Sodium hyaluronate and Soreness: What Users Say

• Beb...
• December 5, 2020

For Osteoarthritis "I had Durolane injection in both knees yesterday. I have a headache so bad. I feel sick to my stomach, my left knee is larger and hard from the top of my knee and down, he drained it yesterday as well. I don’t know what to I wish I didn’t get it. This is the worst feeling. If I feel the same tomorrow I will call the Dr's office again. My right knee is very sore. They feel like someone is hitting me in the knees with a hammer, not stopping? I hope it’s not a blood clot. I don't know. I can hardly walk. For me day 2 it’s terrible, thank you for letting me tell my experience"

• Ang...
• December 12, 2019

For Osteoarthritis "I got a Durolane injection on Tuesday. Just in the left knee. So glad I decided against getting both knees done. First day was okay. I had some soreness, but my pain continues to get worse each day. It is extremely difficult to get a good night's rest. I have difficulty walking. I was doing so much better prior to the injection. I did the one thing I tell everyone else: don't put your faith in the doctor because they don't know everything. I so wished I had done my research, then I would not be in this excruciating pain. No more of any kind of injections for me. I can deal with my normal discomfort. But this pain is almost unbearable. Do your research!!"

• TLP...
• Taken for less than 1 month
• November 4, 2014

For Osteoarthritis "I am 41 years old and have osteoarthritis in both knees. I have tried everything from steroid injections, medications, and physical therapy without any long-term relief. The steroid injections were really painful and didn't last, so I was very hesitant to try the Euflexxa. My Orthopedic Dr. gave me two choices (lubrication injections or arthroscopy). I knew that I didn't want the arthroscopy, so I went for the Euflexxa. I was terrified but needed some relief. My first injection hurt a little and my knees were sore for a few hours. My second injection hurt a little more and was sore a little longer than the first time. I will have my third injection in 2 days and can't wait. I am so glad that I did it! My knee pain is very minimal."

• Rit...
• Taken for less than 1 month
• July 18, 2019

For Osteoarthritis "I have bone spurs and osteoarthritis in my left knee. I am a candidate for a total replacement, however, I am trying to postpone surgery for as long as I can. My doctor recommended the 3-shot series. I had my first one yesterday. I have not had any side effects from it other than a little soreness where it was injected. I am hopeful that this will buy me some time."

• Anonymous
• Taken for less than 1 month
• October 8, 2019

For Osteoarthritis "Received my 2nd shot of Euflexxa following recovery from a broken tibial plateau that took way too long to heal and no major issues at all. Some tenderness after the injection, which is expected. Following instructions of taking it easy for a day or so is highly recommended. No side effects and immediate relief from osteoarthritis pain. Pain level decreased significantly after the 1st injection. Good alternative to invasive procedures and surgery. My experience may be different than yours."

• pal...
• Taken for less than 1 month
• June 9, 2019

For Osteoarthritis "I had my knees injected with Durolane on Tuesday, June 4th, 2019. I regret that I ever took this injection to both of my knees. I'm having pain in both knees, much worse than before. The first evening, I felt as if I was not able to walk. My legs and hips are aching. I'm so sorry I did this. Cortisone has helped me in the past and has never caused this kind of pain. The first night, I sat up all night with ice packs and cried due to no relief. I took my prescribed pain medication, and still no relief. It is now 4 days later, and I am still experiencing unusual pain. I have taken Synvisc One in the past and never, ever had such a bad experience. I pray this pain will subside in time. NEVER AGAIN WILL I TAKE DUROLANE."

• Ama...
• Taken for 1 to 6 months
• September 24, 2021

For Osteoarthritis "I had one-time injections into both knees due to osteoarthritis. I had tried OTC relief and prescribed gel without any help. Had both knees done in May 2021 at the same time. The procedure itself had no pain, just some mild pressure. I walked to the checkout and felt like a baby deer, slightly wobbly. That day I stayed iced and elevated, I was uncomfortable but not painful. I went to work the day after the injections, I regret doing that. I was stiff and sore, and I work in a clinic, so I am on my feet all day and kneeling down often. I had the weekend off, and they started to loosen up. After the first week, I was feeling good and had no pain after day 3. Fast forward to now (4 months post), and I have zero complaints. While I still have moderate crepitus in both knees that I hear going up and down stairs, I have no pain. Nothing to stop me from being active or doing day-to-day activities. I’ve recommended this to others and will gladly do it again when this dose wears off."

• Kat...
• Taken for less than 1 month
• October 5, 2021

For Osteoarthritis "I wish that I would’ve found this before my injection of Durolane. I had the injection on a Wednesday, and now it’s Monday. I have been in excruciating pain since. My Dr. said I would be sore for a few days and would be able to resume normal activities. I haven’t been able to do anything! They told me today when I called crying that it’s normal to give it a week. I’m not sure that I want him to do my knee replacement. This is just too much for me. I’m a busy person and feel terrible."

• Leb...
• Taken for 2 to 5 years
• December 18, 2021

For Osteoarthritis "Immensely helpful. I had arthroscopic repair of a badly torn meniscus. Six months later, I had a lesser tear in the other knee. I originally got cortisone injections several times. Then Durolane every 6 months and had three injections (in each knee) over 18 months. I then went 9 months without an injection, then again both knees. It is not a cure. But I cannot take NSAIDs, and Durolane has allowed me to remain active. I am not an athlete, nor do I run. I do, however, bicycle 20+ miles at a time with some soreness the following day. I can hike several miles, walk several miles. I pretty much am using it prophylactically. I do not wait until the pain gets horrible before getting injected again. That may contribute to my good response."