Comparing Fluticasone / Salmeterol vs Tiotropium

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Fluticasone / salmeterol	Tiotropium	Enter another drug to compare

Fluticasone / salmeterol

Tiotropium

Prescription only

Prescribed for Asthma - Maintenance, COPD - Maintenance, Asthma, COPD, COPD - Acute. Fluticasone / salmeterol may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for COPD - Maintenance, Asthma - Maintenance, COPD - Acute, COPD. Tiotropium may also be used for purposes not listed in this medication guide.

More about Fluticasone / salmeterol

More about Tiotropium

Ratings & Reviews

Fluticasone / salmeterol has an average rating of 4.9 out of 10 from a total of 274 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 49% reported a negative effect.

Tiotropium has an average rating of 5.9 out of 10 from a total of 158 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 30% reported a negative effect.

View all 274 reviews

View all 158 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Shortness of breath (14.6%)
Cough (11.3%)
Sore throat (8.8%)
Chest pain (5.5%)
Headaches (5.5%)
Thrush (5.1%)
Increased heart rate (4.0%)

View all Fluticasone / salmeterol side effects

Dry mouth (11.4%)
Cough (7.6%)
Sore throat (6.3%)
Blurred vision (5.1%)
Insomnia (4.4%)
Chest pain (3.8%)
Cramps (3.8%)

View all Tiotropium side effects

Drug Class

Bronchodilator combinations

Anticholinergic bronchodilators

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	60 powder
Strength	100 mcg-50 mcg/inh
Per unit^*	$1.85
Cost^*	$111.20

View all Fluticasone / salmeterol prices

Quantity	30 each
Strength	18 mcg
Per unit^*	$13.24
Cost^*	$397.09

View all Tiotropium prices

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Dosage Forms

Inhalation aerosol
Inhalation powder

Inhalation capsule

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

12.6 hours

144 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 471 drugs are known to interact with Fluticasone / salmeterol:

56 major drug interactions (149 brand and generic names)
397 moderate drug interactions (1563 brand and generic names)
18 minor drug interactions (186 brand and generic names)

A total of 111 drugs are known to interact with Tiotropium:

109 moderate drug interactions (611 brand and generic names)
2 minor drug interactions (8 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

August 24, 2000

N/A

WADA Class View classifications

N/A

More Information

Patient Resources

Fluticasone / salmeterol uses

Professional Resources

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Fluticasone / Salmeterol vs Tiotropium

See also:

Breztri Aerosphere

Xolair

Dupixent

Symbicort

Ventolin

Ventolin HFA

Zithromax

Advair Diskus

ProAir HFA

Breo Ellipta

Further information

Comparing Fluticasone / Salmeterol vs Tiotropium

See also:

Further information

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