Comparing Alprazolam vs Sertraline
| Alprazolam | Sertraline |
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| Alprazolam | Sertraline |
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Prescription only
Alprazolam is used for the acute treatment of generalized anxiety disorder (GAD) and panic disorder (PD) in adults. It is addictive, and withdrawal symptoms can be severe. Other common side effects... View more |
Prescription only
Sertraline is used to treat mood disorders such as depression, anxiety, OCD, PTSD, panic disorder, and premenstrual dysphoric disorder (PMDD). Headaches, nausea, diarrhea, weight loss, insomnia... View more |
Related suggestions Depression
Borderline Personality Disorder
Dysautonomia
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| More about Alprazolam | More about Sertraline | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Alprazolam has an average rating of 8.6 out of 10 from a total of 1500 ratings on Drugs.com. 83% of reviewers reported a positive effect, while 8% reported a negative effect. |
Sertraline has an average rating of 7.3 out of 10 from a total of 4600 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Alprazolam side effects |
View all Sertraline side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Alprazolam prices |
View all Sertraline prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Alprazolam Intensol, Xanax, Xanax XR | Zoloft | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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20 hours |
66 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 565 drugs are known to interact with Alprazolam:
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A total of 675 drugs are known to interact with Sertraline:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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October 16, 1981 |
December 30, 1991 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.