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Crestor Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Crestor Atorvastatin Simvastatin
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Crestor (rosuvastatin) Atorvastatin Simvastatin
Prescription only

Crestor appears as effective as atorvastatin at lowering cholesterol; however, grapefruit products do not affect Crestor to the same extent as atorvastatin. People of Asian descent may be more... View more

Prescription only

Atorvastatin is effective at lowering cholesterol; however, its use may be limited by side effects such as muscle pain. Prescribed for High Cholesterol, High Cholesterol - Familial Heterozygous... View more

Prescription only

Simvastatin is effective at lowering cholesterol; however, it may cause muscle pain particularly at higher dosages. Prescribed for Cardiovascular Risk Reduction, High Cholesterol, High Cholesterol -... View more

More about Crestor (rosuvastatin) More about Atorvastatin More about Simvastatin
Generic Status

Lower-cost generic is available

Lower-cost generic is available

Lower-cost generic is available
Ratings & Reviews

Crestor has an average rating of 5.9 out of 10 from a total of 132 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 34% reported a negative effect.

Atorvastatin has an average rating of 4.2 out of 10 from a total of 281 ratings on Drugs.com. 28% of reviewers reported a positive effect, while 57% reported a negative effect.

Simvastatin has an average rating of 4.8 out of 10 from a total of 127 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 49% reported a negative effect.

View all 132 reviews

View all 281 reviews

View all 127 reviews

Drug Class
Side Effects

Common side effects include:

  • myalgia

See also: Crestor side effects in more detail.

Commonly reported side effects include:

  • hemorrhagic stroke
  • arthralgia
  • diarrhea
  • nasopharyngitis

See also: atorvastatin side effects in more detail.

See also: simvastatin side effects in more detail.
Pricing and Coupons * Prices are without insurance
Quantity 90 tablet
Dosage 10 mg
Per Unit* $9.81
Cost* $883.11

View all Crestor prices and generic prices

Quantity 50 each
Dosage 20 mg
Per Unit* $0.43 - $0.63
Cost* $21.53 - $31.70

View all atorvastatin prices

Quantity 100 each
Dosage 40 mg
Per Unit* $0.27 - $0.95
Cost* $27.19 - $95.00

View all simvastatin prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Dosage Form(s) Available
  • Oral tablet
  • Oral tablet
  • Oral tablet
Brand Names
Other rosuvastatin brands include: Ezallor Lipitor FloLipid, Zocor
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

19 hours

14 hours

N/A
CSA Schedule ** View glossary of terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
X
Category X Not for use in pregnancy

See the full pregnancy warnings document.
X
Category X Not for use in pregnancy

See the full pregnancy warnings document.
X
Category X Not for use in pregnancy

See the full pregnancy warnings document.
Drug Interactions

A total of 204 drugs are known to interact with Crestor:

  • 25 major drug interactions (80 brand and generic names)
  • 168 moderate drug interactions (505 brand and generic names)
  • 11 minor drug interactions (89 brand and generic names)

A total of 345 drugs are known to interact with atorvastatin:

  • 43 major drug interactions (140 brand and generic names)
  • 268 moderate drug interactions (763 brand and generic names)
  • 34 minor drug interactions (246 brand and generic names)

A total of 288 drugs are known to interact with simvastatin:

  • 56 major drug interactions (225 brand and generic names)
  • 222 moderate drug interactions (579 brand and generic names)
  • 10 minor drug interactions (51 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Rosuvastatin may cause liver problems and using it with substantial quantities of alcohol may... View more
  • Grapefruit juice can increase the blood levels of atorvastatin. This can increase the risk of side... View more
  • Atorvastatin may cause liver problems and using it with substantial quantities of alcohol may... View more
  • Grapefruit juice can significantly increase the blood levels of simvastatin. This can increase the... View more
  • Simvastatin may cause liver problems and using it with substantial quantities of alcohol may... View more
Disease Interactions
First Approval Date

August 12, 2003

December 17, 1996

December 23, 1991
WADA Class View World Anti-Doping Agency classifications.

N/A

N/A

N/A
More Information
Patient resources
Professional Resources
Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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