Comparing Imitrex vs Nurtec ODT

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Imitrex (sumatriptan)	Nurtec ODT (rimegepant)	Enter another drug to compare

Imitrex (sumatriptan)

Nurtec ODT (rimegepant)

Prescription only

Prescribed for Cluster Headaches, Migraine. Imitrex may also be used for purposes not listed in this medication guide.

Prescription only

Nurtec ODT may be placed onto or under the tongue to treat the symptoms of migraine in adults, and it may also be used to prevent episodic migraine when taken every second day. Nurtec ODT works by... View more

More about Imitrex (sumatriptan)

More about Nurtec ODT (rimegepant)

Ratings & Reviews

Imitrex has an average rating of 7.8 out of 10 from a total of 206 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 14% reported a negative effect.

Nurtec ODT has an average rating of 6.4 out of 10 from a total of 334 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 29% reported a negative effect.

View all 206 reviews

View all 334 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Nausea (12.6%)
Drowsiness (7.8%)
Headaches (5.3%)
Vomiting (5.3%)
Dizziness (4.9%)
Pain (4.9%)
Burning (3.9%)

View all Imitrex side effects

Nausea (18.9%)
Dizziness (4.5%)
Headaches (3.9%)
Tiredness (3.9%)
Migraine (3.3%)
Upset stomach (3.0%)
Vomiting (3.0%)

View all Nurtec ODT side effects

Drug Class

Antimigraine agents

CGRP inhibitors

Generic Availability

Lower cost generic approved

No lower cost generic approved

Pricing and Coupons * Prices are without insurance

Quantity	9 tablet
Strength	50 mg
Per unit^*	$81.94
Cost^*	$737.48

View all Imitrex prices

Quantity	8 tablet, disintegrating
Strength	75 mg
Per unit^*	$138.56
Cost^*	$1,108.47

View all Nurtec ODT prices

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Dosage Forms

Oral tablet
Subcutaneous solution

Oral tablet, disintegrating

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

6 hours

11 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.

Drug Interactions

A total of 102 drugs are known to interact with Imitrex:

70 major drug interactions (282 brand and generic names)
32 moderate drug interactions (172 brand and generic names)

A total of 171 drugs are known to interact with Nurtec ODT:

57 major drug interactions (174 brand and generic names)
113 moderate drug interactions (320 brand and generic names)
1 minor drug interactions (2 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

If you are receiving therapy with rimegepant you may want to avoid the regular consumption of large... View more

Disease Interactions

First Approval Date

June 01, 1995

February 27, 2020

WADA Class View classifications

N/A

More Information

Patient Resources

Imitrex uses

Nurtec ODT uses

Professional Resources

Prescribing information

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Imitrex vs Nurtec ODT

See also:

Ubrelvy

Nurtec ODT

Qulipta

Emgality

Indocin

Deltasone

Rayos

Sterapred

Galcanezumab

Dihydroergotamine

Further information

Comparing Imitrex vs Nurtec ODT

See also:

Further information

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