Mounjaro and Constipation: What Users Say (Page 3)

• Ano...
• Taken for 6 months to 1 year
• March 31, 2025

"'This medication is a miracle. I’m a 53-year-old female. I never had a problem with my weight until after the age of 45. During COVID, I gained 30 pounds and got up to 170. I was exercising regularly and trying to eat healthy, but could not lose any weight. I started Mounjaro and lost 10 pounds the first month. I had very few side effects. The only thing I experienced was constipation. Once I became used to the medication, I realized that my neck tension and migraines were gone. I’ve been on the medication for 6 months, taking only every other month, and have lost a total of 40 pounds. I’m now at 134 pounds. My goal weight is 130. I feel AMAZING. This medication has been life-changing. I've not only lost weight, but it also regulates my fatty kidney, taken away migraines, and helped with anxiety."

• Lif...
• Taken for less than 1 month
• August 9, 2024

For Weight Loss (Obesity/Overweight) "I was recommended weight loss pre-knee surgery and decided to try Mounjaro. I am a 55-year-old female, at least 12 kilos overweight. I have been using it for 3 weeks now (2.5 mg) and have lost 2 kg. There was no nausea, and I manage slight constipation with poached pears and yogurt or a prebiotic. I realized very quickly that I needed to eat smaller amounts more regularly as opposed to my previous habit of waiting until I was really hungry - I didn’t eat badly before, but my food portions were larger, and I regularly consumed alcohol. I tried a sip of champagne after 2 weeks of Mounjaro, and it tasted horrible. The combination of eating less, feeling satisfied, sleeping better, and weight loss has already changed my life for the better."

• ARV...
• Taken for 1 to 2 years
• February 11, 2025

For Type 2 Diabetes "It is excellent for control of Type 2 diabetes. Fasting glucose stays below 100 mg/dL exactly for one week. Appetite is suppressed completely. The only side effect that is very troublesome is constipation with secondary discomforts. Regular laxative is the only way to counter this."

• Dav...
• Taken for 1 to 6 months
• February 9, 2025

For Type 2 Diabetes "I have been taking Mounjaro for 5.5 weeks. I've been on 2.5 mg the whole time. Although this dosage is considered a starting dose and not a therapeutic dose, I have seen a drop in fasting blood sugar from 110 down to 60 (I'm also taking metformin and glipizide). I have had few negative side effects (mild constipation) and have lost 8 lbs. I will talk to my Endo about moving up to 5.0 next and try to start reducing my metformin and glipizide dosages. Note: Although some people have some other major side effects, this drug affects everyone differently. You don't know how until you try it - this includes increasing your dosage."

• Ano...
• Taken for 6 months to 1 year
• March 29, 2025

For Type 2 Diabetes "Been on Mounjaro since April 24. Started on 5 mg because I was on Trulicity, which gave me severe stomach pains. Was on 10 mg before weight loss started. I’m 5’0”, lost 46 lbs, and A1C is 5.8. I now take 7.5 mg to avoid more weight loss. Hoping this will be my maintenance dose. Had very mild side effects initially, now just a little constipated, but coffee cures that. Feel better about myself. Very happy. Wish this came out years ago. Been diabetic since 42. Was unable to control both for a long time. Now I’m 68, and Mounjaro has made a believer out of me. I tell everyone about it that will listen. It affects everyone differently, so don’t always listen to the naysayers. Try for yourself."

• Ala...
• Taken for 1 to 6 months
• August 19, 2023

For Type 2 Diabetes "I started with 2 1/2, went up to five, and then now I am at 10. I lost a few pounds a week, although my appetite is much less than usual. The side effects have been very minimal, mostly headache, sore throat, and hoarseness seems to linger, never really goes. Constipation can be an issue at times, that only for myself, but other people I know on the same drug. My PA is working very closely with her and paying attention to absolutely everything closely. I feel that it’s a safe drug so far if you have a doctor or PA that is on board with you and to a full degree of attention. My hope is that once my A1c is in order, I will be able to discontinue the drug completely, although some studies recommend that not to be probable, again, working closely with my doctor and care team. Thank you for your time."

• Lis...
• Taken for 6 months to 1 year
• March 28, 2025

For Weight Loss (Obesity/Overweight) "When I weighed 212 lbs at 5’1”, I was facing breast reduction surgery, A1c was over 8, I was on Metformin and on multiple antidepressants. My doctor started me on Mounjaro at increasing doses. Now, just about 8 months later, my A1c is 6, I no longer need Metformin and I currently weigh 135 lbs…I’ve lost a whopping 77 lbs! I feel great! The side effects have been… little to no appetite, nausea for two to three days after injection, constipation… all easily managed. Mounjaro has changed my life, and I would do it all over again!"

• Joh...
• Taken for 1 to 6 months
• June 20, 2024

For Weight Loss (Obesity/Overweight) "Lost 10 kg in 3.5 months with daily exercise and a calorie-controlled diet. It does not eliminate the cravings, though, I always have them. Just needed the mindset that this is an expensive drug and I have to make it work. No side effects at all compared to what I experienced with Saxenda. Saxenda gave me the most horrible constipation I've ever had in my life. I genuinely thought I was gonna end up in A&E for impacted stool. I'm very happy with Mounjaro."

• kat...
• Taken for 6 months to 1 year
• June 5, 2024

For Type 2 Diabetes "I started with the lowest dose for Type 2 diabetes. My A1C was 7.5. I immediately noticed I just wasn't hungry. Otherwise, no side effects. I have been on 15mg for several months now, except when I have to get a lower dose due to non-availability of the drug in my area. My A1C is now down to 5.6, and I have lost 87 lbs. I started at 325 lbs. I have some constipation, but it is manageable. I had noticed increased muscle weakness in my thighs, and I could barely walk without fear of falling. My doctor thought it was a lack of protein. After several days of high protein drinks, I felt much better. After a few weeks, I was back to normal. This is a great drug. I just wish it were more readily available."

• Hon...
• Taken for 1 to 6 months
• October 6, 2022

"I have been taking Mounjaro for 7 weeks. 4 weeks of that I was on the 2.5 mg dose and lost 15 lbs by the 4th week. The last 3 weeks I've been on the 5 mg and I've lost ZERO lbs. Seems kind of useless to take when you have all the side effects (constipation, diarrhea, bloating, gas, nausea, headache, severe fatigue) for 3 weeks straight with no weight loss. I am considering going off this medication, I think it was all just hype. I've also stopped having periods. 40 years old, SW 199, CW 185, GW 140. Also following website food/calories recommendations. I have no other disease, just obesity."

• Dia...
• Taken for 1 to 6 months
• December 25, 2024

For Weight Loss (Obesity/Overweight) "Started 5 mg 2 weeks ago and am doing great. Appetite significantly decreased. Have so far lost 11 lbs. and have 35 lbs more to lose. Constipation is my only concern. Working on that, but since I am not eating as much, I don’t think I will go as often. Grateful for this drug. It provides an easy way to lose weight. Thanks."

• Kay...
• Taken for 6 months to 1 year
• May 25, 2023

For Weight Loss (Obesity/Overweight) "I have been using Mounjaro for weight loss for 9 months. I have lost 90 pounds and have had very minimal side effects. Some nausea occasionally and constipation. I am so grateful to have been prescribed the Mounjaro, as I no longer have heartburn and have alleviated having to take omeprazole daily. My sleep apnea has improved, I no longer snore like I used to and no longer need a sleep mask. The aches and pains have decreased substantially, and I have more energy than I have had in years. I was pre-diabetic, and all of my labs have improved. I am hopeful to be able to continue with the prescription, however, I would be unable to afford the current copay. I fear if I have to stop, I will be back to my same obese status as I was a year ago. The medication not only curbs the appetite but also stops the 'food noise.' If you have this issue, this will totally make sense. If not, I envy you."

• RBj...
• Taken for 1 to 6 months
• August 29, 2023

For Weight Loss (Obesity/Overweight) "I started using Mounjaro in March 2023, with a 2.5 mg dose, for weight loss. I shifted to 5 mg after 2 weeks; I stayed with each dose for around 2-3 months. I lost 10 kg by August (6 mo.). I had a freeze in weight loss for 5 weeks, then I lost 1.8 kg in 2 weeks when I took 10 mg. In terms of side effects, I experienced them during the first weeks of every upgrade in dose; like nausea and sometimes vomiting, headache, stomach pain, constipation and diarrhea, laziness, body ache, mood change; the worst was with 10 mg. As I have urticaria, I experienced an allergy at the needle site after week 10, which resolved in 3 days every time. This week I have pelvic, vaginal, and lower abdominal pain similar to period pain, although I have been menopausal for 4 years! I am happy about the results with minimal side effects."

• Rwi...
• Taken for 1 to 6 months
• March 19, 2023

For Type 2 Diabetes "My A1C and glucose levels are great. I am not on insulin. Side effects are rotten. Nausea, GERD, constipation/diarrhea, headache, stomach pain, decreased appetite every shot lessens over the week. Had this with Ozempic and Trulicity too, but not as severe. I have seen no weight loss benefit despite a decent diet and moderate exercise 3-5 times per week. Other side effects I’m not sure are related: feeling of lump in throat, slight face rash, occasional blurred vision, tingling in hands."

• Kat...
• Taken for 1 to 6 months
• December 4, 2024

For Type 2 Diabetes "I had previously taken Byetta, Ozempic, and Trulicity. With each, I maybe lost 10-12 pounds. I started Mounjaro on August 1, 2024. I weighed 195 pounds. Four months later, I have not had any nausea. I do have some tiredness and constipation. As of December 1, 2024, I have lost 32 pounds. Hope to continue for at least four more months. Would like to lose another 20 pounds if possible. Hope to find a way to keep the weight off! Feel so much better. Was wearing size 16-18, now 12-14! My A1C went from 7.4 to 5.7!! Best news!! All other blood work numbers improved, especially cholesterol. I have very little craving for sugar or meat but try to eat at least four ounces of meat per day!"

• Aje...
• Taken for 1 to 6 months
• August 11, 2024

For Weight Loss (Obesity/Overweight) "The BEST EFFECT is that I was free from thinking about food for the first time in my long life. The downsides that I am still working with are being constipated, getting chills, and stomach pain. I have to take Miralax every day, and some days I do not feel well, and yet, it is well worth it to not be obsessed with food anymore. I am on 5 mg. I was concerned about self-injection but found that to be a non-issue. I do get a rash around the area, and my skin itches."

• Flo...
• Taken for 1 to 6 months
• June 1, 2023

For Weight Loss (Obesity/Overweight) "I began taking Mounjaro in November 2022. I am 61 years old, weigh 194.6 lbs, a post-menopausal female with no other health issues to note. Since then, I have lost approx. 50 lbs and feel absolutely GREAT! In addition to the Mounjaro, I took weekly B12 shots, a multivitamin, a magnesium supplement, apple cider vinegar capsules, and a chromium supplement. I took the last injection on May 2, 2023 (weighing 144.6 lbs) and have continued with supplements. After 1 month, I am weighing 146.4 lbs. I do find myself having cravings at times and could eat more, but have been able to discipline myself to continue to eat in moderation and try to be more active since I definitely feel more energetic. My goal is to maintain below 150 lbs. I am a huge fan of this drug and have experienced very few side effects while taking it. I did experience indigestion and some constipation relieved by the supplements listed above."

• Mik...
• Taken for 1 to 2 years
• February 26, 2025

For Type 2 Diabetes "This product has been excellent for me. My A1C came down from 8.9 to 5.9 in about 6 months. I have a few adverse symptoms: constipation, some stomach issues, but nothing I can’t live with, considering the alternative of out of control A1C. Plus, I’ve lost 55 pounds."

• Rev...
• December 29, 2022

For Type 2 Diabetes "I was prescribed this medication after having an ESG procedure to help with weight loss and in hopes of reversing Type 2. I also have PCOS and a family history of Type 2. After being on this medication, I am down at least 10 lbs (don’t remember my weight when I started), and my blood glucose is not in the diabetic range. My A1C was 5.9, down from 7.9, and I expect that to be lower on my next labs. I do have some side effects, the most prominent is constipation. Miralax helps. I used to get a headache after injection, but I take ibuprofen beforehand, and that helps. I also inject my thigh, not my stomach, and I do it before bed. I have to remember to eat and drink water. I would recommend this medication. I hope I’ve lost enough weight to get off and stay off. So far, so good."

• BLB...
• Taken for 6 months to 1 year
• May 29, 2023

For Type 2 Diabetes "I started Mounjaro in July '22 after losing 50 pounds (243 to 193, 5'2") on Trulicity. I am now closing in on losing 50 pounds on Mounjaro (approaching 143 lbs) and can honestly say that it has changed my life. My cravings for sugar are nearly gone. I drink 2 protein shakes each day and have found eating healthy and eating smaller portion sizes easy. I am a person who had horrible hyperemesis gravidarum during pregnancy, so I knew I would have the side effect of being nauseous. And I do become quite nauseous for the 2 days after the injection. However, I am able to manage this pretty easily as it passes quickly. Going from 12.5 mg to 15 mg was too much for me. I do best on the 10 mg. I do get minor constipation and occasional tiredness, but overall I feel 100 times better than I did 100 pounds heavier and I am no longer in the diabetic range."

• Anonymous
• Taken for 6 months to 1 year
• February 19, 2025

For Type 2 Diabetes "Severe nausea and stomach pain within the first 2 days of taking, then settles the next 5. Always feel a pressure in the stomach - not pain, not really uncomfortable, just a noticeable presence. Constipation for 4-6 days despite taking extra fiber and water."

• Fir...
• Taken for less than 1 month
• March 18, 2023

For Type 2 Diabetes "I am surprised by how quickly it has changed my appetite. My first injection of 2.5 mg was two days ago, and after a very small meal, I am completely full for hours. I’ve had constipation and feel bloated, or at least unpleasantly full. Hoping this will pass. I ate a bowl of turkey chili for dinner yesterday, and at noon today, I still have no desire (or room) to eat. I had a glass of water to take my morning meds and a cup of coffee this morning, and I’m still full."

• jan...
• Taken for 1 to 6 months
• October 26, 2024

For Type 2 Diabetes "I started 2.5 Mounjaro on 9/10/24. I lost 10 lbs in a month. I was taking Humalog at meals and Toujeo at night. I was using very little insulin because I would have low blood sugar if I took even half of my usual dose of Humalog. I had minor side effects, such as constipation and some gas pains. I took Gas-X and laxative as needed. Very little appetite. After 4 doses, my doctor increased my dose to 5 mg. After 2 doses, I am not taking any insulin and my average blood sugar is 134. I have lost 16 lbs and eating small meals. I feel full all the time. If I eat too much, I feel miserable. My side effects are still minor. Some gas at times."

• Amy...
• Taken for 1 to 6 months
• October 21, 2024

For Weight Loss (Obesity/Overweight) "I’ve lost about a pound per week, starting with the smallest dose and leveling up every month. I started at 187 pounds and am down to 172. Side effects: constipation, belching, and fatigue (probably due to not eating enough). I like the pens and got over my fear of the needle. Sometimes it leaves a red welt in my tummy, but not usually. The worst part about it is the cost. My insurance doesn’t cover it, even though I was obese, had pre-diabetes, and sleep apnea (which I didn’t have when I was thinner). Imagine how many health issues could be solved if people could use this to lose weight."

• Spe...
• Taken for 6 months to 1 year
• October 21, 2024

For Type 2 Diabetes "This medicine works really well in reducing my diabetes numbers, and it has helped to reduce food noise. I have lost about 25 pounds in the last 8 months; however, I just started working out 2 months ago. The only side effect I experience is some nausea and/or constipation, which sometimes occur 24-48 hours after injection and only last for about a day or so. I sometimes take a fiber supplement if I experience constipation. This medication has helped me, and I no longer take any other medication for my diabetes, and my labs have greatly improved."