Tramadol for Restless Legs Syndrome User Reviews (Page 3)

• Mrs...
• December 2, 2016

"I'm writing my experience and reviews to help someone out there who is suffering from RLS. When I was a teenager, I knew something was wrong with my legs because I would get up in the middle of the night and do exercises until the feelings in my legs went away. My legs bothered me until I graduated from high school. When I was diagnosed with Crohn's disease, I was put on a medication called Simzia shots. I took that medicine for about a year and was immediately taken off it because of the side effects. This medicine damaged some of the nerves in my brain. The nerves that were damaged triggered my legs, and my symptoms returned. I suffered for about 3 months until I just couldn't take it anymore. I'm on Tramadol, and it works miracles."

• Shu...
• December 21, 2015

"I've had RLS for more than a decade. It's hereditary. My respected mother also suffered from it. For the last year, it became too intense to sleep. Requip and other drugs for RLS my neurologist gave didn't work on me. My orthopedic gave me tramadol for lower backache. SURPRISE!! My legs stopped jumping that night. Since then, I'm on it. Unfortunately, it doesn't cure it, so I have to take one pill, 50 mg, every night. The doctor said tramadol is habit-forming, so now I'm trying alternative medicine like homeopathy and Ayurveda. Let's see. Meanwhile, thanks to tramadol, that's letting me sleep."

• Jon...
• July 13, 2010

Tramadol "I have horrible Restless Legs Syndrome. Not just in my legs, and not just when I'm trying to sleep; I experience a horrible tension in my limbs all day. Tramadol (Ultram) completely cured it. Also, I experience chronic pain from an old injury, and Ultram is the only non-opiate medication that actually helps my pain."

• Anonymous
• March 23, 2012

"I have severe and agonizing restless legs syndrome. People say it's because of my schizophrenia medicines, but I know it's genetics. I went through agonizing years until I found that taking tramadol every day completely cured it."

• jac...
• March 2, 2011

"I am unaware of any severely adverse reactions regarding the use of Tramadol. I use 50 mg two to three times per day for arthritic pain and for restless leg syndrome. I have also found that the more you use your back and legs during the day (exercise, walking, biking, running), the less symptomatic the restless legs syndrome is. Perhaps there is a connection between the neurological pathology of RLS and exercise. Maybe the increase in endorphins caused by exercise has something to do with it. Sorry, I digress. In the meantime, when RLS is symptomatic, Tramadol is a godsend. Tramadol is quite effective as well for arthritic pain. I wouldn't take anything else."

• bry...
• Taken for 2 to 5 years
• December 15, 2014

"I tried everything to stop this RLS, and nothing worked. I would be up all night moving my legs up and down, and then it started moving to my torso, and I could not take it no more being up. I was finally given tramadol for my back issues but found it worked to quiet my RLS. I only get 50 mg, and I live normally now with it. I can't tell you of the sleepless nights I have had without it. I only take one in the morning and one in the evening. It lasts for me, but sometimes it doesn't for real long periods of time. I would rather take tramadol than gabapentin, that is horrible! I also have nerve damage from my diabetes, and it also relieves that pain, too. Thank God for this to regain my life back."

• JAH...
• Taken for 6 months to 1 year
• June 29, 2020

"I have had RLS for over 50 years. It became 'out of control' over 10 years ago, and I began taking medication for it in 2009. I took Ropinirole for years, but gradually had to increase the dose until I was taking 2.5 mg. I was afraid to continue increasing the dose because what would I do when I reached the limit? My PCP finally sent me to a neurologist, and I was prescribed Horizant. That was like a miracle drug, and for about 9 months, I was good with Horizant 600 mg and Ropinirole 2 mg. A few months ago, the symptoms became worse again, and I had many sleepless nights. I called the neurologist and explained my symptoms. I told her that when I took Tramadol for back pain, it also stopped the RLS. I now take Tramadol 50 mg along with the Horizant 600 mg and Ropinirole 2 mg. I'm wondering if, when taking Tramadol, it is possible to reduce the Ropinirole and/or the Horizant? Any suggestion would be appreciated."

• ccf...
• Taken for 10 years or more
• December 15, 2016

"I have severe RLS. I tried Requip, Mirapex, Neurontin, Lyrica... Like many others who have posted, I had a pinched nerve in my spine (upper back, near my neck) and was prescribed tramadol. It greatly improved my RLS!! It truly was a godsend!! I do have to take 100 mg three times a day. And, if I take it too late, I do have to wait for an hour or so for the symptoms to finally diminish. Also, I have some daytime sleepiness, sluggishness. And now that my pinched nerve has become inflamed again, I have severe RLS even while taking the tramadol. I am hoping that after having a spinal injection for inflammation, my symptoms will improve once again. Until then, here I am, up with the rest of you, enduring this aggravating condition."

• che...
• February 11, 2012

"When I was in 8th grade, I fractured my back, and have re-fractured it 2 more times since then. I have done everything under the sun to help relieve my back pain, and the only thing that has ever worked has been Tramadol. I also have restless leg, and it is not just when I'm sleeping - it's all day, every day, and all through the night. I used to take the Tramadol to help this, and it completely cured the restless legs syndrome."

• Lyn...
• Taken for 10 years or more
• November 27, 2023

"I was prescribed Tramadol after my double bypass surgery 18 years ago. For the first time in my life, I was able to get a restful night's sleep. Previous to that, I suffered terribly with Restless Leg Syndrome. Months after my surgery, my heart specialist took me off Tramadol, claiming it was a medication he could no longer prescribe because it was on the opiate list (or some government list). My RLS returned, and I was once again unable to get a good night's sleep. Well, I am now back on Tramadol 50 mg/once in the evening, and am sleeping well again!"

• Red...
• Taken for 5 to 10 years
• March 22, 2016

"I also had suffered as a child with the leg movement, also was told growing pains, and as an adult, as I still had it, I would pour alcohol on it and take Tylenol and in 20 minutes it was gone, and didn't come back for a few days. As I got older, this has gotten so much worse, and if you ever need a Benadryl pill, Lord help you because it intensifies the problem tenfold. The tramadol helps a lot, two pills a night used to be three, but now I'm on buspirone for serotonin levels, and read that tramadol raises the serotonin. That's why I take only two now, but it still works good to control the RLS."

• Nom...
• June 17, 2017

"I have been on it for years for my peripheral neuropathy/restless legs. The tramadol manufactured in Asia is mostly junk. My Dr. recommended a pharmacy that orders a name brand generic form that works well for me. They are round tablets, the capsule-shaped are not as good. The cheap stuff makes me agitated and restless. I take two 50 mg tablets at bedtime (100 mg). It gets rid of my nerve pain caused by type II diabetes. My wife says I don't kick her anymore at night. I wake up feeling euphoric and ready to take on the day. It is frequently prescribed off-label as an antidepressant. No, it does not work well on back or muscle pain. Take ibuprofen for that. Motrin 800 works well for back pain. You can take the two drugs together."

• arm...
• Taken for 2 to 5 years
• September 27, 2016

"I was prescribed this for disc pain and spinal stenosis. I realized it helps my RLS. I usually only take it for back pain 2-3 mornings a week. If I have a pain-free week, my RLS flares up, and I take one, and in 30 minutes, I'm good. I DO NOT have to take it 2-3 times a day every day. I have had RLS for 30 years and only found relief once I hurt my back 4 years ago."

• OLD...
• April 17, 2011

"I have tried everything for this restless leg syndrome since the middle of the 1970s, nothing has worked. Even my pain medicines that I take now for serious pain. But over the years, no matter what was given to me for the restless leg syndrome, it did not work until I was prescribed tramadol for some back pain after I gave birth to my daughter, and I can say this much: I have never woken my husband up in the middle of the night since I have taken them, and I will never stop. I have had this problem since I was 8 years old. We all get to sleep peacefully now, and my legs have never felt better. And no, I do not smoke or take the pill."

• DAB...
• September 10, 2016

"I am taking 450 mg of tramadol per day, 250 in the morning and 200 in the evening. It works most of the time on a crumbling spine, but I have stopped getting RLS. I have been on them for about 15 years now, sometimes they don't touch the lower back pain."

• Anonymous
• Taken for 5 to 10 years
• February 20, 2025

"For many years, tramadol is the only thing that works for RLS. The ONLY thing. I've tried every other medication recommended for this. Cutting out sugar and exercise helps, but nothing takes away the RLS completely... only tramadol. It works best when taken about dinner time. It takes about 2 hours to kick in. Life saver. No side effects I'm aware of."

• Liz...
• April 9, 2010

"I was given tramadol after breaking my leg quite badly. At the time, the pain was so severe lower-strength painkillers wouldn't have been enough, but I've now been left with an addiction to tramadol, where I've been withdrawing gradually over months, and it's now left me with a bad case of Restless Leg Syndrome! To anyone who has never had this, it's a horrible feeling where you can't rest or sleep properly because of the horrible feeling going through your legs. It feels like someone is tickling the inside of your leg, and you can't sit still! I haven't slept properly in months now!"

• Anonymous
• May 30, 2010

"I have Restless Legs Syndrome, and it has a major impact on my life. Tramadol (generic) has really helped my RLS. It takes quite a while to set in, but then lasts for a whole day or more due to its long half-life. It does keep me up a little later than normal, but I feel much more relaxed and without the RLS at night. I think it is a good medicine when taken as prescribed and with regular check-ins with your doctor regarding dosing. If you have side effects, hang in there for a few days and they will mostly subside."

• Jer...
• Taken for 10 years or more
• October 13, 2019

"I am a 62-year-old male who suffered from RLS since my youth. I tolerated it until I reached my mid-40s when I finally had to see a doctor who sent me to a neurologist who diagnosed me with RLS. I was prescribed many of the typical RLS meds to no avail. I got no relief until he prescribed Ultram/tramadol. I have been on it for over 15 years and keep my dosage as low as possible, currently 250 mg a day. Tramadol relieves my symptoms if I take it early enough. Caffeine also helps me. Recently, I heard that some people use diclofenac sodium for RLS. There is some evidence from the UK that this may provide relief. I would like to find another medication to alternate with the tramadol because of augmentation."

• Mik...
• Taken for 5 to 10 years
• November 15, 2017

"My story is just so similar to so many on here. I have had severe leg pain in my calves since I was about 10. I would wake up crying, and when presented to a doctor, I was told they were just growing pains. In my early 20s, it got much worse. The pain was unbearable, and the RLS drove me crazy with the not sleeping, I was losing my mind. I was given some tramadol after some dental work and immediately felt the effects of the pain being gone, and the shaking and twitching was completely gone. I noticed that when I stopped taking it, by the next day the pain and twitching would return. My doctor had no problem prescribing it until they made it a controlled substance."

• MJ ...
• April 8, 2016

"Sleep deprivation from RLS was becoming unbearable. One 100mg Transform 2-3 hours before bed, and I slept like a baby for 4 months. Now my bigger concern is, am I hooked on this? I stopped cold turkey a week ago, and it's finally out of my system, but the withdrawal symptoms were horrible at night. Now I am back to sleepless nights and sluggish days. I would get back on it in a heartbeat so I could sleep, but am going to ask my doctor about non-opioid first."

• Jud...
• Taken for 2 to 5 years
• November 18, 2023

"I have had RLS since I was a teenager and it gradually got worse until it was intolerable, and I started on medication at the age of 58. Mirapex with gradually increasing doses worked for a number of years. However, the episodes of RLS gradually began to last longer and occurred 24 hours a day, accompanied by a violent jerk of my legs and/or arms. I was given every medication prescribed for RLS. For a while, I was on three medications, including a transdermal patch, with no relief. Three years ago, I started taking Tramadol 100mg three times a day, and it was an absolute miracle. I got my life and my sanity back. I also continue to take Mirapex 0.5mg four times daily. I have occasional brief episodes of RLS that resolve with walking for a few minutes, so now I can sit for long periods for a movie or concert, and I can sleep at night. The only side effect I experienced with tramadol was a dry mouth for the first few months when I first started on the medication, but that resolved, and I have no side effects now."

• sah...
• Taken for less than 1 month
• September 7, 2015

"I recently started taking 50 mg of Tramadol at night for severe RLS. I have been reading the horror stories associated with Requip as well as Tramadol. I am hoping that 350 mg of Tramadol over the course of a week will be too small of an amount to develop a dependence on, but who knows! Has anyone else been able to find relief for RLS by taking a small dose of Tramadol?"

• Anonymous
• March 15, 2011

"Works great for restless legs and back pain, and agreed, so what if you need to be on it forever. I need to be on Synthroid forever, and Premarin forever too. If it helps me sleep good at night, so be it."

• jef...
• April 19, 2009

"Since starting Tramadol 2 years ago (300 mg daily), I've been symptom-free from restless leg syndrome with no side effects. Prior to Tramadol, I experienced acute pain in my legs when inactive during the evenings. A sleep study also revealed moderate leg twitching during sleep, which interfered with REM. I was prescribed Requip 4 mg but had a couple of very bad reactions (sudden onset of acute sweating and nausea). I also take Tramadol for mild chronic back pain. Breakthrough pain can occur due to the relatively low strength of Tramadol compared to other prescription pain relievers. However, it's more accessible due to it being a non-narcotic, non-scheduled drug."