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Acetaminophen / Phenylephrine Dosage

Medically reviewed by Drugs.com. Last updated on Jul 31, 2023.

Applies to the following strengths: 325 mg-5 mg; 650 mg-10 mg; 500 mg-15 mg; 250 mg-5 mg; 80 mg-1.25 mg; 500 mg-5 mg

Usual Adult Dose for Nasal Congestion

325 mg acetaminophen / 5 mg phenylephrine tablets/gelcaps: 2 orally every 4 hours
Maximum dose: 5 doses per day

500 mg acetaminophen / 5 mg phenylephrine tablets: 2 orally every 6 hours
Maximum dose: 4 doses per day

Usual Adult Dose for Sinus Symptoms

325 mg acetaminophen / 5 mg phenylephrine tablets/gelcaps: 2 orally every 4 hours
Maximum dose: 5 doses per day

500 mg acetaminophen / 5 mg phenylephrine tablets: 2 orally every 6 hours
Maximum dose: 4 doses per day

Usual Adult Dose for Headache

325 mg acetaminophen / 5 mg phenylephrine tablets/gelcaps: 2 orally every 4 hours
Maximum dose: 5 doses per day

500 mg acetaminophen / 5 mg phenylephrine tablets: 2 orally every 6 hours
Maximum dose: 4 doses per day

Usual Pediatric Dose for Nasal Congestion

325 mg acetaminophen / 5 mg phenylephrine tablets/gelcaps:
12 years and older: 2 orally every 4 hours
Maximum dose: 5 doses per day

500 mg acetaminophen / 5 mg phenylephrine tablets:
12 years and older: 2 orally every 6 hours
Maximum dose: 4 doses per day

Usual Pediatric Dose for Sinus Symptoms

325 mg acetaminophen / 5 mg phenylephrine tablets/gelcaps:
12 years and older: 2 orally every 4 hours
Maximum dose: 5 doses per day

500 mg acetaminophen / 5 mg phenylephrine tablets:
12 years and older: 2 orally every 6 hours
Maximum dose: 4 doses per day

Usual Pediatric Dose for Headache

325 mg acetaminophen / 5 mg phenylephrine tablets/gelcaps:
12 years and older: 2 orally every 4 hours
Maximum dose: 5 doses per day

500 mg acetaminophen / 5 mg phenylephrine tablets:
12 years and older: 2 orally every 6 hours
Maximum dose: 4 doses per day

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Use with caution in liver disease.

Precautions

CONTRAINDICATIONS:


Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.