Comparing Ibrutinib vs Rituximab

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Ibrutinib	Rituximab	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Ibrutinib	Rituximab	Enter another drug to compare
Prescription only Ibrutinib is an oral tablet that may be taken once daily to treat certain types of cancers in adults or to treat chronic Graft Versus Host disease in adults and children older than 1 year. It works... View more	Prescription only Rituximab (brand name Rituxan) is a CD20 monoclonal antibody that causes B-cells to self-destruct or disintegrate and may be used to treat Non-Hodgkin's lymphoma (NHL), chronic lymphocytic leukemia... View more	Related suggestions Chronic Lymphocytic Leukemia Imbruvica Rituxan Calquence Acalabrutinib Gazyva Brukinsa Popular comparisons Ibrutinib vs tacrolimus Ibrutinib vs Rituxan Ibrutinib vs Calquence Ibrutinib vs Imbruvica
More about Ibrutinib	More about Rituximab
Ratings & Reviews
Ibrutinib has an average rating of 6.9 out of 10 from a total of 87 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 26% reported a negative effect.	Rituximab has an average rating of 7.7 out of 10 from a total of 175 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 14% reported a negative effect.
View all 87 reviews	View all 175 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
Diarrhea (11.5%) Fatigue (8.0%) Heart palpitations (8.0%) High blood pressure (6.9%) Back pain (4.6%) Mouth sores (4.6%) Cramps (3.4%) View all Ibrutinib side effects	Allergic reaction (7.4%) Headaches (6.9%) Itching (6.9%) Nausea (5.7%) Tiredness (5.7%) Dizziness (5.1%) Fatigue (5.1%) View all Rituximab side effects
Drug Class
BTK inhibitors	Antirheumatics CD20 monoclonal antibodies
Generic Availability
N/A	N/A
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
N/A	N/A
Brand Names
Imbruvica	Riabni, Rituxan, Ruxience, Truxima
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
6 hours	59.8 hours
CSA Schedule ¹ View glossary of CSA terms
N Not a controlled drug Is not subject to the Controlled Substances Act.	N Not a controlled drug Is not subject to the Controlled Substances Act.
Pregnancy Category
D Category D Positive evidence of risk See the full pregnancy warnings document.	C Category C Risk cannot be ruled out See the full pregnancy warnings document.
Drug Interactions
A total of 506 drugs are known to interact with Ibrutinib: 198 major drug interactions (699 brand and generic names) 302 moderate drug interactions (910 brand and generic names) 6 minor drug interactions (12 brand and generic names)	A total of 196 drugs are known to interact with Rituximab: 53 major drug interactions (147 brand and generic names) 138 moderate drug interactions (387 brand and generic names) 5 minor drug interactions (20 brand and generic names)
Alcohol/Food/Lifestyle Interactions
Ibrutinib should be taken once daily at approximately the same time everyday. Do not consume... View more	No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease Interactions
Arrhythmias Bleeding Cytopenia Hepatic impairment Hypertension Infections Renal impairment Tumor lysis syndrome	Autoimmune diseases Cardiac dysfunction Hepatitis B TLS Bone marrow suppression Infections Renal impairment
First Approval Date
November 13, 2013	N/A
WADA Class View classifications
N/A	N/A
More Information
Side effects Drug interactions Dosage Pregnancy warnings Breastfeeding warnings Support group En español	Side effects Drug interactions Dosage Pregnancy warnings Breastfeeding warnings Support group En español
Patient Resources
Ibrutinib uses	Rituximab uses Advanced reading
Professional Resources
Monograph (AHFS) Prescribing information	Monograph (AHFS) Prescribing information
Related Treatment Guide
Graft Versus Host Disease Waldenström Macroglobulinemia Chronic Lymphocytic Leukemia	Follicular Lymphoma Diffuse Large B-Cell Lymphoma Granulomatosis with Polyangiitis Chronic Lymphocytic Leukemia Non-Hodgkin's Lymphoma Bullous Pemphigoid Evan's Syndrome Focal Segmental Glomerulosclerosis Immune Thrombocytopenia Immunoglobulin G4-Related Disease Mantle Cell Lymphoma Microscopic Polyangiitis Pemphigus Vulgaris Rheumatoid Arthritis Thrombocytopenia show all

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

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Comparing Ibrutinib vs Rituximab

See also:

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Comparing Ibrutinib vs Rituximab

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