Mounjaro and Constipation: What Users Say (Page 4)

• Dia...
• Taken for 1 to 6 months
• December 25, 2024

For Weight Loss (Obesity/Overweight) "Started 5 mg 2 weeks ago and am doing great. Appetite significantly decreased. Have so far lost 11 lbs. and have 35 lbs more to lose. Constipation is my only concern. Working on that, but since I am not eating as much, I don’t think I will go as often. Grateful for this drug. It provides an easy way to lose weight. Thanks."

• Lad...
• Taken for 6 months to 1 year
• April 25, 2023

For Weight Loss (Obesity/Overweight) "I started taking Mounjaro on September 1, 2022. My starting weight was 192 lbs, I'm 38 years old and 5'3". By February 2023, I weighed in at 135 lbs. I experience severe nausea, sour stomach, sulfur burps, and constipation on every dose I was on. I was only able to go to 5 mg, as 7.5 mg about done me in. I went back to the 5 mg. I've always been active, worked out, etc., but after a few life events, I struggled to lose 10 lbs! This was a game changer for me. It quieted the food noise, the cravings, etc. I was able to eat just a few bites of whatever meal and then done. I didn't want to eat! My nighttime snacking is gone. I didn't even like the smell of McDonald's french fries. Now, my mom tried it also, but she never had any of the horrible symptoms, and the food noise quieted a little bit. She got up to 7.5 mg but couldn't get anything in stock for the 10 mg. She didn't lose the significant weight that I did and has now switched to Ozempic due to stock issues."

• SBu...
• Taken for less than 1 month
• March 30, 2023

For Type 2 Diabetes "It's easy to use, however, the side effects are horrible. I have had all of the listed side effects. Constipation, nausea, and vomiting are the worst. It feels like a rock in my gut, however, it's a little better than Ozempic, which I puked every day. So I'm sticking with the Mounjaro for now."

• Hap...
• Taken for 1 to 6 months
• April 10, 2023

For Type 2 Diabetes "Mounjaro has been wonderful in reducing my blood sugar. However, the side effects feel like sometimes they are going to be the death of me. I experience nausea, constipation, and stomach pain. But if this is how it has to be to control my sugar, I can handle it. The only real trouble I am having is being able to get it through my pharmacy as it is often out of stock due to people using it for weight loss. I think diabetics should be given the first chance to receive this medication."

• Ano...
• Taken for 1 to 6 months
• June 2, 2025

For Type 2 Diabetes "It has been great! My A1C has gone down, I'm using a lot less insulin, and losing weight. I've lost weight slowly, but the other benefits have been great! The symptoms I have experienced are fatigue, loss of appetite, changes in the taste of food, constipation, and hair loss. The hardest part is the price of the medication. It has fluctuated from $25 to $365. Not knowing what I am going to pay month to month has left me in a bind. I am really frustrated because I am getting priced out of a medication that is obviously helping me but not affordable."

• Alb...
• Taken for less than 1 month
• May 17, 2024

For Weight Loss (Obesity/Overweight) "Many friends have had various reactions to the shots. One had severe cramps and stopped using. In a couple of weeks, the cramps went away. I am on 2.5 going into my 4th week. I get some stomach gurgling, but the main reaction is constipation. I was very regular before usage. I use OTC drugs to manage the problem. After the 4th week, I am going on 5.0. My weight loss so far is 7 lbs. I started at 219. To go along with the shots, I put myself on a low-carb diet. Lots of protein and fiber."

• Kat...
• Taken for 1 to 6 months
• December 4, 2024

For Type 2 Diabetes "I had previously taken Byetta, Ozempic, and Trulicity. With each, I maybe lost 10-12 pounds. I started Mounjaro on August 1, 2024. I weighed 195 pounds. Four months later, I have not had any nausea. I do have some tiredness and constipation. As of December 1, 2024, I have lost 32 pounds. Hope to continue for at least four more months. Would like to lose another 20 pounds if possible. Hope to find a way to keep the weight off! Feel so much better. Was wearing size 16-18, now 12-14! My A1C went from 7.4 to 5.7!! Best news!! All other blood work numbers improved, especially cholesterol. I have very little craving for sugar or meat but try to eat at least four ounces of meat per day!"

• Anonymous
• Taken for 6 months to 1 year
• June 5, 2023

For Weight Loss (Obesity/Overweight) "I have lost 87 pounds in 9 months. I don't take blood pressure medication anymore and am not pre-diabetic any longer. I do have problems with constipation and some minor nausea the day after taking the injection. Overall, this medication has changed my life."

• lha...
• Taken for 1 to 6 months
• June 6, 2023

For Weight Loss (Obesity/Overweight) "Lost 37 lbs in 33 days (4 shots of 2.5 mg and one 5 mg). Now only lost 2 lbs over the last two weeks at 5 mg. I have a lot to lose and guess my body just needed a break. The weight was melting off like butter. No real side effects to speak of except first-week constipation and feeling a little sick if I eat something a bit fatty or greasy. So, I just cut that stuff out. Hopefully, I will start losing again on 7.5 mg."

• Mae...
• Taken for 1 to 6 months
• May 26, 2023

For Type 2 Diabetes "I am currently taking Mounjaro for type 2 diabetes. I have had much better success controlling my ups and downs on my blood sugar (BS), and even when I had a few celebratory drinks the other day, I’ve had no low incidences of BS. My A1C was 6.6 when I started, and it has gone down steadily. I’m also impressed with my weight loss, which in 13 weeks has gone from 245 to 218, and I am 5’4.” My initial side effects were occasional nausea and constipation. I just started my 7.5 dose 5 days ago and have noticed a decrease in constipation-thankfully! I saw another review saying they had sulfur burps and that this was a medication too good to be true. I disagree. I’ve no doubt that person had a tough time, but it has worked wonderfully for me! This is why it’s important to take this with the guidance of your doctor-this may not be for everyone-but I’m extremely grateful for this medication."

• Gra...
• Taken for 6 months to 1 year
• October 14, 2024

For Type 2 Diabetes "PROS: easy delivery system; decreased/normalized A1C; significant weight loss; improved daily glucose numbers; improved mobility; improved breathing/sleep apnea. CONS: SEVERE constipation (have a simple, daily 'bowel maintenance' plan with doctor to address this; works well); loss of muscle mass; pen disposal/recycling. Age: 45-54. Gender: Female. Race: African American. Start weight: 239. Current weight: 205 (down 6 sizes: 20 to 14). Height: 5'4''. Start A1C: 6.6. Current A1C: 5.3. My A1C is under 5.4. Started at 2.5 mg; increased to/stayed at 7.5 mg over 8 months to avoid losing weight faster than my skin could retract ('Ozempic butt'). I exercise 4 days a week; primarily weight training. I do an annual DEXA scan to evaluate my body composition (out of pocket). I've lost muscle mass using Mounjaro since my last annual DEXA scan (down 7 lbs of muscle, 34 lbs of fat). The muscle loss was really surprising and disappointing, since I always use weights (up to 60 lbs for leg exercises) when working out."

• jan...
• Taken for 1 to 6 months
• October 26, 2024

For Type 2 Diabetes "I started 2.5 Mounjaro on 9/10/24. I lost 10 lbs in a month. I was taking Humalog at meals and Toujeo at night. I was using very little insulin because I would have low blood sugar if I took even half of my usual dose of Humalog. I had minor side effects, such as constipation and some gas pains. I took Gas-X and laxative as needed. Very little appetite. After 4 doses, my doctor increased my dose to 5 mg. After 2 doses, I am not taking any insulin and my average blood sugar is 134. I have lost 16 lbs and eating small meals. I feel full all the time. If I eat too much, I feel miserable. My side effects are still minor. Some gas at times."

• Amy...
• Taken for 1 to 6 months
• October 21, 2024

For Weight Loss (Obesity/Overweight) "I’ve lost about a pound per week, starting with the smallest dose and leveling up every month. I started at 187 pounds and am down to 172. Side effects: constipation, belching, and fatigue (probably due to not eating enough). I like the pens and got over my fear of the needle. Sometimes it leaves a red welt in my tummy, but not usually. The worst part about it is the cost. My insurance doesn’t cover it, even though I was obese, had pre-diabetes, and sleep apnea (which I didn’t have when I was thinner). Imagine how many health issues could be solved if people could use this to lose weight."

• Spe...
• Taken for 6 months to 1 year
• October 21, 2024

For Type 2 Diabetes "This medicine works really well in reducing my diabetes numbers, and it has helped to reduce food noise. I have lost about 25 pounds in the last 8 months; however, I just started working out 2 months ago. The only side effect I experience is some nausea and/or constipation, which sometimes occur 24-48 hours after injection and only last for about a day or so. I sometimes take a fiber supplement if I experience constipation. This medication has helped me, and I no longer take any other medication for my diabetes, and my labs have greatly improved."

• Mag...
• Taken for less than 1 month
• May 6, 2025

For Weight Loss (Obesity/Overweight) "I am on my 4th week of 2.5 mg. Mild side effect of constipation, which I have managed with diet. Definitely reduced appetite, no desire to eat the usual chocolate, ice cream, or crisps, or late evening snacking. Then, a day after my 4th injection, I was, for the first time, suffering with wind, including the dreaded burps. Very little appetite. That was followed by a very bad bout of diarrhea, which saw me rushing to the loo all through the night. Settling down now after 24 hours. Not eaten today yet. Hoping this won't happen again, especially as I am due to increase dosage to 5 mg next week."

• Ano...
• Taken for 1 to 6 months
• April 29, 2025

For Weight Loss (Obesity/Overweight) "My wife has been taking it since January this year and has lost just a hair over 50 lbs. It has done very well for her and the weight is staying off. The only side effects noticed so far are that it makes you very gassy, somewhat indigestion, and every now and then a little constipation."

• Gar...
• Taken for 1 to 6 months
• April 5, 2023

For Type 2 Diabetes "I finished the first four weeks of 2.5 mg injections last week. Tonight, I start taking the 5 mg injection. I have had dizziness and lightheaded episodes that come and go, and occasional blurred vision. Constipation has been a problem. When I have dizzy spells, the top number of my blood pressure is lower than normal. My appetite has changed, I don't eat as much as I did before, and my weight has dropped thirteen pounds since I first started taking it. I see my doctor in two months, that's when I'll find out if it is helping my A1C. My doctor informed me that it would help me lose weight, which I need to do very much. It's very easy to use."

• Orl...
• Taken for 1 to 6 months
• September 9, 2024

For Weight Loss (Obesity/Overweight) "Lost 60 pounds in 4 months. Stomach pain and alternating diarrhea and constipation. I had recently been diagnosed with type 2 diabetes with an A1C of 6.6. Now my A1C is down to 5.5. My sleep apnea went from 27 incidents per hour to less than 2 per hour. I just started taking the 10 dosage. Every time I up my dosage, I have a few days of bad side effects, especially stomach pain, but after a while, they lessen, however, diarrhea or constipation never stops."

• Ano...
• Taken for 1 to 6 months
• April 9, 2025

For Weight Loss (Obesity/Overweight) "I have been taking medication for 16 weeks and lost 35 lbs. I have had some problems with stomach issues, but they come and go. I have had some constipation and diarrhea with the increase and the start of taking the medication. Sometimes it can be bad, but for the most part, I feel like the med is working."

• Anonymous
• Taken for 1 to 6 months
• July 22, 2024

For Weight Loss (Obesity/Overweight) "I am on my 4th week of Mounjaro. It is suppressing the food chatter in my brain really well. I am only eating when hungry. I do have increased constipation and am working through that. There is an achiness in my stomach that is not intolerable, just a nuisance. Intermittent nausea, no vomiting, no diarrhea. 2.5mg weekly. I lost 7 pounds starting the 3rd week."

• N R...
• Taken for 1 to 6 months
• July 4, 2024

For Type 2 Diabetes "I have started with 2.5 mg dose once every week on 16th April 2024. They gave me 4 rounds of this dose. Then they started with 5 mg dose once every week. Initially, I was feeling nausea, diarrhea, sour burps, and dizziness, and gradually it decreased. When I started to take 5 mg, the same symptoms, apart from diarrhea. This time I had severe constipation on the 3rd day of the 5 mg dose, but I took some home remedy and laxative medicine. Still experiencing constipation. But the good thing is my appetite has reduced significantly, I am eating like a 5 to 10-year-old child. Feeling energetic, I lost around 6 kg in weight. Sugar level is under control, reduced Humalog dose."

• Lis...
• Taken for 6 months to 1 year
• March 28, 2025

For Weight Loss (Obesity/Overweight) "When I weighed 212 lbs at 5’1”, I was facing breast reduction surgery, A1c was over 8, I was on Metformin and on multiple antidepressants. My doctor started me on Mounjaro at increasing doses. Now, just about 8 months later, my A1c is 6, I no longer need Metformin and I currently weigh 135 lbs…I’ve lost a whopping 77 lbs! I feel great! The side effects have been… little to no appetite, nausea for two to three days after injection, constipation… all easily managed. Mounjaro has changed my life, and I would do it all over again!"

• CMc...
• Taken for 1 to 6 months
• June 30, 2024

For Weight Loss (Obesity/Overweight) "Been taking 0.3ml weekly for nearly 8 weeks. This stuff works! Hunger dissipated and smaller portions eaten. Constant weight loss over that period up to 5kg (haven't checked in this week yet). My side effects are severe reflux (usually on the same day as injection) but can happen rest of the week and constipation. I do suffer from reflux from time to time prior to this, but it is definitely amplified with Mounjaro. All in all, very happy with the outcome."

• Ano...
• Taken for 6 months to 1 year
• March 29, 2025

For Type 2 Diabetes "Been on Mounjaro since April 24. Started on 5 mg because I was on Trulicity, which gave me severe stomach pains. Was on 10 mg before weight loss started. I’m 5’0”, lost 46 lbs, and A1C is 5.8. I now take 7.5 mg to avoid more weight loss. Hoping this will be my maintenance dose. Had very mild side effects initially, now just a little constipated, but coffee cures that. Feel better about myself. Very happy. Wish this came out years ago. Been diabetic since 42. Was unable to control both for a long time. Now I’m 68, and Mounjaro has made a believer out of me. I tell everyone about it that will listen. It affects everyone differently, so don’t always listen to the naysayers. Try for yourself."

• Typ...
• Taken for 1 to 6 months
• June 27, 2024

For Weight Loss (Obesity/Overweight) "Have been on Mounjaro 4 months now. First month I lost 12 pounds, then 2nd & 3rd month only lost 3 pounds each month but because of shortage I was unable to go up in dose. 4th month (on 5 mg now) I have lost 5 pounds (this month) for a total of 23 pounds in 4 months!! I’m thrilled just to be going in the right direction. PLUS I have only had minor side effects. Some nausea first 2 weeks & again for that long once I went up in dosage but manageable. Also, remember to have enough fiber to avoid constipation which bothered me a little. I have several chronic pain illnesses that do not allow me to move around much so I was never able to lose weight in past years without exercise. This is the first time. I am so THRILLED. Hoping I can stay on it to lose 70 more pounds! At least I have hope now!! Will continue to try. Hope others find hope with this drug."