postpartum using rizatriptan to treat migraine provided milk samples at intervals over a 24-hour period after a single dose. The authors estimated the weight-adjusted infant dosage to be 0.9% (range 0.3 to 1.4%).[1]

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Eletriptan, Sumatriptan, Zolmitriptan

References

1.
Amundsen S, Nordeng H, Fuskev├ąg OM, et al. Transfer of triptans into human breast milk and estimation of infant drug exposure through breastfeeding. Reprod Toxicol. 2019;88:141. [CrossRef]

Substance Identification

Substance Name

Rizatriptan

CAS Registry Number

144034-80-0

Drug Class

Breast Feeding

Lactation

Serotonin Receptor Agonists

Serotonin 5-HT1 Receptor Agonists

Triptans

Vasoconstrictor Agents

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Further information

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