Trintellix User Reviews & Ratings (Page 5)

• Hopeful
• Taken for less than 1 month
• September 1, 2020

For Depression "I went into a mild depression but major anxiety situation. I started Trintellix 6 days ago. Today I feel the best. I found myself happy and chatting with everyone I saw. I had slight nausea the first 4 days. I took it in the morning with a banana and it was fine. Kept a little something in my stomach the first 3 days. I did have trouble sleeping but took half a Benadryl and it helped. I’m feeling good today. I’m hopeful it will work for me. My doctor said I can come off of it in 90 days. It’s just to build up my seratonin levels. He only suggested 5mg. Try to stay with it if you have no major side effects"

• Moody...
• Taken for less than 1 month
• February 20, 2014

For Depression "I have been on Brintellix 10 mg and increased to 20 mg on 02/19/2014. I have experienced dry mouth, dizziness, forgetfulness, no desire to eat, weight loss of 11 lbs in 10 days, which is good considering I'm overweight, this can't be a bad thing, and wake up often, however, I am in a happier mood and not so stressed out. I have been on Brintellix for a total of 11 days. Hope the yucky side effects go away soon. I have tried almost everything else and nothing has worked mood wise for me as good as this is."

• MP2014
• April 3, 2014

For Depression "I've tried so many antidepressants but this one has been the best. I was on 10mg for a month and just had my dosage increased to 20 mg, two days ago. I do feel sick; nausea and a little disoriented but those are bearable side effects to me. I have had energy, better concentration but the biggest thing I love about this antidepressant is that I have my sex drive back. My libido wasn't affected like it has been in the past with other meds; I've actually had increased sex drive. So far I feel "okay" but hopefully since 20mg is the therapeutic dose, that I feel more "content" or "happy" with my life soon. "

• Aunti...
• May 15, 2015

For Depression "I was on Lexapro for about 2 years until itstopped working. Prior to that,over the last 25 years was always on an antidepressant. You name it, I've tried it. What the antidepressants did for me was just take away the severe irritability that I had, I was really at a low point when my doctor asked me to try Brintellix. I had no desire to do anything. I felt no joy. I had been taking 40 mg.of Lexapro a day. Doc said I didn't have to wean off it. He said I could just switch, starting the next day and I did. I Started on 5mg for the first 2 wks then increased to 10mg it's only been 4wks that I have been on it and my nausea has got better, I have a clarity in thinking that I didn't have before. I feel joy now. I am staying on it. Also, no sexual problems on it. Got Hope!"

• FigsM...
• Taken for 1 to 6 months
• March 1, 2019

For Depression "Updating my review as I have now been taking Trintellix 10mg for 5 weeks. Feeling great, no nausea unless I drink a glass of wine. I was taking in the morning but it was making me very sleepy early in the evenings. Now I take at about 2:30 pm and that is working great for me. It has regulated my sleep so that in itself has changed my life! It has really helped me with my severe social anxiety and my low feeling is beginning to lift. I have no feeling of being medicated at all. My insurance is covering it thanks to my Dr. and his prior approval letter showing other meds did not work for me. My copay is $60 and there is a savings card with Trintellix on their website that brought my cost down to $10."

• Londo...
• December 4, 2015

For Depression "Am 61 male. Tried all SSRI's and MAOI's for persistent depression over 9 years. Most recent was Prozac. None of these worked beyond moderate improvement. Depression and anxiety attended me constantly. I used Lorazepam to sleep effectively. I went on Brintellix 10 mg and within 2 weeks felt stable and able to deal with challenging personal setbacks with clarity and resolve. I think that 4 months into it I have found a drug that truly works."

• Works...
• Taken for less than 1 month
• March 12, 2024

For Major Depressive Disorder "I have been on 5 mg Trintellix for 1 month. The only side effects I've had are somewhat dry mouth sometimes, and not being able to sleep as well as I used to. Other than those 2 things, it has worked great for me! For the first 1-2 weeks, I did continue to have some bad days, but starting about week 3, the bad times became less extreme and have continued to do so. My insurance wouldn't pay for it, so I applied for assistance on the manufacturer's website, and received it for free."

• Senne...
• Taken for less than 1 month
• February 28, 2014

For Depression "I have been taken 10 mg for 3 weeks. I have taken other anti depressants before with very little to no help. With this one I feel a lot better, I have more energy, I can focus and concentrate better. My mind is clearer than it has been for a long time and I am happier. So far I have no side effects besides I am a little constipated."

• Trint...
• Taken for 1 to 2 years
• June 5, 2020

For Major Depressive Disorder "Definitely mixed feelings about Trintellix after being on this medication for a year. Prior to this I took Paxil and abandoned that horror due to reduced emotions and feelings for anything or anyone. Began Trintellix and you'd swear I was bipolar (which I'm not). I wake up some mornings, take a 20 mg. tablet and feel happy, but severely anxious. Throughout the day the anxiety builds up until the evening. The evening sucks. The anxiety slowly builds into depression, wake up the next day and it happens all over again like groundhog day."

• mlovesd
• January 6, 2021

For Major Depressive Disorder "I was on every drug in the book for depression, Prozac, Wellburtin, Pristiq, Cipralex, nothing took the edge off at all. Lost my mother to depression in July of 2019. Nothing could be worse. Was not on anything but Prozac at the time, and I wasn't doing well. Addicted to benzos, I was struggling. Doctor placed me on Trintellix, 10mg. Was kind enough to give me samples until I got coverage. Had a bit of a setback and fell into a depression six months later. Was boosted to 20mg and now I am doing fantastic. Depressive episodes do come back for a few days at a time but they are easier to handle if you get back in routine and force yourself. I think this is a great drug, I lost all hope in antidepressants previously."

• jewel...
• April 8, 2014

For Major Depressive Disorder "Great experience so far. Month three, ramping up to 20 mg a day. Constipation side effect eliminated by 2 fiber capsules a day. No sexual side effects and feeling much more like myself! No weight gain! "

• David...
• March 15, 2015

For Depression "I have been using this medication for over a month. I find the side effect of nausea to be very minimal and was gone it about 10 days. My mood is positive and stable. However, I find my focus and concentration to be markedly improved. This medication does what it claims to do. Much better than the others and lower side effects."

• Bella
• May 11, 2019

For Major Depressive Disorder "Prescribed 10 mg a day of Trintellix for depression and the first 10 days I was sick to my stomach and itching, so I take an antihistamine at the same time at bedtime. Day 11 started feeling markedly better, nausea was gone, still itching, but less. Day 14 my overall feeling was 50 percent better than when I started the drug. Today, day 16 saw my doctor again. I had lost weight, my overall anxiety is much better, the depression 70 percent better. All my aches and pains have disappeared. The doctor gave me 2 months of samples and told me to come back in a month if I thought I needed to, otherwise continue as directed. I've been on multiple anti depressants over the years, none worked even half as well as the Trintellix"

• pretty...
• Taken for 6 months to 1 year
• October 26, 2014

For Depression "I love Brilltenex. I've been on it for a year. Unfortunately I take 20 mg. I feel a whole lot better. So much better than Prozac. Only down fall is that my headaches are back. Might lower back to 10mg. Wish it wasn't so expensive."

• cyphe...
• Taken for 6 months to 1 year
• March 6, 2019

For Depression "I have been on effexor and just about everything else (hated getting off effexor - they don't warn you about the addiction before hand), but for the first time ever I can say I am back to a solid, stable 'normal'. Haven't been this happy and upbeat in well over a decade. All the others seemed to help, but I always had small dips and still struggle a lot with fatigue. I took about 2 months for total affect to be realized, but I am very happy. As always - your mileage may very."

• Reborn...
• Taken for 6 months to 1 year
• November 29, 2018

For Major Depressive Disorder "I used to be on generic escitalopram for 6-7 years. It worked really well at the time, but as I was now becoming an adult (21 now), my major depressive episodes were happening more frequently. I had more adult stress; full-time student, part-time worker, full-time bills. It was becoming too much. I switched psychiatrist and psychologist due to personal reasons and insurance. My new psychiatrist gave me free samples of Trintellix to try for a month. She said it's newer than escitalopram, it's usually faster and has more SSRI's. After 6 days, I began to feel really great. I was able to pay attention in lectures again, I felt so energetic that I started going back to the gym, and I just felt more like myself again. Like a 2.0. It could've been a placebo effect, but after taking it for almost a year now, I can tell you I feel incredible :)"

• 29ano
• Taken for 1 to 6 months
• October 8, 2019

For Depression "Tried Zoloft, Wellbutrin and lexapro. Trintellix has been GREAT for me. First six weeks on 10 were “ehh”, like not a big difference, but when I increased to 20mg, it was night and day. I’m happy when I am wake. I have energy. Absolutely amazing results. The nausea is HORRIBLE, but if you can get through it, the results are worth. I took zofran for the nausea, and it worked. It’s only been 3 weeks since my increase, but it’s been great! Good luck and keep trying!"

• Was...
• Taken for 1 to 6 months
• September 24, 2014

For Major Depressive Disorder "I had been diagnosed with Major Depressive Disorder and have been treated with medicines that at that time were the best. Venlafaxine being the latest. However the effects were decreasing over time. 12 years and has so many side effects. Now I am on Brintellix 20mg daily...wow there is life. My mood is elevated, my outlook and self esteem and confidence has returned to normal. My energy level has skyrocketed. My sleep is more restful. Negative thoughts are diminished. Day to day living is now controllable. Clear thought process not drugged feeling. A very content person. Focus on the enabling versus the negativity. Started on 10mg daily increased to 20mg after 3 weeks and a slow reduction in my venlafaxine. One side effect is nausea I noted but a dry snack helps"

• JCano
• August 23, 2019

For Depression "I have been on Trintellix 10 mgs for a week. I noticed something after an hr. My mouth got a strange taste and then vomit. I felt awful after that so I laid down for a few hours. That night I felt different. My mind was clear and I was in a mood to where I felt like speaking to other people. (A rare occasion.) After that I took it on a empty stomach. Still had the strange taste but no vomit. I have been more upbeat and haven't really wanted to take my adderall. I also have noticed that I'm not eating as much. I still get hungry but just eat a lot less. We shall see!!:)"

• Insom...
• Taken for 1 to 6 months
• November 17, 2019

For Depression "I have bipolar disorder and I started having suicidal/homicidal thoughts and urges. When I noticed they weren't going away, I decided to tell my doctor. She started me out on 5mg Trubtellix a day for one week, then upped it to 10mg. I started having headaches at the 10mg, but I refused to give up. About three weeks later, I really noticed it working and the headaches had gone away. I'm glad I stuck with it! I was a little unsure about the fact that I only needed 10mg of it, but it works. No more "bad thoughts""

• FigsM...
• January 25, 2019

For Depression "I have suffered for about 10 years with depression and anxiety. Never suicidal, but I have just always felt like the world was passing me by. So my Dr prescribed Wellbutrin XL 300 mg about 2 years ago and the first 6 months worked just ok. I think it really disrupted my sleep patterns and stopped working completely on taking the edge off the depressed feeling a few months ago. I gained 30 lbs in one year on Wellbutrin, which made me more depressed. A week ago Dr prescribed Trintellix 10mg. The first day I felt a little nauseous, but it quickly subsided after an hour or so. I didn’t realize what a funk I had been in until the Trintellix. I do not feel medicated at all. The fog is lifting, I feel so clear and normal. From the 2nd day I have felt like I am sleeping like a normal person and am able to get up early and get going with my day, clearly. I am hoping my insurance will cover this, my Dr. has assured me he will get me approved and will keep me in samples until then."

• venom...
• Taken for 1 to 6 months
• January 15, 2020

For Depression "I have update after 13 weeks. So I started Trintellix for MDD/Anxiety/OCD. First 2-3 weeks really fast improvement with my energy and motivation, but after 5 - 6 weeks I had severe headache and cold chills. Took a break for 2-3 days and started again. Motivation again but still "not myself". Couldn't sleep with 10 mg, its really activating, my blood pressure went high, so must cut back to 5 mg, seems its ok, no nausea, less brain fog, better cognition. Keep update next."

• Beans...
• Taken for 1 to 6 months
• June 12, 2023

For Major Depressive Disorder "Trintellix was excellent at reducing my anxiety. At my most anxious of times, it would make me feel like it was just another day. My life is super stressful caring for a dying parent so any relief from feeling constantly anxiety-ridden was so helpful. HOWEVER, the side effects outweigh the benefits. I would often feel nauseated and throw up. I got involuntary muscle spasms that have still not gone away 2 months later. I could still enjoy intercourse, but I was never aroused. It also made me feel like I had an eating disorder. When I was hungry, I was HUNGRY. I would overeat and consume WAY too much - especially sugar. I gained like 15-20 lbs on Trintellix and had to be put on blood pressure medication for the first time in my life. Ultimately, my doctor decided it wasn't in my best interest to continue using it. When I got off of Trintellix, I felt like a cloud have been lifted. I felt happier and could feel emotions again. I've also lost some of the weight I put on from using it."

• jame...
• Taken for less than 1 month
• January 8, 2015

For Depression "I have been on Brintellix for about 3 weeks now. So far I've noticed increased energy, weight loss, nausea, headaches, loss of sleep, nightmares, and some aggression. I have finally found 1 that works and I'm having all these side effects. I started out on the 10mg and still currently taking the 10mg. Maybe I need to be on a lower dose. I also take Ambien 10mg for sleep. "

• Mikey...
• Taken for 6 months to 1 year
• March 31, 2023

For Major Depressive Disorder "Trintellix has been a life saver. It’s extremely powerful and the side effects are low. It works rather quickly compared to other Antidepressants . It’s kind of like Wellbutrin as the mechanism of action is different than most SSRI / SNRI . It has its own unique feeling . Not as bad emotional blunting and horrible sexual side effects like Zoloft or Prozac . It’s very expensive with no generic available but the insurance companies are starting to cover it and there is supposed to be a generic available in 2027 hopefully. I was in a dark place and it pulled me out . Also it’s not extremely addictive like other antidepressants."