Skip to Content

Acetaminophen / Phenylephrine Dosage

Medically reviewed by Drugs.com. Last updated on Jun 6, 2019.

Applies to the following strengths: 325 mg-5 mg; 650 mg-10 mg; 500 mg-15 mg; 250 mg-5 mg; 80 mg-1.25 mg; 500 mg-5 mg

Usual Adult Dose for Nasal Congestion

325 mg acetaminophen / 5 mg phenylephrine tablets/gelcaps: 2 orally every 4 hours
Maximum dose: 5 doses per day

500 mg acetaminophen / 5 mg phenylephrine tablets: 2 orally every 6 hours
Maximum dose: 4 doses per day

Usual Adult Dose for Sinus Symptoms

325 mg acetaminophen / 5 mg phenylephrine tablets/gelcaps: 2 orally every 4 hours
Maximum dose: 5 doses per day

500 mg acetaminophen / 5 mg phenylephrine tablets: 2 orally every 6 hours
Maximum dose: 4 doses per day

Usual Adult Dose for Headache

325 mg acetaminophen / 5 mg phenylephrine tablets/gelcaps: 2 orally every 4 hours
Maximum dose: 5 doses per day

500 mg acetaminophen / 5 mg phenylephrine tablets: 2 orally every 6 hours
Maximum dose: 4 doses per day

Usual Pediatric Dose for Nasal Congestion

325 mg acetaminophen / 5 mg phenylephrine tablets/gelcaps:
12 years and older: 2 orally every 4 hours
Maximum dose: 5 doses per day

500 mg acetaminophen / 5 mg phenylephrine tablets:
12 years and older: 2 orally every 6 hours
Maximum dose: 4 doses per day

Usual Pediatric Dose for Sinus Symptoms

325 mg acetaminophen / 5 mg phenylephrine tablets/gelcaps:
12 years and older: 2 orally every 4 hours
Maximum dose: 5 doses per day

500 mg acetaminophen / 5 mg phenylephrine tablets:
12 years and older: 2 orally every 6 hours
Maximum dose: 4 doses per day

Usual Pediatric Dose for Headache

325 mg acetaminophen / 5 mg phenylephrine tablets/gelcaps:
12 years and older: 2 orally every 4 hours
Maximum dose: 5 doses per day

500 mg acetaminophen / 5 mg phenylephrine tablets:
12 years and older: 2 orally every 6 hours
Maximum dose: 4 doses per day

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Use with caution in liver disease.

Precautions

CONTRAINDICATIONS:
-Hypersensitivity to any of the ingredients
-Current use of any other drug containing acetaminophen.
-Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI.

Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide