Tramadol for Restless Legs Syndrome User Reviews (Page 5)
Brand names: Tramadol Hydrochloride ER, ConZip Qdolo
Tramadol has an average rating of 8.8 out of 10 from a total of 123 reviews for the off-label treatment of Restless Legs Syndrome. 86% of reviewers reported a positive experience, while 7% reported a negative experience.
Reviews for Tramadol
- Ivan
- Taken for 5 to 10 years
- June 2, 2022
"Only medication that has actually helped with RLS. I have tried everything in the book for it with no results. Now one 50 mg tramadol pill at bedtime has controlled this lifetime condition. No side effects."
- glfngrl
- Taken for 2 to 5 years
- December 27, 2022
"I have successfully used Tramadol (50 mg. daily) in conjunction with .75 mg. of Ropinerole for about 5 years. I am 84 y/o and have had RLS most of my life. I had taken Ropinerole for about 18 years. The first 13 years stand alone. At that point, instead of upping the dosage, my GP suggested I add the Tramadol, due to the augmentation issues with Ropinerole. This has been the perfect combo for me. My next step will be to add another 50 mg. of Tramadol if needed, which my doctor agrees with. I have had NO side effects from either drug, and have enjoyed 7-9 hours sleep nightly since 2005!"
Frequently asked questions
- Can you take tramadol with acetaminophen, ibuprofen, or aspirin?
- How much tramadol should I give my dog?
- How long does tramadol withdrawal last?
- Is tramadol stronger than codeine?
- Anonymous
- Taken for 6 months to 1 year
- December 30, 2023
"I have RLS with strong pain and cramps in legs and arms. I take 2 sifrol every evening at 17:30. This suppresses like 80% of the pain. The remaining pain is still uncomfortable in the evening/night. Three years ago, I took tramadol for a blocked neck. To my big surprise, it also suppressed the remaining pain from RLS. Since then, I can spend my evenings again without pain and discomfort, and watch TV in a relaxed way."
- Anonymous
- August 30, 2011
"I used Ultram for 3 years for chronic back pain/sciatica. It's the only medicine that relieved the pain every time. I took 1-3 50mg pills per day and NEVER had to increase dosage. HOWEVER, I started having memory/attention problems, shaking, blurry vision and possible seizures (being evaluated now). I've been off Ultram for nearly a month now and it feels like the veil has been lifted... like my brain's back, clarity. But my original pain feels twice as bad, I have restless legs syndrome and am sleeping MAYBE 4 hours per night. All are symptoms of withdrawal. It worked great for the pain. "
Are you taking this medicine?
- Loren...
- Taken for 2 to 5 years
- January 1, 2017
"Ohhh, don't take Effexor (Venlafaxine) and Tramadol on the same day! My Doc said not to, but Tram helps me sleep deeply so now and then I do. Well, last night, if those odd muscle jerks and repeated shakes/moves weren't minor seizures than I have no other explanation!"
- Karen
- Taken for 1 to 6 months
- September 10, 2023
"Have experienced RLS for approximately the last 10 years. It has severely impacted my ability to fall asleep at night. While taking tramadol prior to recent knee surgery, I noticed the RLS had all but disappeared. I was taking 2 of the small tablets at bedtime, not certain of the dosage (50 mg each?). After surgery, I no longer had access to tramadol, and the RLS immediately reappeared. I average less than 5 hours of sleep a night now and have found no substitute for tramadol to ease the RLS symptoms."
More FAQ
- How long does it take for tramadol to start working?
- How long does tramadol stay in your system?
- Can you take 800mg ibuprofen with 50mg tramadol?
- Which drugs cause opioid-induced constipation?
- Anonymous
- December 30, 2008
"I take it for back and neck pain. As for Restless legs it does nothing to stop my legs playing up. After it has left my system I have back and neck pain again, and can't get out of bed or walk without a walking stick."
- Anonymous
- Taken for less than 1 month
- May 12, 2017
"I take 50 mgs of Tramadol for moderate pain, as needed. I took 1 pill at 1pm, and not felt the need to follow up yet @8:20 pm. I just had a procedure done for a prostate issue I have had for about 12 years. I am 71 years old. This aggravating condition did not quality for a relatively new procedure called the "UroLift System." The discomfort has not improved too much with medications like Finasteride, and Tamsulosin. The profile of my condition called for the Greenlight Laser Therapy."
- Anonymous
- Taken for 1 to 6 months
- August 14, 2021
"I first was prescription for chronic lower back pain but noticed after a week that it stopped my RLS and I slept better. I figured the better sleep helped with my pain too. So it was win win. I took it for a few months. I noticed after the fact I felt mentally better as well. I do have mild-mod depression, anxiety, panic attacks and OCD which were not bothering me while taking it. I took 1 50mg tab a night. Anyway, I was off them for several years. Then my back flare and I started it again. Second time in my life so I was paying extra attention. A few years ago I was dx with FM and CFS/ME on top of everything else along with IBS/SIBO. Tramadol really helps EVERYTHING for me. I take 1 tab daily as needed for pain. I usually feel better body mind and spirit for about 48hr but then I feel my pains and depression again. Learning it can and has been used for many conditions other than just acute and chronic pain. I'm going to keep researching because antidepressants have not work good for me"
- Nora
- Taken for less than 1 month
- July 14, 2023
"I have been taking pramipexole on prescription for some time now. I had to take tramadol to relieve hip pain. I discovered that my RLS disappeared to my delight. I take one 37.5mg tablet with one 500mg paracetamol. No side effects."
- Misty...
- Taken for less than 1 month
- August 15, 2024
"Requip for RLS augments over time and makes symptoms worse (coming on earlier in the day and stronger symptoms) and also causes “poor impulse control.” Botox injections (200 units per calf) worked on the injected area, but I had breakthrough pain elsewhere in my lower legs. I’m now on tramadol, and if this doesn’t work, the only other option is a low-level dose of methadone. I’m grateful to be under the care of a pioneer movement disorder researcher/neurologist in Houston, TX, even though it’s a 4.5 hr drive for appointments. I’m hopeful after reading all the positive comments about tramadol on their RLS."
- FORMER...
- September 30, 2015
"Tramadol works. Period."
- Bill
- Taken for 1 to 6 months
- March 30, 2019
"Took tramadol for my back pain, but worked better for my restless leg syndrome."
- Anonymous
- Taken for 1 to 2 years
- December 12, 2016
"I suffer from RLS symptoms that start in the evening when I get off work. As long as I take the tramadol as soon as I get off work before symptoms begin, it works fantastically."
- TacoB...
- June 5, 2014
"Saved my life! I pretty much went over the deep end from not being able to sleep. Being treated for sleep apnea has helped too."
- MisterM
- October 30, 2008
Ultram (tramadol) "Although this drug is effective for pain, I experienced horrible withdrawals from it. I was awake for over 30 hours."
- Steve...
- April 21, 2017
"I take 100mg every night and it works for me!!"
- Denny
- May 3, 2015
"I have been on Tramadol 50mg for a number of years due to RLS, I take two at night only. It now is a controlled drug, to which only half the amount is prescribed."
- Mac
- July 20, 2008
"My wife said that my jerking legs stopped jerking, now she can sleep better at night, and I feel good too."
- Anonymous
- Taken for less than 1 month
- October 23, 2017
"I took this for pain for frozen shoulder for almost 3 weeks, RLS went away!"
- Anonymous
- September 19, 2011
Ultram ER (tramadol) "Taken for 3 months and restless legs syndrome gone except twice."
- hobby...
- February 27, 2010
"Tramadol is great for getting rid of the pain, which I've had for 20 months with a broken leg. I've stopped taking it now and I can't sleep. Restless body all night."
- SHORT...
- August 27, 2009
Ultram ER (tramadol) "I have found that Ultram ER does not help the Restless Leg Syndrome. "
- Kieron
- July 10, 2010
"I have tried a lot of medication for restless legs syndrome and tramadol is the only thing that gives me relief."
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
Learn more about Restless Legs Syndrome
Care guides
Symptoms and treatments
Medicine.com guides (external)
More about tramadol
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (1,859)
- Drug images
- Latest FDA alerts (4)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
Patient resources
- Tramadol drug information
- Tramadol Extended-Release Capsules and Tablets
- Tramadol Tablets
- Tramadol Suspension
Other brands
Ultram, Ultram ER, ConZip, Qdolo, ... +2 more
Professional resources
- Tramadol Hydrochloride monograph
- Tramadol Capsules (FDA)
- Tramadol ER (FDA)
- Tramadol Oral Solution (FDA)
- Tramadol Tablets (FDA)
Other brands
Ultram, Ultram ER, ConZip, Qdolo
"I started taking tramadol 22 years ago and has been the only thing that works. 75 to 100 mg at 7 pm alleviates the symptoms of RLS and lasts all night. Unfortunately it is almost impossible to get a doctor to prescribe it today."