Ozempic and Vomiting: What Users Say

• Sti...
• Taken for less than 1 month
• July 21, 2021

For Type 2 Diabetes "I did one injection and have been ill since. I have had acid reflux, burping, vomiting, constipation, headache, and dizziness. I tried to eat small meals and drink plenty of water as directed by my physician, but I have been unable to hold anything down. Five days after my first injection, I'm off work, drinking Pedialyte, trying to get my strength back, and avoid being hospitalized. This is the worst that I have ever felt in my life."

• Tuu...
• Taken for 6 months to 1 year
• July 23, 2021

For Type 2 Diabetes "I started with 0.25 Ozempic in November 2020 and upped my dosage to 0.5 in January 2021. My A1C is the same as when I was taking 2000 mg Metformin daily (5.1-5.3%). My doctor decided to switch me to help with weight loss and manage my pre-diabetes. I have lost 47 lbs, which is great, but it isn't a healthy way to lose weight. I met with a GI specialist and was diagnosed with gastroparesis, they had me discontinue Ozempic to see if my symptoms would disappear. That was 6 weeks ago, and my stomach is still paralyzed. I have sulfur burps, diarrhea, severe constipation, and vomiting daily. I now have to eat a low FODMAP diet and can only manage a few mouthfuls of food at a time. I have no quality of life anymore, I can no longer enjoy many of the things I used to, which has caused me severe anxiety and depression. While the weight loss benefits sound appealing, please think twice before taking this drug."

• Shy...
• Taken for 1 to 6 months
• March 26, 2022

For Cardiovascular Risk Reduction "I always had some side effects of Ozempic. Mainly exhaustion, nauseous, occasional throwing up after eating, constipation. As month 3 came and the dose increased to 1 mg, I ended up in the emergency room. I was vomiting and had liquid diarrhea for 4 days. My heart rate was elevated, and my potassium was dangerously low. At the time, I thought it was a stomach bug-until the next injection caused the same effects. I've been on anti-nausea medication since. I can see why it takes the appetite away-being exhausted and nauseous 24/7 is terrible. Potassium is still not where it should be. Hoping this gets out of my system fast."

• Cau...
• March 3, 2022

For Type 2 Diabetes "I took .25 for about 6 months and thought this was a miracle drug. Caused slight constipation, but I dealt with it. When they increased me to .5 mg, I started violently vomiting the next day. No one could figure out what was wrong with me. Pancreatic enzymes were high, but not high enough to diagnose pancreatitis. I could barely eat for two months. Gas, bloating, side pain, back pain, stomatitis pain, non-stop burping, constipation, nausea, vomiting off and on. My food perpetually felt like it was backed up into my mouth. They had to take me off of the drug, and now my sugars are higher than ever, and no one can help me. They were okay before, but now doctors consider me as failing two types of drug classes because of this, won't give me my old meds back, and I may have to go on insulin. I am gaining weight like never before and am so tired that I can barely function. They now believe it gave me gastroparesis, and I can't get better. I would recommend this medicine to no one."

• 9ru...
• Taken for 1 to 6 months
• September 10, 2022

For Cardiovascular Risk Reduction "Absolutely horrific. I get it works for most people, but unfortunately not me (and should not be promoted as a miracle drug that can help all obese people lose weight, as it doesn't work for everyone). I took 0.25 (the smallest dose) for 3 weeks and nothing (I yo-yoed with my weight; lost a bit then gained it again). After 3 weeks (not sure why 3 weeks for me), the main side effects kicked in. Diarrhea/loose stools, constipation, vomiting, nausea. Worst side effect was for 3 nights in a row, at about 3 a.m. I projectile vomited. First night I almost aspirated and choked on my own vomit trying to make it to the toilet without throwing up. Second night, even though I had the bathroom bin next to my bed, I was still projectile vomiting, and I couldn't sleep as I had a panic attack that I'd pass away overnight and my family would find me dead as I couldn't breathe as I had undigested food stuck in my esophagus. Gave up after 5 weeks of the lowest dose."

• Bis...
• April 7, 2023

For Weight Loss (Obesity/Overweight) "I am going on week 11 with Ozempic, and have lost 24 pounds. I have had all 5 of the main side effects, nausea, stomach pain, vomiting, diarrhea, and constipation. I am happy with the weight loss, so am learning to manage these. By trial and error, I've found that I can't eat much at one time (don't really want to), need to avoid fatty foods, drink lots of fluids, and take Senna laxative every night for the constipation, and keep Zofran around to help with nausea. Yes, these first few weeks have been difficult, but the weight loss is worth it to me. Plus, the side effects get less the longer I'm on Ozempic. I am currently on 1.0 mg and think that's quite enough. I am rarely hungry and often have to make myself eat. I hope to lose 65 pounds total."

• Dro...
• Taken for 6 months to 1 year
• April 2, 2025

For Type 2 Diabetes "I've lost about 40 lbs since starting Ozempic 11 months ago. My A1C is now within normal limits, but I still take Metformin. My non-alcohol fatty liver disease has resolved as well. I experienced nausea and vomiting early on in treatment, but that has mostly resolved. I feel hunger less and feel full longer. Constipation is a big problem, so I use an occasional stool softener or eat some prunes to keep things moving. The medication decreases the pleasure I get from food, which is weird sometimes. When I go out of town, I used to look forward to trying a new restaurant, but now it's just 'meh' no matter what I eat. I found that I have more nausea if I inject in the abdomen, so I do it in my arm or thigh instead."

• Dee...
• Taken for 1 to 6 months
• June 2, 2019

For Type 2 Diabetes "I am so grateful for this site. I thought I was alone in experiencing these awful side effects. Yesterday was the worst. Started with horrible rotten egg burping. Woke up with vomiting. I started on 0.5 and decreased to 0.25 because I was experiencing nausea all the time. I am tired. Two weeks ago, I had severe constipation. It really helps with glucose control. I have been on it for four weeks. I plan to see my MD this week. I don't think I can continue. I've only lost 1 lb so far."

• Don...
• Taken for 1 to 6 months
• August 23, 2021

For Type 2 Diabetes "Been on Ozempic 3 months. I hate this mess. I’m constantly throwing up (not good, just bile). I’ve never been so weak in my life. Since taking the drug, I constantly pass out even though I’ve had to decrease my long-term insulin. I’ve consulted with my doctors, and they keep saying let my body become accustomed to the med. The erratic bowel issues are insane. One day I’m so bloated from constipation, 2 days later I have diarrhea. Not much I can eat without throwing up. I honestly don’t know how much longer I can do this."

• Ann...
• Taken for 1 to 6 months
• July 18, 2021

For Type 2 Diabetes "I started this drug to try and lower my A1C, which had climbed to 7.2. My nurse practitioner put me on it. She showed me how to do the injections, but no warnings of side effects. I took a .25 dose for 4 weeks, suffering pain in my stomach that radiated to my back. Absolutely no craving to eat anything at all. Had constipation. Then I went to a .5 injection and was fine for a bit until severe nausea began, along with dizziness and vomiting. I thought it was going to be the end of me, because then the unrelenting diarrhea began. I waited days in bed, so very ill, and decided to quit this awful medication. I have lost 6 pounds, and my morning glucose numbers are 107, it's lower, but feeling this deathly ill just isn't worth it. I quit the medication, though I understand it could take 5 weeks to leave my body. Beware of this drug."

• 0ct...
• May 24, 2021

For Type 2 Diabetes "I was placed on Ozempic last year because Metformin has always caused awful nausea. I have never in my life had any issue with constipation until I started taking this medication. I was so sick with diarrhea and throwing up 3 weeks ago I thought I'd actually die. I have had bad rashes. I think they would have been worse if I were not on allergy medication. The latest rash is healing. I've never had to take laxatives until this medication. I'd rather deal with the nausea than rashes, vomiting, constipation, poor appetite, and legs feeling strange. I wasn't overweight, so that was not an issue. My numbers have never been more than 6.1. Then, when I read that it can cause death, that was the end all for me. It may help someone, but I'm not the someone! Medicine should make one better, not worse. When I first started this drug, I spoke with someone from the company that makes it about the constipation issue and also my doctor. They said that it would get better, but that hasn't happened."

• Anonymous
• Taken for 1 to 6 months
• May 23, 2023

For Type 2 Diabetes "Twelve hours after I was injected with 1 mg Ozempic, I had severe headaches and vomited for almost four days. No matter what I eat, I feel dizzy and have a bad taste in my mouth. I ate soft and nonfat foods, but still, the vomiting continued. I never had constipation or diarrhea."

• Ann...
• Taken for 1 to 6 months
• October 22, 2021

For Type 2 Diabetes "This is a horrible drug. I thought I was dying, my stomach hurt so bad. I'd be in a ball on the couch. I had headaches, constipation, vomiting, could not eat, lost 20 lbs so fast, my skin sagged. Do not take this medication."

• Mia...
• Taken for 1 to 6 months
• April 10, 2023

For Type 2 Diabetes "Be careful with this drug. In my opinion, all Ozempic does is cause disordered eating habits and make you sick to the point of vomiting if you do try to eat a decent meal. This is not sustainable for long-term health. Also learned the hard way that in some, it can cause reactive hypoglycemia, which can be very dangerous. I did lose about 10 pounds in the 6 weeks I was on it, which yes, is nice, but I wouldn’t say it was “easy” because I was suffering the whole time with constipation, vomiting, migraines, etc. It HAS motivated me to work as hard as I can to maintain my health and weight as much as I can without these powerful drugs, though I will say that."

• not...
• Taken for 1 to 6 months
• May 3, 2023

For Type 2 Diabetes "I unfortunately had a very severe reaction to Ozempic. I usually do suffer side effects from most medications, but thought I would give it a try. The first two weeks were headache, general stomach ache, and constipation lasting 2 days after each injection. Weeks 3 and 4 got worse. Stronger reactions, lasting longer. Week 5, I started the double dose, and I was pretty ill for 2 days. Week 6 and 7 was rough, but I thought I could ride it out. Week 8 had me in emergency twice for diarrhea, vomiting, headache, and major dehydration. I was unable to eat or drink anything. I had to get rehydrated and be given anti-nausea meds on both occasions. I guess my body slowed the release of food so much I had a massive buildup to the point even a sip of water made me extremely nauseous. Ozempic is not for me."

• Cha...
• Taken for 1 to 6 months
• March 25, 2021

For Type 2 Diabetes "Please stop taking Ozempic. I have been taking it for 12 weeks, started with 0.25 for the first 4 weeks, then moved on to 0.50. First 4 weeks, minor side effect, but my pulse rate started to go up resting from 65 to nearly 80. Once I started the 0.50 dose, I started to lose weight, lost 1 stone in 8 weeks, but suffered so much: vomiting, constipation, stomach pain, dehydration, depletion of magnesium in body, and resting heart rate to 94. Was hospitalized last week and was on a drip for 2 days. I have decided to stop taking it, my next injection is due in 2 days. I am hoping stopping does not cause other issues, I will revert to taking insulin. So please do not start this drug. There are other options to manage your diabetes."

• Rih...
• Taken for 1 to 6 months
• May 20, 2024

For Type 2 Diabetes "I have type 2 diabetes and I am obese. I started this medication in November 2023. I stopped using it for three months due to a shortage in the market in my country. I used 0.25mg for the first month, 0.5mg for the next three months, and 1mg for two months. The last dose of 1mg was taken on May 17, 2024. In November, I weighed 91kg, and I have reached 75kg or perhaps even less now. For my health, I feel significantly better while working or going upstairs. Regarding side effects, I experienced tiredness, vomiting, headaches, nausea, constipation, and stomach pain."

• RAM...
• Taken for 1 to 6 months
• May 28, 2025

For Type 2 Diabetes "I've been taking Ozempic since the beginning of March 2025. My starting dose was 0.25 and I am now at 1.0. At the time I started, I weighed about 193 and am now weighing 156 lbs. The only side effects I seem to be dealing with and do not like are nausea, vomiting, and constipation. Ozempic has curbed my appetite considerably, as well as my liquid intake, which I don't mind since I've lost a lot of my weight. Right now, my biggest problem is finding clothes to fit me and deciding if I should keep my old clothes or donate them. I really haven't bought much in the way of new clothes in part because I don't know how much more weight I am going to lose, plus the expense of buying new clothes. My goal is to weigh somewhere between 135 and 140. My A1c is down from 8.9 to 8.1, I would like that to be lower, like 7.1."

• Anonymous
• Taken for 1 to 6 months
• January 7, 2025

For Type 2 Diabetes "I have been on Ozempic now for 14 weeks. My readings were very high, could be between 12 and 20, but since I’ve been on Ozempic my readings are down to 6.2, sometimes lower. I feel so much better, and my blood tests are good about my other health conditions. But I have hives, and it’s itchy and driving me nuts. And I have vomited on and off and had terrible stomach pains at first. After a few weeks, that eased off. I can’t eat much, so that worries me, but I’ve lost 12 pounds, so I’m happy about that. I don’t enjoy food anymore, and I have decided to have small meals during the day. Constipation was a problem, but I take a Metamucil fiber tablet each day and now have no problem."

• joh...
• Taken for 1 to 6 months
• June 16, 2025

For Type 2 Diabetes "Reduced blood sugar from 10 to 7.1. Killed my hunger completely, no more food cravings. Side effects became disabling, had to discontinue using. Became bloated, nausea was bad, 1st time I have vomited in 50 years, fatigue, constipation, going to the emergency room as no doctors available to help."

• Pat...
• Taken for 1 to 6 months
• July 27, 2021

For Type 2 Diabetes "Began on 0.25 in May 2021. At first, zero side effects, no appetite at all and glucose plummeting. Went up to 0.50 in July. After 3 weeks, I had 2 days of severe stomach pain, vomiting (which I never do), and weakness. Was supposed to take an injection that day, but I did not. The next day, went back to 0.25 and so far so good. Outside of mild constipation (I don't eat much), I have to say the drug is a great one. I may change my mind if I start feeling pain every week, but so far so good. I see my MD next month and will ask him if I should go back up to 0.50."

• Sue...
• Taken for less than 1 month
• June 1, 2023

For Weight Loss (Obesity/Overweight) "I need help to decide if Ozempic is good for me. The side effects scare me: nausea, vomiting, constipation, and exhaustion. Yikes! I really need the weight loss, though. I really want to try it. I'm curious if insurance will cover it."

• Bet...
• Taken for 1 to 6 months
• July 5, 2021

For Type 2 Diabetes "If you like constipation, being nauseous, stomach pain, burping, pain from stomach acid, loss of appetite, and vomiting, this drug is for you."

• Anonymous
• Taken for 1 to 6 months
• August 25, 2021

For Cardiovascular Risk Reduction "I have lost 20 lbs, but have severe nausea/vomiting and constipation. Zofran and laxatives do help, but I was wondering if anyone could tell me what kind of diet would be most helpful for me."

• Ros...
• Taken for 1 to 2 years
• December 6, 2024

For Type 2 Diabetes "I’m losing weight, but I have nausea sometimes. I vomit, constipation, loss of appetite, 1 unit."