Eletriptan use while Breastfeeding

Drugs containing Eletriptan: Relpax

Medically reviewed by Drugs.com. Last updated on Feb 14, 2019.

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Eletriptan Levels and Effects while Breastfeeding

Summary of Use during Lactation

Limited information indicates that a maternal dose of eletriptan up to 80 mg daily produce low levels in milk and would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months.

Drug Levels

Maternal Levels. Eight lactating women who were at least 1 month postpartum were given a single 80 mg oral dose of eletriptan. An average of 12.9 mcg was excreted in the 24 hours after the dose. At 24 hours, breastmilk levels averaged 1.7 mcg/L. The half-life in milk of eletriptan was 3.6 hours.[1] Although the active metabolite was not measured in breastmilk and it has a longer half-life than eletriptan, but its serotonin agonist activity is only about 10% that of eletriptan.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Sumatriptan

References

1. FDA Center for Drug Evaluation and Research. NDA 21-016. Clinical pharmacology and biopharmaceutics reviews. http://www.fda.gov/cder/foi/nda/2002/21016_Relpax_BioPharmr.pdf. 2002;8-9. Accessed 11/3/03.

Eletriptan Identification

Substance Name

Eletriptan

CAS Registry Number

177834-92-3

Drug Class

Breast Feeding

Lactation

Serotonin Agonists

Vasoconstrictor Agents

Serotonin 5-HT1 Receptor Agonists

Triptans

Administrative Information

LactMed Record Number

350

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Further information

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