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Ibrutinib and Cramps: What Users Say

Brand names: Imbruvica

Cramps: mentioned by 3 users (3.6%)

Based on user experiences from 84 Ibrutinib reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 11.9%
fatigue 8.3%
heart palpitations 8.3%
high blood pressure 7.1%
back pain 4.8%
mouth sores 4.8%
cramps 3.6%
dizziness 3.6%
nerve pain 3.6%
shortness of breath 3.6%

Reviews for Ibrutinib

  • Mfi...
  • January 9, 2018

Ibrutinib for Graft Versus Host Disease "About me: AML, stem cell transplant survivor with GVHD. How Imbruvica helped: I started Imbruvica in 4/17. Prior to taking it, I was completely debilitated. After 4 full months on the drug, I noted marked improvement. Now I am able to walk, light lifting, and carry out regular activity with much less fatigue and pain. My skin GVHD is not showing any symptoms. It's been a godsend! Side effects: I noticed cramping at about 5 months and back and joint pain at 8 months. The cramping became severe, however, it is managed well with tonic water. The pain is extreme at times - but so far outweighs the GVHD symptoms."

8 / 10
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7 Report
  • GGL...
  • Taken for 1 to 6 months
  • December 7, 2018

Ibrutinib for Graft Versus Host Disease "Started Ibrutinib (Imbruvica) on 10/22/2018 (7 wks ago) for cGVHD (Chronic graft-versus-host disease) arising from stem cell transplantation (SCT) (matching female sibling) in 2014 to treat Mantle cell lymphoma (MCL). cGVHD (skin, eyes, mouth & subcutaneous tissue) resistant to frontline treatment (Mycophenolate & prednisone - ave dose 20mg). Experienced quite severe diarrhea after 2 days. Resolved after 5 weeks after taking loperamide, which is no longer required. Also experienced increased fatigue and maybe slightly more cramping (was already getting some cramps which is common for cGVHD). Immunoglobulin levels have dropped will require an infusion. Some early signs that skin symptoms, i.e., scleroderma, might be reducing. However, too early to tell effectiveness, suspect it will be another 30-60 days before starting to see if it will have an impact."

7 / 10
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1 Report
  • CLL...
  • Taken for 1 to 6 months
  • July 23, 2014

For Chronic Lymphocytic Leukemia "Side effects for me: muscle spasms, mouth ulcers, diarrhea, fatigue, dizziness, itchy skin, sore throat, cramps, insomnia, sun sensitivity, and drowsiness."

7 / 10
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31 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.