Afrin Interactions
There are 51 drugs known to interact with Afrin (oxymetazoline nasal), along with 3 disease interactions. Of the total drug interactions, 6 are major, and 45 are moderate.
- View all 51 medications that may interact with Afrin
- View Afrin disease interactions (3)
Most frequently checked interactions
View interaction reports for Afrin (oxymetazoline nasal) and the medicines listed below.
- acetaminophen
- albuterol
- Allegra (fexofenadine)
- amlodipine
- aspirin
- atorvastatin
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- doxycycline
- famotidine
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- fluticasone nasal
- gabapentin
- ibuprofen
- levothyroxine
- lisinopril
- losartan
- melatonin
- metformin
- Mucinex (guaifenesin)
- omeprazole
- prednisone
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
Afrin disease interactions
There are 3 disease interactions with Afrin (oxymetazoline nasal) which include:
Report options
More about Afrin (oxymetazoline nasal)
- Afrin consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (134)
- Side effects
- Dosage information
- During pregnancy
- Support group
- Drug class: nasal antihistamines and decongestants
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.