Glucophage Alternatives Compared
| Glucophage (metformin) | Rybelsus (semaglutide) | Mounjaro (tirzepatide) |
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| Glucophage (metformin) | Rybelsus (semaglutide) | Mounjaro (tirzepatide) |
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Prescription only
Prescribed for Type 2 Diabetes. Glucophage may also be used for purposes not listed in this medication guide. |
Prescription only
Rybelsus (semaglutide) is an oral medicine that can be used as a first-line medication to improve blood sugar control in adults over the age of 18 with type 2 diabetes. It works by mimicking the... View more |
Prescription only
Prescribed for Weight Loss (Obesity/Overweight), Type 2 Diabetes. Mounjaro may also be used for purposes not listed in this medication guide. |
Related suggestions Type 2 Diabetes
Popular comparisons
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| More about Glucophage (metformin) | More about Rybelsus (semaglutide) | More about Mounjaro (tirzepatide) | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Glucophage has an average rating of 6.9 out of 10 from a total of 39 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 23% reported a negative effect. |
Rybelsus has an average rating of 6.4 out of 10 from a total of 313 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 22% reported a negative effect. |
Mounjaro has an average rating of 8.5 out of 10 from a total of 1452 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 6% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
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View all Glucophage side effects |
View all Rybelsus side effects |
View all Mounjaro side effects |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Rybelsus prices |
View all Mounjaro prices |
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| Dosage Forms | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
| Other metformin brands include: Glumetza | Other semaglutide brands include: Ozempic, Wegovy | Other tirzepatide brands include: Zepbound | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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4.5 hours |
168 hours |
120 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 381 drugs are known to interact with Glucophage:
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A total of 275 drugs are known to interact with Rybelsus:
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A total of 416 drugs are known to interact with Mounjaro:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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| First Approval Date | ||||||||||||||||||
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March 03, 1995 |
September 20, 2019 |
N/A |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.