Crestor Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Crestor (rosuvastatin)	Atorvastatin	Simvastatin	Enter another drug to compare

Crestor (rosuvastatin)

Atorvastatin

Simvastatin

Prescription only

Crestor is used to reduce the risk of major cardiovascular (CV) events or to lower high cholesterol as an adjunct to diet or other lipid-lowering treatments. It appears as effective as atorvastatin... View more

Prescription only

Atorvastatin is effective at lowering cholesterol; however, its use may be limited by side effects such as muscle pain. Prescribed for High Cholesterol, High Cholesterol - Familial Homozygous, High... View more

Prescription only

Simvastatin is effective at lowering cholesterol; however, it may cause muscle pain, particularly at higher dosages. Should not be used by people with active liver disease or in women planning a... View more

More about Crestor (rosuvastatin)

More about Atorvastatin

More about Simvastatin

Ratings & Reviews

Crestor has an average rating of 5.6 out of 10 from a total of 139 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 36% reported a negative effect.

Atorvastatin has an average rating of 4.3 out of 10 from a total of 302 ratings on Drugs.com. 28% of reviewers reported a positive effect, while 54% reported a negative effect.

Simvastatin has an average rating of 4.8 out of 10 from a total of 131 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 48% reported a negative effect.

View all 139 reviews

View all 302 reviews

View all 131 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Pain (20.1%)
Muscle pain (19.4%)
Joint pain (15.1%)
Weakness (11.5%)
Cramps (10.8%)
Dizziness (6.5%)
Insomnia (6.5%)

View all Crestor side effects

Muscle pain (19.2%)
Pain (18.5%)
Weakness (10.9%)
Dizziness (10.3%)
Cramps (8.6%)
Headaches (8.6%)
Memory loss (7.3%)

View all Atorvastatin side effects

Insomnia (11.5%)
Pain (11.5%)
Weakness (9.2%)
Cramps (8.4%)
Muscle pain (8.4%)
Tiredness (7.6%)
Headaches (6.9%)

View all Simvastatin side effects

Drug Class

Statins

Statins

Statins

Generic Availability

Lower cost generic approved

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	90 tablet
Strength	10 mg
Per unit^*	$9.95
Cost^*	$895.66

View all Crestor prices

Quantity	50 each
Strength	20 mg
Per unit^*	$0.40 - $0.57
Cost^*	$19.91 - $28.28

View all Atorvastatin prices

Quantity	100 each
Strength	40 mg
Per unit^*	$0.25 - $1.53
Cost^*	$24.57 - $152.61

View all Simvastatin prices

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Dosage Forms

Oral tablet

Oral tablet

Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

19 hours

14 hours

N/A

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category X Not for use in pregnancy

See the full pregnancy warnings document.

Category X Not for use in pregnancy

See the full pregnancy warnings document.

Category X Not for use in pregnancy

See the full pregnancy warnings document.

Drug Interactions

A total of 248 drugs are known to interact with Crestor:

38 major drug interactions (108 brand and generic names)
199 moderate drug interactions (582 brand and generic names)
11 minor drug interactions (96 brand and generic names)

A total of 406 drugs are known to interact with Atorvastatin:

47 major drug interactions (149 brand and generic names)
324 moderate drug interactions (898 brand and generic names)
35 minor drug interactions (255 brand and generic names)

A total of 337 drugs are known to interact with Simvastatin:

60 major drug interactions (234 brand and generic names)
265 moderate drug interactions (689 brand and generic names)
12 minor drug interactions (59 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Rosuvastatin may cause liver problems and using it with substantial quantities of alcohol may... View more

Grapefruit juice can increase the blood levels of atorvastatin. This can increase the risk of side... View more
Atorvastatin may cause liver problems and using it with substantial quantities of alcohol may... View more

Grapefruit juice can significantly increase the blood levels of simvastatin. This can increase the... View more
Simvastatin may cause liver problems and using it with substantial quantities of alcohol may... View more

Disease Interactions

First Approval Date

August 12, 2003

December 17, 1996

December 23, 1991

WADA Class View classifications

N/A

More Information

Patient Resources

Crestor uses

Atorvastatin uses

Simvastatin uses

Professional Resources

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Crestor Alternatives Compared

See also:

Ezallor

Altoprev

Dupixent

Atorvaliq

FloLipid

Lescol XL

Lipitor

Livalo

Zocor

Zypitamag

Further information

Crestor Alternatives Compared

See also:

Further information

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