Alka-Seltzer Plus Cold and Sinus Alternatives Compared
| Alka-Seltzer Plus Cold and Sinus (acetaminophen / phenylephrine) | Pseudoephedrine | Phenylephrine |
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| Alka-Seltzer Plus Cold and Sinus (acetaminophen / phenylephrine) | Pseudoephedrine | Phenylephrine |
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Over-the-counter
Prescribed for Sinus Symptoms, Nasal Congestion. Alka-Seltzer Plus Cold and Sinus may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Pseudoephedrine is used for self-medication for the temporary relief of nasal congestion associated with upper respiratory allergy (such as hay fever), sinusitis, or the common cold. It is effective... View more |
Prescription and OTC
Phenylephrine is used to temporarily unblock a nose or relieve sinus pressure in people with nasal and sinus congestion caused by colds, allergies, or hay fever. Injectable phenylephrine may be used... View more |
Related suggestions Nasal Congestion
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| More about Alka-Seltzer Plus Cold and Sinus (acetaminophen / phenylephrine) | More about Pseudoephedrine | More about Phenylephrine | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Be the first to share your experience with this drug. |
Pseudoephedrine has an average rating of 6.5 out of 10 from a total of 95 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 29% reported a negative effect. |
Phenylephrine has an average rating of 6.4 out of 10 from a total of 24 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 38% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
View all Pseudoephedrine side effects |
View all Phenylephrine side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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N/A |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Pseudoephedrine prices |
View all Phenylephrine prices |
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| Dosage Forms | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
| Other acetaminophen / phenylephrine brands include: Congespirin Aspirin Free, Contac Cold + Flu (Day Formula), D-Time Sinus, Day Relief Sinus PE, Dilotab II, Excedrin Sinus Headache, Mapap Sinus Congestion and Pain, Panadol Cold + Flu Non-Drowsy, Robitussin Peak Cold Nasal Relief, Sinus Congestion and Pain Daytime Cool Ice, Sinutab Sinus Maximum Strength, Sudafed PE Sinus Pressure + Pain, Suphedrine PE Sinus Headache, Tylenol Plus Children's Cold & Stuffy Nose, Tylenol Sinus + Headache Day, Vicks QlearQuil Daytime Sinus & Congestion, Vicks Sinex Daytime View more | 12 Hour Decongestant, 12 Hour Nasal Decongestant, Afrinol, Allermed, Cenafed, Children's Dimetapp Decongestant Infant, Chlor-Trimeton Nasal Decongestant, Contac Cold, Decofed, Decofed Liquid, Drixoral Decongestant Non-Drowsy, Efidac, Elixsure Decongestant, Entex, Genaphed, nasofed, Nexafed Nasal Decongestant, Novafed, Silfedrine, Sudafed 12-Hour, Sudafed 24-Hour, Sudafed Congestion, SudoGest, SudoGest 12 Hour, Suphedrin, Suphedrine, Zephrex-D View more | AH-Chew D, Biorphen, Congest Aid II, Contac-D, Despec-SF, Dimetapp Toddler's Drops Decongestant, Gilchew IR, Little Colds Decongestant, Nasal Decongestant PE, Nasop, Nasop12, Neo-Synephrine, Ricobid-D, Sudafed PE Children's Nasal Decongestant, Sudafed PE Congestion, Sudogest PE, Suphedrine PE, Vazculep View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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8 hours |
16 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 340 drugs are known to interact with Alka-Seltzer Plus Cold and Sinus:
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A total of 220 drugs are known to interact with Pseudoephedrine:
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A total of 201 drugs are known to interact with Phenylephrine:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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N/A |
N/A |
December 20, 2012 |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
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| More Information | ||||||||||||||||||
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N/A |
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| Related Treatment Guide | ||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.