Phenylephrine Drug Interactions
A total of 320 drugs (1377 brand and generic names) are known to interact with phenylephrine.
- 54 major drug interactions (293 brand and generic names)
- 263 moderate drug interactions (1071 brand and generic names)
- 3 minor drug interactions (13 brand and generic names)
Check for interactions with phenylephrine
Common medications checked in combination with phenylephrine
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- Cymbalta (duloxetine)
- Dextromethorphan HBr Adult Formula (dextromethorphan)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Lyrica (pregabalin)
- Mucinex (guaifenesin)
- Nexium (esomeprazole)
- Paracetamol (acetaminophen)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
phenylephrine disease Interactions
There are 4 disease interactions with phenylephrine which include:
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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