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Rybelsus for Type 2 Diabetes User Reviews (Page 4)

Reviews for Rybelsus

Commonly mentioned side effects
  • Typ...
  • Taken for 1 to 6 months
  • April 5, 2022

"I was on Rybelsus as an add-on for my A1C control. This medication was okay at the 3 mg dose…for 2 weeks. Then when the dose was increased to 7 mg, I was nauseous every day, vomiting 4-5 times per week. I couldn’t eat, the mere thought of food or smell of food made me vomit. I ruined a day of vacation at Disney because I threw up 8 times in a 2-hour time span from this medication. It even began to interfere with my job (I’m a nurse-I can’t be throwing up multiple times a day). My A1C increased from 7.2 to 9.6 while on the medication, and I gained 8 pounds. I stopped taking it while waiting for my appointment with my provider, and I already feel 1,000 times better. I’m glad this medicine has worked for others, but I definitely don’t recommend."

1 / 10
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  • Lyn...
  • Taken for 1 to 6 months
  • December 18, 2021

"I took 3 mg for 2 months and then started the 7 mg. The 3 mg I had heartburn, nausea, some diarrhea. Was uncomfortable but doable. But once on 7 mg, I had the same symptoms plus vomiting, constipation to the point of hemorrhoids, and severe heartburn to the point I almost went to the ER. I got out the label on this medicine, Rybelsus, and relooked up side effects symptoms on the computer. I immediately stopped on my own, messaging my doctor. Within 2 days, I felt so much better. This medicine is costly too, luckily I had insurance because I will not use this and it had to be disposed of. $ wasted."

1 / 10
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  • Jes...
  • January 28, 2021

"I am a 38-year-old woman with lupus and fibromyalgia. I was on Farxiga 5 mg twice daily, and my sugars were crazy, my A1C stayed at a 7.4, and I was always hungry. My doctor put me on Rybelsus 3 mg, I’m on day 12, and I had nausea and bloating if I ate my normal way. If I ate in moderation, I was good. Haven’t seen weight loss yet, but I like how I’m not starving all the time and glad to see the bloating stop and nausea also. Great drug. Exciting to see the results. Oh, and in November, I was at an A1C of 7.4, and now it’s a 6.4."

10 / 10
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Frequently asked questions

  • Ano...
  • Taken for 1 to 6 months
  • December 11, 2021

"I started Rybelsus 3 mg, 7 mg, 14 mg. I was 190 pounds, and I am currently 170 lb. With zero exercise, it is expensive, but I had serious GI issues due to C. diff. I am now eating healthy, eating less, my BM movements are regular. Could not be happier. Yes, there was nausea, but you have to take this pill every morning at the same time on an empty stomach. I take it in the morning before my vitamin drinks and go back to bed for 30 minutes. Best medication ever."

9 / 10
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  • tuf...
  • Taken for 1 to 6 months
  • August 6, 2021

"I love my Rybelsus. My numbers are so much better. I can stay in my target zone for the 1st time in years. I'm excited for my next A1C instead of dreading it. No side effects at all except pure joy. 24-year type 2. Metformin and Glipizide. I was in the high 200s to 300s. Not anymore."

10 / 10
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  • Jac...
  • Taken for less than 1 month
  • December 24, 2020

"I am 70 and was diagnosed with type II diabetes about 7 years ago. I have always been on Metformin and have tried medications like Farxiga and Janumet, both of which give me bad leg pains after a while. I started Rybelsus, 3 mg, about 6 weeks ago, and after 3 weeks felt so bad I stopped taking it. The worst feeling was quite bad lower back pain and a sort of fatigue. It was a generally weird feeling of malaise, not just fatigue. So if an introductory dose of just 3 mg is any indication, a stronger dose would be terrible for me. So now I am on the max dosage of Metformin, and my last A1c was 7.6. 7 years ago it was 6.5. I would add that at most I have been about 15 lbs overweight, and there has never been any incidence of diabetes in my family."

1 / 10
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  • kit...
  • Taken for less than 1 month
  • August 2, 2021

"Rybelsus made me really sick. I didn't realize it until a couple of days ago. I thought I had a virus. I was practically leaning on the wall every day, trying to pull myself out of work to the car. Last week, I spent a lunch time lying on my office floor and then just left early. It is more than the nausea, it was fatigue, significant dehydration, confusion, dizziness, headaches... I'm still feeling sick after 2 days of not taking it. I just read that it can take a couple of weeks to get out of your system."

4 / 10
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More FAQ

  • Joh...
  • Taken for 1 to 6 months
  • March 7, 2023

"I started with the 3 mg. Within a week, my bowel movements became loose. Other than that, it was fine. Started the 7 mg after a month. Within a week, I was nauseated constantly, along with diarrhea. The nausea got worse, and diarrhea continued. At three weeks, I had to stop taking it. The very next day, nausea stopped, and I have normal bowel movements again. I do not recommend this medication. Also, vomiting was a relief a few times."

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  • Sti...
  • Taken for less than 1 month
  • November 9, 2020

"My doctor had me on another medication, but felt that this would work better for me (I was having success with the other medication). I’ve been on Rybelsus for a little more than two weeks now and I have not experienced any of the side effects. However, I have been eating everything in sight and have gained weight. I’m feeling hungry and snacking more. My previous medication suppressed my appetite and I felt full and satisfied after eating. I think my medication was changed because it was new, and the doctor could make a few extra bucks prescribing it."

2 / 10
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  • Her...
  • Taken for 1 to 6 months
  • January 30, 2021

"Was on 3 mg Rybelsus for a month. Nauseous all the time. After a month, went on to 7 mg for a month. Nauseous all the time. After a month, moved on to 14 mg. Nauseous all the time... This drug is awful."

3 / 10
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  • ric...
  • Taken for 1 to 6 months
  • December 28, 2021

"I've been on Rybelsus for a little over a month for PCOS and have had an overall positive experience - just started the 7 mg dose. My doctor recommended it since I am at risk for type 2 diabetes (>30 BMI, borderline high fasting glucose with a normal A1C, and signs of insulin resistance from PCOS). I get some pretty extreme nausea whenever I eat junk food (fatty and/or sugary), but otherwise feel good. I'm hoping that the nausea I do get helps instill better long-term eating habits. I've also experienced appetite suppression, which has helped me prioritize proteins and vegetables. I did get alternating bouts of constipation and diarrhea when starting this medicine and am expecting that I'll experience the same with the dose increase. I have felt far more energy, and my cravings for junk food have drastically reduced. So far, I've lost slightly more than 10 lbs and am shooting for another 50 to help get my PCOS under control."

10 / 10
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  • Mik...
  • Taken for 1 to 6 months
  • June 9, 2024

"Short story is this drug worked for me! 242 lbs Started 7.4 A1C. 3mg Rybelsus. I was really trying hard. Fast food I cut and was exercising 3 days a week. I have a sweet tooth and my wife is a great baker. She had something ready for me all the time. Sunday doughnut trips. Dairy Queen etc. Cut but not cut all out. 30 days later I did lose some weight. A1C 7.0. The Doc told me the prescribing was 3mg for 30 days then 7mg. I did exercise 4 days a week and cut the sweets some more (that was hard lol). Then the magic happened. In 150 days from start 3mg to 7mg, my A1C 5.1, 195 pounds. 5 more to go. I'm 6 ft tall. I was a fat boy at 242. Now all my old clothes fit with a belt. I know this drug won't work for everyone. However, it worked for me. It will work for you if you try hard. Don't just take the drug. I do get an upset stomach from time to time but worth it!"

10 / 10
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  • Mik...
  • July 10, 2021

"Well, I am on month 2 of Rybelsus and on the 2nd week of 7 mg. I posted my experience last month as well. I am 20 lbs overweight and pre-diabetic for many years. Diabetes runs in my family. I am 60 years old, active, and healthy otherwise. Unfortunately, I do not experience much of anything toward my goal of weight loss. I am slightly nauseous at times. I am constipated. I am not on any other diabetic medication. I weigh 1 lb less, but this could be attributed to a margin of error. I am planning to continue using this medication and see what happens once I am on 14 mg. Considering all the potential serious side effects (thyroid cancer, pancreatitis, and more), this needs to give anyone better results. I believe that people respond differently to everything, so great for those who do well on Rybelsus. See you next time with better news. Stay safe."

3 / 10
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  • Dud...
  • Taken for 1 to 2 years
  • November 8, 2024

"Lost too much weight, lost my appetite for food and life, until my diabetic nurse told me to stop the tablet at once. I had to go to A&E with a UTI, but while there they told me to see my GP and get a two-week referral. I looked so ill they thought it was cancer. Thankfully, it was not cancer. I’ve been off Rybelsus for three weeks and I am eating normally and feel much better. I believe in all honesty it would have been a close thing between me and death."

10 / 10
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  • Rox...
  • Taken for 1 to 6 months
  • May 16, 2024

"User, I followed the prescribed regimen of 3mg daily for two months, taking the pill with minimal water between 5 and 8 AM. However, I experienced persistent nausea, burping with a peculiar taste, and a sharp decline in appetite, particularly for sweets. I lost around 10-12 lbs and struggled to drink water, feeling as if my throat was constricted at times. This led to dehydration and widespread body cramps. Trying Gatorade alleviated the issue temporarily, but the discomfort persisted. Upgrading to 7mg exacerbated the symptoms, causing extreme fatigue, body aches, and lightheadedness. I stopped three pills short of completing the 30-day dose to restore my well-being. In total, I've shed 19 lbs."

7 / 10
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  • Kan...
  • Taken for less than 1 month
  • October 3, 2021

"My blood sugar was always in the 200-300s. Now it’s been at 130. Very good. I don’t eat as much anymore. Don’t crave any junk food like I used to before. I am losing weight. I’m shocked, first thing that has ever helped me. The downfall for me is I can’t use the restroom. I already have issues with that, and it’s gotten way worse. Also, I wanted to know, has it made anyone else’s sex drive go downhill? I used to be all into it, and now I’m like ehh. It’s pretty sad."

7 / 10
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  • caz...
  • Taken for less than 1 month
  • April 5, 2023

"I have been on the 3 mg dose and felt a bit nauseous and had a sore stomach, but it was manageable. Now going on to the 7 mg, but I am on a low GI diet as well, and this combination has helped bring my blood sugar levels down. I have problems with food addiction, and the drug helps curb the cravings by lowering my appetite. So far, I only have positive feedback about Rybelsus."

10 / 10
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  • DLy...
  • Taken for less than 1 month
  • April 7, 2022

"Have been taking the low dosage for 2 weeks now. I have no appetite and have dropped about 7 lbs during that time. The problem is constant GI pain. No nausea, just never-ending constipation and gut pain. I am taking myself off this until I can find an alternative. The weight loss is nice, but the pain just isn’t worth it."

5 / 10
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  • Den...
  • Taken for less than 1 month
  • December 4, 2021

"Had to stop taking 7 mg after 10 days. I tried to stick it out as I had hoped my body would adapt. I first started on 3 mg and was able to tolerate, no problem. When I started on 7 mg I noticed my appetite was gone right away. I'm overweight (maybe 30 pounds), so I was happy about that. I was also nauseous and dizzy. I even threw up with blood one morning. I've only been able to eat crackers and very bland things. After 10 days, I gave up. Now I've been off the 7 mg for 4 days and am still so nauseous and weak. I can't wait for this feeling to be gone. Hoping there is no permanent damage to anything in my body. So sad that I didn't have the great experiences so many people have written about."

1 / 10
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  • Ano...
  • Taken for less than 1 month
  • July 21, 2025

"I had been putting off taking this drug despite my doctor's suggestion because of the possible side effects and, more importantly, the cost. I finally decided to give it a try starting a week and a half ago. I haven't experienced any of the side effects mentioned in the warnings except for constipation the first three days. After that, I started having the opposite effect, meaning diarrhea. I must admit that my appetite has been curbed quite a bit. A protein shake in the morning fills me until mid-afternoon. If I do decide to eat lunch, I have no desire for dinner. Even if I skip lunch, my dinner hunger results in my eating maybe 2/3 of my usual portions, and I have zero interest in dessert later."

8 / 10
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  • Ann...
  • Taken for 1 to 6 months
  • March 7, 2023

"Took 3.5 mg for one month, increased to 7 mg for 2 nights before getting nauseous and experiencing drastic muscle weakness. Hopefully, the muscle weakness will improve soon - I can barely open a water bottle today. It was successful for weight loss in that time. I'd rather open my own water bottle though."

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  • BWo...
  • Taken for 2 to 5 years
  • March 24, 2024

"I've been taking Rybelsus for a few years now. I started off with the 7 mg (after the initial 3mg dose the first month) and used in tandem with metformin. My doctor has recently moved me up to the 14 mg tablets and stopped the metformin altogether. I have done well with Rybelsus (my A1C has been under 6 for the most part) and have tolerated it well. It took me that first month on the 3 mg for my body to get used to this med and I almost stopped due to the nausea and stomach up I had, but I powered through and by the time I started my second month using the 7 mg, the stomach issues had disappeared. My only complaint has been the constipation I've suffered from after taking this drug for so long. I simply take stool softeners every night to deal with the problem. All in all, I am happy with Rybelsus and it has worked wonders for me in keeping my blood sugar/A1C low."

10 / 10
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  • NDH...
  • Taken for less than 1 month
  • April 30, 2022

"It is 11 pm right now, and I should be sleeping, so I can go to work in the morning. Instead, I am here, trying to see if anyone else has anxiety and the feeling of a lump in their throat. Today is my second day taking Rybelsus (3 mg) for weight management. I had 2 anxiety attacks yesterday and 4 today. The feeling of a lump in my throat makes me go down a rabbit hole and consequently, I have anxiety/panic attacks. Will this feeling of having a lump in my throat go away? Further, will the anxiety/panic attacks abate? I truly hope these things go away. I don't know if I can recommend this medication at this point."

1 / 10
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  • Qui...
  • Taken for less than 1 month
  • January 30, 2021

"I have been taking 3 mg for almost a month now and not really any symptoms. I think I got nauseous one time, and that was it. I also take a vitamin D twice a week with it and have been fine. I was given the medication due to having high insulin and weight loss and will start 7 mg next week. Can’t wait to see how that goes."

10 / 10
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  • AK0...
  • Taken for 1 to 6 months
  • July 14, 2025

"I have been diabetic for the past 15+ years. My A1C for the past year has been around 8-9, and my doctor put me on Rybelsus 3 mg to try along with 1500 mg Metformin (which I was already taking). The initial few days were horrible. Had constipation, bloating, and vertigo problems. I had to change my eating habits and maintain discipline of eating only 3 times. Every time I have anything between meals, my nausea returns. I also do brisk walking for 30 mins, 3-4 hours after lunch. I am also using Freestyle Libre 3 to monitor my sugar all the time. Walking helps maintain my sugar levels in range. After 4 months, my A1C came down to 7.8. My doctor has increased the dosage to 7 mg. With 7 mg, my sugar levels seem to be much better than with 3 mg. Waiting on my next visit with the doctor to check my A1C and hoping to be below 7 (target set by doctor). Will update this post after my next visit and share results."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.