Ibrutinib Alternatives Compared
| Ibrutinib | Imbruvica | Rituximab |
|
|---|
| Ibrutinib | Imbruvica (ibrutinib) | Rituximab |
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
Prescription only
Prescribed for Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Non-Hodgkin's Lymphoma, Waldenström Macroglobulinemia, Graft-versus-host disease, Lymphoma. ibrutinib may also be used for purposes... View more |
Prescription only
Imbruvica is an oral tablet that may be taken once daily to treat certain types of cancers in adults or to treat chronic Graft Versus Host disease in adults and children older than 1 year. It works... View more |
Prescription only
Rituximab is a CD20 monoclonal antibody that causes B-cells to self-destruct or disintegrate and may be used to treat Non-Hodgkin's lymphoma (NHL), chronic lymphocytic leukemia (CLL), rheumatoid... View more |
Related suggestions Non-Hodgkin's Lymphoma
Mantle Cell Lymphoma
Popular comparisons
|
|||||||
| More about Ibrutinib | More about Imbruvica (ibrutinib) | More about Rituximab | ||||||||
| Generic Status | ||||||||||
|
No lower-cost generic available |
No lower-cost generic available |
No lower-cost generic available |
||||||||
| Ratings & Reviews | ||||||||||
|
Ibrutinib has an average rating of 5.9 out of 10 from a total of 58 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 39% reported a negative effect. |
Imbruvica has an average rating of 5.4 out of 10 from a total of 45 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 44% reported a negative effect. |
Rituximab has an average rating of 7.5 out of 10 from a total of 114 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 16% reported a negative effect. |
||||||||
| Drug Class | ||||||||||
| Side Effects | ||||||||||
|
Commonly reported side effects include:
See also: ibrutinib side effects in more detail. |
Common side effects include:
See also: Imbruvica side effects in more detail. |
See also: rituximab side effects in more detail. |
||||||||
| Pricing and Coupons * Prices are without insurance | ||||||||||
|
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Imbruvica prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
||||||||
| Dosage Form(s) Available | ||||||||||
|
N/A |
|
N/A |
||||||||
| Brand Names | ||||||||||
| Imbruvica |
N/A |
Riabni, Rituxan, Ruxience, Truxima | ||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||
|
6 hours |
6 hours |
59.8 hours |
||||||||
| CSA Schedule ** View glossary of terms | ||||||||||
|
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
||||||||
| Pregnancy Category | ||||||||||
|
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
||||||||
| Drug Interactions | ||||||||||
|
A total of 414 drugs are known to interact with ibrutinib:
|
A total of 414 drugs are known to interact with Imbruvica:
|
A total of 149 drugs are known to interact with rituximab:
|
||||||||
| Alcohol/Food/Lifestyle Interactions | ||||||||||
|
|
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
||||||||
| Disease Interactions | ||||||||||
| First Approval Date | ||||||||||
|
November 13, 2013 |
November 13, 2013 |
N/A |
||||||||
| WADA Class View World Anti-Doping Agency classifications. | ||||||||||
|
N/A |
N/A |
N/A |
||||||||
| More Information | ||||||||||
| Patient resources | ||||||||||
| Professional Resources | ||||||||||
| Related Treatment Guide | ||||||||||
|
||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.