Fetzima Alternatives Compared
| Fetzima (levomilnacipran) | Rexulti (brexpiprazole) | Auvelity (bupropion / dextromethorphan) |
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| Fetzima (levomilnacipran) | Rexulti (brexpiprazole) | Auvelity (bupropion / dextromethorphan) |
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Prescription only
Prescribed for Major Depressive Disorder, Depression. Fetzima may also be used for purposes not listed in this medication guide. |
Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression, or used to relieve agitation associated with dementia in Alzheimer's disease. Most people... View more |
Prescription only
Auvelity is an oral combination antidepressant tablet containing bupropion and dextromethorphan that has a novel way of working to treat adults with severe depression. Research has shown it is... View more |
Related suggestions Major Depressive Disorder
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| More about Fetzima (levomilnacipran) | More about Rexulti (brexpiprazole) | More about Auvelity (bupropion / dextromethorphan) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Fetzima has an average rating of 5.1 out of 10 from a total of 199 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 44% reported a negative effect. |
Rexulti has an average rating of 6.6 out of 10 from a total of 499 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 25% reported a negative effect. |
Auvelity has an average rating of 8.5 out of 10 from a total of 146 ratings on Drugs.com. 78% of reviewers reported a positive effect, while 6% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Fetzima side effects |
View all Rexulti side effects |
View all Auvelity side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Fetzima prices |
View all Rexulti prices |
View all Auvelity prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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12 hours |
91 hours |
30 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 374 drugs are known to interact with Fetzima:
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A total of 601 drugs are known to interact with Rexulti:
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A total of 698 drugs are known to interact with Auvelity:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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July 25, 2013 |
July 10, 2015 |
August 18, 2022 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.