Comparing Afrin vs Flonase
| Afrin | Flonase |
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| Afrin (oxymetazoline) | Flonase (fluticasone) |
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Over-the-counter
Prescribed for Nasal Congestion. Afrin may also be used for purposes not listed in this medication guide. |
Over-the-counter
Flonase reduces inflammation and nasal symptoms associated with rhinitis; however, Flonase may cause nose bleeds and it takes about three days for the full effects to be seen. Prescribed for... View more |
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| More about Afrin (oxymetazoline) | More about Flonase (fluticasone) | ||||||||
| Ratings & Reviews | |||||||||
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Afrin has an average rating of 3.4 out of 10 from a total of 133 ratings on Drugs.com. 21% of reviewers reported a positive effect, while 68% reported a negative effect. |
Flonase has an average rating of 4.9 out of 10 from a total of 183 ratings on Drugs.com. 38% of reviewers reported a positive effect, while 51% reported a negative effect. |
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| Drug Class | |||||||||
| Side Effects | |||||||||
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See also: Afrin side effects in more detail. |
See also: Flonase side effects in more detail. |
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| Generic Availability | |||||||||
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N/A |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Afrin prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms Available | |||||||||
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| Brand Names | |||||||||
| Other oxymetazoline brands include: 12 Hour Nasal, 12 Hour Nasal Decongestant Spray, Afrin Allergy Sinus Nasal Spray, Afrin NoDrip Allergy Sinus, Afrin NoDrip Extra Moisturizing, Afrin NoDrip Original, Afrin NoDrip Severe Congestion, Afrin NoDrip Sinus, Afrin Original, Afrin Severe Congestion, Afrin Sinus, Allerest 12 Hour Nasal Spray, CVS Health Sinus Relief, Dristan 12 Hour Nasal Spray, Duramist Plus, Duration, Four-Way Nasal Spray, Genasal, Giltuss Severe Sinus, Mucinex Sinus-Max Clear & Cool, Mucinex Sinus-Max Full Force, Mucinex Sinus-Max Moisture Smart, Nostrilla, Nostrilla 12 Hour, Rhinase D Moisturizing Nasal Decongestant, Todays Health Nasal Relief Extra Moisturizing, Vicks QlearQuil 12 Hour Nasal Decongestant Moisturizing Spray, Vicks Sinex 12-Hour Decongestant Nasal Spray, Vicks Sinex 12-Hour Decongestant UltraFine Mist, Vicks Sinex Moisturizing 12-Hour Decongestant UltraFine Mist, Vicks Sinex Severe Nasal Spray, Zicam Extreme Congestion Relief, Zicam Sinus Relief View more | Other fluticasone brands include: Flonase Allergy Relief, Flonase Sensimist, Ticanase, Xhance | ||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||
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N/A |
8 hours |
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| CSA Schedule ** View glossary of terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 51 drugs are known to interact with Afrin:
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A total of 50 drugs are known to interact with Flonase:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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N/A |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||
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N/A |
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| More Information | |||||||||
| Patient resources | |||||||||
| Professional Resources | |||||||||
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N/A |
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| Related Treatment Guide | |||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.