Trimethoprim for Urinary Tract Infection User Reviews (Page 3)

• JB6...
• Taken for less than 1 month
• November 25, 2016

"Cleared up the UTI, but 5 weeks after taking the final tablet, I'm still having side effects. First noticed that I had a sore throat and stiff neck after taking tablets for 5 days (was given a seven-day course) but did not make the connection with taking antibiotics. Continued to take medication. I then developed a sensitive scalp, neck pain got worse, and on-and-off headaches plus shoulder and back pain. Felt awful. I was on holiday at the time, and it seemed to ease after about a week. Reported to my GP on returning to the UK. Now, 5 weeks later, on holiday again, neck pain, sore skin, and head pains are all back. Hope this helps others. Not sure if I should seek medical attention or just hope problems go away with time."

• Dav...
• January 1, 2020

"Prescribed trimethoprim for UTI at a walk-in clinic 4 days ago (after nearly 4 hours of sitting there). Not aware of any side effects, and today the agony has ended. So for me, it has worked, for which I am grateful, but certainly not a quick fix. Prescribed 200 mg tablets twice a day for 7 days."

• Hel...
• Taken for less than 1 month
• November 30, 2021

"Got 200 mg to be taken twice daily for a UTI. Night one, I started to vomit and had zero energy with an indescribable migraine, I put it down to the UTI making me poorly. Over the next few days, I started to have my muscles cramp up massively, my arms and legs would not move, and the energy to move them was too much. It also caused unbelievable acid reflux, I could not eat for a week, literally zero appetite. Lost a lot of weight. The last two days, the anxiety, insomnia, and panic attacks set in. This is when I checked on here for reviews and realized I wasn't the only one. It cleared the infection, but boy, what I put down over the week was something else, please find an alternative if you can."

• Dam...
• May 13, 2020

"Was prescribed trimethoprim for a medium-grade UTI that Ural and Hiprex couldn’t quite clear. 1 x 300 mg for 7 days, 1st day I took two tablets. UTI has NOT gone away and seems to be getting worse again. Feeling fatigued and exhausted on this drug too, also off psychologically. This is the 3rd time I’ve taken it, belatedly remember that last time didn’t work too, and I went back to a female doctor who prescribed another round BUT ALSO wrote a penicillin script “in case it still doesn’t clear up,” which all UTI-prone females know does the job. I ended up ditching the trimethoprim and took the penicillin instead, which worked. My opinion as a 37-year-old female: refuse trimethoprim if you’re not allergic to penicillin. It doesn’t seem to be effective in the one 300 mg/day dose against UTIs, and the side effects alone on that amount are crappy. I’d rather a dose of thrush and the UTI efficiently gotten rid of than the side effects of this drug and the damn UTI STILL NOT cleared up."

• Kri...
• Taken for less than 1 month
• March 25, 2023

"Since taking this drug, I've been having the worst anxiety and insomnia in my life. Had to start sleeping pills, that's how bad my insomnia became. Body shakes, numb limbs, panic attacks, and of course, diarrhea. Be careful taking this!"

• Tre...
• Taken for less than 1 month
• February 10, 2023

"Like many others on here, this drug and I don't get on. Two days in - anxiety overload, loss of appetite, feeling of pending doom, and no sleep. Can't really comment on its effectiveness because I couldn't endure it longer than two dosages... Won't be revisiting trimethoprim."

• FRE...
• Taken for less than 1 month
• February 16, 2020

"I was given ALPRIM for a bladder infection. I was told to take it in the evening with food. The first night I nearly went mad, I had nausea, itching, headache, pain in my lower legs and feet. Then on day 2, a severe rash appeared, and my feet both swelled. They were also red raw, I thought I must have had gout. Day 3, I took another tablet, and the rash spread on both legs. The pain was unbearable, moods were hard to live with. I have had infected cellulitis, and that was painful, but nothing like this. So on day 4, the lower legs all blistered, and I was in shocking pain. So that was the end of ALPRIM-never again. It is 3 weeks later, and the legs are slowly coming back to normal, still very red. So please be aware of this medication, and if you notice any changes in yourself, stop it. I will never take it again."

• Chu...
• Taken for less than 1 month
• December 27, 2021

"Prescribed a three-day course (one twice a day) for UTI over the phone. First day gave me a raging headache and dizziness. The second day (Xmas Eve) I felt nauseous all day. Decided to take my second dose with food. An hour later I started vomiting and violently shaking. This lasted a few hours when it seemed to subside (I'm 2 weeks post-COVID, so it's easy to blame COVID for everything, but this felt different). Xmas Day morning, the vomiting returned, along with the violent shaking - no fever. Also, my mind was full of paranoid thoughts. I have never been so scared in my life. Rang 111, the doctor said it was a reaction to the trimethoprim and to stop taking them (I had). Prescribed anti-sickness tablets and advised to call back if symptoms worsened. Thankfully, by Boxing Day I had recovered. I just can't believe these side effects aren't made common knowledge."

• Mol...
• Taken for less than 1 month
• November 10, 2019

"Trimethoprim worked fine 2 months ago but got another UTI and was given 3 days of treatment while waiting for hospital culture to be done. Trimethoprim makes me very, very tired and bad depression and just no appetite. Only one more day to go, so hopefully my appetite will pick up when dose is over."

• Anonymous
• Taken for less than 1 month
• December 24, 2022

"Prescribed a 7-day course of 300 mg twice a day. Felt OK on day 1 and 2, but day 3 was bad. Woke up jittery and shaky, bloated stomach, and no appetite. Took the morning tablet, and two hours later, I was having a panic attack, shaking with chills—nausea and bloating continued, as well as the jittery and shaky feelings. My neck is stiff and uncomfortable also. It's now the evening on day 3, and I'm still shaky and have no appetite. I do take antidepressants and feel this has definitely not helped with my anxiety. I can't take many antibiotics either, as I am sensitive, this is clearly another one to add to the list."

• Mar...
• November 21, 2021

"I start off by telling you shouldn't read reviews. This is my second antibiotic for UTI. I was terrified of taking the two antibiotics as I had suffered panic attacks on day 3 of trimethoprim, no side effects yet, so don't read reviews, everyone is different."

• Jen...
• Taken for less than 1 month
• June 29, 2018

"The urine tract infection is gone after two doses, but at a cost. Feeling nausea, vomiting, itchy rash on ear, slight temperature increase, a terrible headache. I stopped taking it after the second dose by doctor's advice."

• Gre...
• Taken for less than 1 month
• December 8, 2019

"Been on this antibiotic trimethoprim for three days and no side effects. I’m on a longer course of the same drug. I mainly get headaches and nausea from this stuff and a bit of gas too. Been struggling mentally, I’m not sure if that’s related. It’s clearing up the infection well enough though, and having to deal with the pain in the butt of UTI symptoms for the past month, that’s good enough for me. I’m currently on day 3 of a 7-day course."

• Hip...
• Taken for less than 1 month
• September 16, 2020

"I started on a 3-day course of trimethoprim on Monday for a UTI. It gave me severe diarrhea within a day. Never again. I am prone to UTIs. I usually get something else called cephalexin, but not this time, so ending up with severe migraine and diarrhea."

• Anonymous
• April 19, 2017

"I was prescribed Trimethoprim for a urinary tract infection and found that I started spotting and had no clue why this was happening. I felt alarmed and tried to find out the reason, but later after I got the urine test reports, I found that I did not have any infection and was taking this antibiotic for no reason, so I was asked to discontinue the antibiotic. When I stopped the medicine, the spotting stopped. I wanted to share this information as there is no mention of this side effect for this medicine anywhere."

• Boo...
• Taken for 1 to 6 months
• September 22, 2017

"This drug worked very well for me and cleared up my UTI in a matter of 48 hours, although I was on a 7-day course of 2x200 mg daily. Unfortunately, once the tablets finished, the infection returned, so I needed a 2nd course. I'm currently taking a low dose in the evening to keep the infection at bay while the specialists do some tests. I normally get every side effect going and dread taking new medication in any form, especially after a horrific experience with Ciprofloxacin, but the only side effect I experienced with this was itchy ankles and feet on day two, but that didn't last into the third day, so I would class this as a minor side effect and insignificant. Good luck."

• Bus...
• Taken for less than 1 month
• November 24, 2019

"I was prescribed a 3-day course of Alprim, one per night for a urinary tract infection. After taking the first tablet, a red blotchy rash appeared on my lower legs, extremely itchy. The next day, I noticed blisters had appeared in the rash. I also was extremely tired and had a burning feeling in my stomach, but as I only had one tablet to go to finish the course, I continued to take it, as I did not want the urinary tract infection to return. Two days after completing the course, the blistered rash is still with me, although the itching has ceased. The UTI has gone, but I will never take this again as I have really suffered, this must be an allergic reaction."

• Lad...
• Taken for less than 1 month
• May 15, 2022

"Was given a 3-day course of trimethoprim 200 mg twice a day. By day three, although UTI pain had gone, I started to feel so ill. Lethargic, achy, itchy, and nauseous, and by day five, I felt so nauseous I struggled to eat much at all. Now, nearly a month later, I still feel rough, have a very uncomfortable stomach and bowel, and feel constantly nauseous, just generally unwell. I think this antibiotic has played havoc with my system, and it is going to take a while for my body to fully recover. I won’t be having it again, I will ask for something different."

• Mam...
• Taken for less than 1 month
• January 15, 2019

"Taken for a UTI. I started having headaches with them and itching. Then, after a few days, I was covered in a rash, and my face had swollen up. I found it difficult to swallow. I had hives all inside my mouth. I had an allergic reaction to the tablet."

• ste...
• Taken for less than 1 month
• March 26, 2020

"Curses. Back on this absolutely rotten Alprim, but I have no choice. Keflex was OK for the UTI, but it seems the bug likes it and wants to holiday in my bladder. Alprim gives me the worst headache, plus feeling quite sick. Grit the teeth and get on with it. Of course, I will. Waiting now for the result of the urine test to make sure Alprim will work. Sorry for the grizzle. I really have nothing to moan about. Love to all."

• Tan...
• Taken for less than 1 month
• November 13, 2015

"I was prescribed trimethoprim by my GP. I was a little confused as I was 25 weeks pregnant at the time. The drug can still be prescribed, but during testing, it was observed to cause some problems. Needless to say, the drug didn't work. I, as usual, ended up with thrush from the tablets, and when I had a check-up a week later, I still had the infection. The doctor has prescribed Nitrofurantoin. These pose a lesser risk to my baby but are a lower dose. Fingers crossed these will work. I live in the UK."

• Ton...
• Taken for less than 1 month
• September 29, 2024

"Started taking trimethoprim 300 mg for UTI. Two hours after taking it, I felt like I was shaking inside. Went to bed as I thought I’d just sleep it off, slept for a whole hour, then couldn’t sleep for the rest of the night. The insomnia was horrible. Also, woke up with my heart racing. I’m not even going to risk taking a second tablet. Never again for me."

• Kiw...
• Taken for less than 1 month
• July 22, 2021

"I had an uncomplicated UTI and was prescribed a 6-day course of TMP. After the first tablet, I developed intense nausea, chills, and overwhelming fatigue. I have now taken 3 tablets and have not eaten in three days. Even the sight of food makes me sick. I pretty much lay on my electric blanket with alternating chills and sweating. I am terminating usage and will never accept this drug again. I think that it did knock out the UTI."

• Den...
• Taken for 2 to 5 years
• February 15, 2020

"Have been suffering from UTIs continually for 6 years. Going from Keflex to Alprim. The infection always comes back. Had Alprim before, but this time on day 1, huge headache. Day 2, extremely thirsty, have the shakes, trembling hands, and nausea. I really don't want to finish these but will take 3 all up and go back to the doctor."

• Cra...
• Taken for less than 1 month
• August 26, 2016

"I was taking 200 mg over 3 days. On the second day, I got horrendous neck ache, ear ache, and a sore throat. I stopped taking it, but the symptoms carried on. I'm going back to the doctor's today for something else."