Semaglutide and Upset Stomach: What Users Say (Page 4)

• Sic...
• Taken for less than 1 month
• April 25, 2022

For Cardiovascular Risk Reduction "I started Ozempic last Wednesday. Nausea, upset stomach, and profuse vomiting. I’ve already gone to the ER for fluids last Thursday and now back today for more fluids. I know it’s going to improve my A1C, weight, and BP, but I’m not sure if I can go on this sick. I go back for my 1 week tomorrow."

• PDH...
• Taken for 1 to 6 months
• June 21, 2019

For Type 2 Diabetes "I started Ozempic about 3 months ago at .25 mg. My doctor made me start my 1st dose on a Monday in her office because I would tell her I would try and then never do it. Tuesday morning I was good, then by Tuesday night, stomach cramps, nausea, vomiting, and diarrhea, till the wee hours of the morning. The symptoms slowed down throughout the week. Even though I was losing at least 3-4 pounds a week, a total of 35 pounds within a 2 1/2 month period. My A1C did go down, the side effects are deadly. I like the fact that I am losing weight, but I hope I don't have permanent damage from this medication."

• Ang...
• December 11, 2019

For Type 2 Diabetes "It was good on low dosage 0.25, but after 2 months, it loses effect, and you need to increase the dose. Still fine, I lost 30 pounds, but then you have to increase the dosage, and that's when I got stomach aches and diarrhea, and I had to stop it."

• Kev...
• Taken for less than 1 month
• December 2, 2023

For Weight Loss (Obesity/Overweight) "It sure works. Even at the lower initial doses, it completely CURBS your appetite, and you are no longer hungry. It’s an interesting phenomenon. I’m going to have to plan means better and so forth. So far, side effects have been mild stomach upset and fatigue, but nothing substantially more…"

• Bub...
• Taken for 1 to 6 months
• August 28, 2019

For Type 2 Diabetes "I have been on Ozempic for 9 weeks. I have not increased my dose due to stomach issues, I just stayed at .25. My A1C is starting to come down slowly. Have a 3-month check-in in 2 weeks. It was 10.2, then dropped to 9. I do feel weak and dizzy, and I dropped low in the morning and at night. Sometimes in the middle of the day. Yes, I am bloated. My weight was 220, lost 4 lbs, and I gained weight, so then 222. I have lost weight and I am down to 217. Hope this weight loss continues."

• Liz...
• Taken for 1 to 6 months
• January 21, 2023

For Cardiovascular Risk Reduction "Ozempic has done nothing to help me with Type 2 diabetes nor weight loss. I have some stomach discomfort and some loss of appetite. My blood sugar levels are just as high with Ozempic as before taking Ozempic."

• sil...
• Taken for 1 to 6 months
• March 24, 2019

For Type 2 Diabetes "I've been on 1 mg of Ozempic for about 8 weeks and lost 13 pounds. My appetite has decreased. Other people started out at .25 or .5, I've noticed from reading other reviews. Considering this, I'm shocked my doctor started me on 1 mg. I was really sick the first month. Lots of vomiting, gas, stomach ache, and diarrhea. Despite all that, I'm pleased that I lost weight and the side effects have gone away. I just hope it continues to work as an appetite suppressant. Other meds I've taken that were originally one for me stopped working on my appetite after a while."

• wis...
• April 15, 2021

For Type 2 Diabetes "I've been on Ozempic for 7 weeks now: 4 weeks at 2.5 and half the usual insulin dose, followed by 3 weeks at 5.0 and no insulin, as instructed by my endocrinologist. I experienced leg cramps, stomach cramps, lethargy, and light-headedness among other symptoms in the first 4 weeks. My fasting sugar results increased. During my 3 weeks on the 5.0 dose, I have suffered feelings of nausea, regular bouts of light-headedness, and my fasting sugar levels are now up to the 14-17 range. My energy levels are decreasing. I am taking myself off this medication over the next 3 weeks. An interesting experiment to undergo but not worthwhile continuing as there are no benefits (except weight loss - and I can't afford to lose too much more weight) but light-headedness, lethargy, feeling like vomiting regularly, increased cramps, and, worst of all, my blood sugar levels going through the ceiling. Concentration levels are also a concern."

• Cpa...
• July 1, 2019

For Type 2 Diabetes "I've been taking Ozempic for six weeks. I'm experiencing a lot of the same side effects as everyone else. No nausea, but definitely the cramping, bloating, sore stomach, and constipation. Had to do two fleet routines already. Weight loss has been fantastic, but I'm beginning to worry now. Twenty pounds so far and still dropping. .25 mg dose. Sugar numbers have been great. Don't think it's worth all the side effects. Going back to Farxiga. Much more predictable."

• Poi...
• Taken for 1 to 6 months
• January 18, 2019

For Type 2 Diabetes "Started taking this med about a month ago and not sure I will stick with it. After 2 weeks, stomach cramping and some constipation started, but the worst of it all is the stress I am having with horrible sulfur burps. The smell is so horrible that even the smallest of burps can linger in a room for minutes, and you can really clear a room. I have had to have Febreeze Air Fresheners nearby at all times. If I feel a burp coming in the middle of the night, I literally run to the bathroom as it is really very unpleasant for my spouse and it really embarrasses me even after 27 years of marriage as it’s that bad! We just lowered my dose to 0.25 mg, but if the sulfur burps remain, that will seal the deal and I will stop it. Have lost 10 pounds over the month too as appetite is shot, and I’m not sure that’s really the best way to lose weight if you can barely eat at all."

• jwi...
• Taken for 1 to 6 months
• June 15, 2023

For Weight Loss (Obesity/Overweight) "I have been on Wegovy now for 4 months and have lost 26 pounds. I am currently on the 1.7 mg, and I have had no nasty side effects. I have had more heartburn than I used to, and occasional stomach upset, but nothing that would make me stop taking the meds. It has been a slow loss, but it is a loss, and I am very happy. I would love to lose 75-100 pounds, and hopefully this will continue to work, and I will meet my goal. My start weight was 250 lbs, I am now at 224 lbs. My glucose levels have decreased, and my A1C has also lowered. I have not been adding exercise, I feel if I started walking, the weight would come off faster. My overall experience has been very satisfactory."

• Hed...
• Taken for 2 to 5 years
• August 18, 2022

For Type 2 Diabetes "I’ve been taking Ozempic for about two years. I started at .5 and now at 1. The pros have been much lower A1c. I was at a 9.4, now it’s 6.2. I’ve also lost about 20 pounds… very much suppresses your appetite. I went from 175 to 155. I’m 5’8. So in that respect, it’s been great. However, I have had terrible nausea, especially the first 72 hours after taking it. Some stomach issues, especially that gagging feeling. I remain on it because of the A1c and weight loss, but I gotta tell you guys it’s been really rough. My husband is on a .5 dose, and he doesn’t seem to be having these issues."

• Juj...
• April 30, 2019

For Type 2 Diabetes "Today marks day 6 on .5 of Ozempic, and I feel like it is working. I have a severe insulin resistance problem and haven't seen my numbers down into the 100's in way too long. My problems with Ozempic are that I can't eat. I'll take a few bites of whatever and get very nauseous and then a tummy ache. I did gain 20 lb in 2 months with the insulin use and feel like I'm losing the weight with Ozempic, but I'm a little concerned that I'll gain it back fast later. Oh, and constipation was settling in, but the only thing I've wanted to eat are cold prunes! Hahaha! So, problem solved. Burps? No, unfortunately, I can't burp! I have the feeling of wanting to, but nothing. Anyone else?"

• Mar...
• Taken for 1 to 6 months
• March 19, 2021

For Type 2 Diabetes "I started Rybelsus with the 3 mg that the doctor gave me. Nausea started right away, but I could deal with it for the most part. When it was time to go to the 7 mg, I got scared of the thyroid cancer warnings and didn't continue with the drug. But my numbers started climbing after that again. So, a couple of months later, I started with the 7 mg that I had. I used it for a month, and the diarrhea, gas, and gurgling stomach increased each day. The diarrhea would wake me up in the middle of the night! I was having 5 to 6 bowel movements a day, I was afraid to leave the house. So, I saw the doctor and am going back to Trulicity, which I had fewer side effects with. I really wanted this medication to work for me as I need to lose a lot of weight. But the side effects are not worth it for me."

• Ano...
• Taken for 1 to 2 years
• June 3, 2025

For Type 2 Diabetes "The first year I started using Rybelsus I lost 14 lbs in about 6 months. The 7th month I experienced an extreme stomach ache that made me lightheaded, and I fainted. I was visiting my daughter, and she found me near the bathroom on the ground. I reduced use from 14 to 7 mg, maintaining the loss for 6 months and then gaining 8-10 lbs. I went back on the 14 mg dose. 3 months later, I had another episode with a severe stomach ache, lightheadedness, and fainting that totally scared my husband in the middle of the night. I am generally a healthy eater and pretty active, just weight loss at my age is difficult. I am going to manage my A1C without drugs now."

• She...
• Taken for less than 1 month
• June 20, 2018

For Type 2 Diabetes "The experience seemed to be consistent. I have Type II diabetes, and I'm trying to lose a little weight, actually a lot of weight. But I have chronic IBS, so when I started Ozempic and suffered bathroom issues, I wasn't sure it was the drug. But I started feeling really not great, stomach cramps, diarrhea, and even a little depressed? Two doses and I stopped. This is not for me..."

• Cee...
• Taken for 1 to 6 months
• March 2, 2022

"My daughter started on Ozempic for PCOS after Rybelsus didn't work. She was on .25 and didn't feel great but ended up feeling really terrible after two weeks. Throwing up every day, headache every day, dizzy, lots of stomach problems, acne breakout. Stopped the Ozempic 10 days ago (after a total of 4 shots), and she is still sick. Waiting for this poison to leave her system. It may work for you, and I hope it does, but it 100% did NOT work for my daughter."

• cju...
• Taken for 2 to 5 years
• July 7, 2024

For Type 2 Diabetes "Have been on this for about 2 years. Blood sugars were 11 before taking, now average about 6. Really need to watch how much I eat or will throw up. Blurry vision, stomach aches occasionally. Generally, this has been a great med for me, reduced the medications I was taking for diabetes. Now I take 10 mg Jardiance and 4 mg glimepiride. No more insulin!!"

• Cap...
• Taken for 1 to 6 months
• May 12, 2021

For Type 2 Diabetes "I took Ozempic last October, but I had to come off it - I was so ill. I'm type 2 diabetic and Hashimoto's thyroiditis autoimmune disease. I'm 57 years old and post-menopause. The doctor decided I should try again, I started 5 weeks ago and had my 5th injection. I have been sick since I restarted. I have nausea, vomiting, diarrhea, brain fog, anxiety, burning in my stomach, headaches, and I'm so tired and weak. I tried to stick with it, I'm on the 3rd day since my 5th injection. I am so ill, I still have all the above symptoms, but worse. My kidneys are sore and my lungs. I have pain in my stomach and back. I feel like my body is poisoned, and I have to wait for 5 weeks for it to clear out of my system. I will never take this again."

• Pop...
• Taken for 1 to 6 months
• October 12, 2019

For Type 2 Diabetes "I've been taking Ozempic for a while now. While it's working, I find I'm getting a lot of stomach discomfort and nausea, which I've put down to the medication! I'm willing to put up with it as long as it stays mild!"

• Ice...
• Taken for less than 1 month
• November 4, 2019

For Type 2 Diabetes "OMG ... it’s not me. Dr. started me at .5 of Ozempic, first day after injection pretty much okay, then came nausea, stomach ache, headaches, then just dulled, gassy (didn’t know the burps were part of it but that increased), diarrhea, feeling beyond blah. I went to work and struggled through the day for 4 days like this. The first week wasn’t sure if it was the shot or some food, so I tried the Ozempic again. The second week was a little better, so I decided I’ll try the smaller dose. Today is day 2, but this morn, there’s the nausea, stomach ache, a little bit of headache, but lesser amounts. Despite the thought of weight loss, might be heading back to Januvia (Farxiga got the yeast infection, but it was cheap, $15 for 90 with insurance)."

• Cat...
• May 9, 2025

For Type 2 Diabetes "Had problems with stomach issues when I first started it. Dropped the 7 mg dose down to 3 mg for 3 months. Then went back to the 7 mg. Now I’m on 14 mg with not as many GI problems, except I still had problems with bad constipation, so I add fiber supplements and more fruit and fluids. Doing okay so far. A1c better, weight down a few pounds, lab numbers are better. Thank you."

• Wah...
• Taken for 1 to 6 months
• August 10, 2019

For Type 2 Diabetes "I started taking Ozempic (semaglutide) five weeks ago to control my A1C, blood sugar, and weight loss, but I don't see any change. I got gas, bloated, stomach upset, and constipated. Out of the five weeks, three of them I got a UTI, and I am miserable. Going to see my regular doctor today because my endocrinologist who prescribed this medication is off during the weekend."

• Rea...
• Taken for 6 months to 1 year
• August 25, 2021

For Type 2 Diabetes "I've been on Ozempic for about 6 months now, and I've had the absolute worst gastro issues. I didn't notice it much at first, and when I went to my doctor a few months ago, he said it was just my IBS, but after reading these comments, I firmly believe it's the medicine. I have terrible diarrhea. I go at least 8 times a day, and that's no exaggeration. Awful stomach cramps, and I can't even pass gas anymore, literally, I shart. I'm weak and low energy. I've lost 20 lbs, but it's because I'm pooping it away. It helps curb my appetite, and my sugar is good and my A1C is down, but I can't continue this medication. It's truly affected my daily life. I can't go out anywhere that doesn't have a bathroom because when diarrhea hits, I have to go right then. So embarrassing. I'm hoping it's not caused any other issues! Just diet, people, don't take this medicine."

• Nan...
• Taken for 6 months to 1 year
• February 18, 2021

For Type 2 Diabetes "After reading the reviews, a lot of my problems using Ozempic have been answered. I was wondering why I had the side effects that I did, such as vomiting, diarrhea, bloating, stomach gurgling, and belching or egg taste, etc., but a lot has been answered here. My only comment about this is that I am to use .50 every week, and my pen only holds 3 weeks' worth. I have called 2X after I mentioned it to my nurse practitioner, and the only thing I get is offered a voucher for a free pen. My question is, am I the only one that doesn't get the full 4 weeks' worth of the pen if using .50? I tried to ask that to customer service this morning, and she could not answer my question but only offer yet another voucher. Please tell me if I am the only one that this happens to or not. Overall, I am extremely happy with the product."