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Ozempic and Nausea: What Users Say

Reviews for Ozempic

Commonly mentioned side effects
  • Mic...
  • Taken for 1 to 6 months
  • June 7, 2023

For Weight Loss (Obesity/Overweight) "I had a horrible experience. Abdominal pain going to the back. Constant nausea. Depression - very strange feeling, almost like an out-of-body experience. For the first time, I found myself HATING my body. Extreme tiredness. Difficulty focusing. Gained 9 pounds in 3 weeks. Constant headaches."

1 / 10
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  • Big...
  • Taken for less than 1 month
  • August 16, 2022

For Type 2 Diabetes "Ended up in the emergency room on the day of the second dose. Triggered a gallbladder issue and ended up elevating my liver enzymes. Symptoms mimicked a heart attack or pancreatitis. Hard to tell the difference. Severe abdominal pain radiating to the back, elevated heart rate, nausea, gas, bloating. For some people, this type of medication is very, very bad medicine and totally not worth it. I lost 10 pounds in two weeks because it made me so sick I could not eat or drink. One day this will also have an FDA black box label on it like Byetta. A class action lawsuit will be on your TV commercials. I would be seriously careful if you plan on taking this medication for anything, weight loss or glucose control. Not worth it. Once you get sick, you will be longing to get the stuff out of your system and will be physiologically impacted by the experience. No antidote. Have to wait it out. Never again. The Russian roulette of diabetes medication. Taker beware."

1 / 10
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  • Wen...
  • Taken for 1 to 6 months
  • November 30, 2018

For Type 2 Diabetes "Hospitalized twice with severe abdominal pain and nausea, diarrhea, and vomiting. Second visit had a gastric emptying study done. Normal gastric emptying is 30 min, mine was 800 min. Basically, this med damaged the vagus nerve and paralyzed my stomach, not allowing food to empty. Severe symptoms. Missed work, hospitalized a total of over 2 weeks. Praying my stomach returns to normal. Diagnosed with gastroparesis caused by Ozempic."

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Frequently asked questions

  • DAn...
  • May 12, 2021

For Cardiovascular Risk Reduction "Within 12 hours of the first dose, vomiting occurred and continued for 3 days. Unable to keep any food down; small sips of ginger ale the only thing I did not vomit. Lower abdominal tight cramping. Pain in the upper abdomen. Vomiting at all times of day and night, which added to the fatigued feeling. Days 4-7 felt queasy. Second injection: same side effects as first. Emetrol helped me eat dry toast (1/2 slice) and weak tea. Third dose: same effects, but only for 2-1/2 days."

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  • mac...
  • Taken for less than 1 month
  • October 21, 2018

For Type 2 Diabetes "After the first 0.25 mg injection, I was extremely bloated and burping within 5 hours. I woke the 2nd day with extreme bloat, diarrhea, nausea, and abdominal pain. I could not eat or drink a thing because of severe bloating. This lasted 5 days. Foolishly, I did a 2nd dose the next week of 0.25 mg. This time, I became much, much sicker with the same symptoms but more severe. Abdominal pain severe, bloating was so bad I had to go to the ER, my stomach was as tight as a drum. They were talking about sticking a tube in my stomach to release the incredible pressure, instead, I came home and rolled around in agony for 3 days. I stopped using it, but the side effects continued. 7 weeks of severe gastroenteritis that caused so much inflammation in my body, I have been in so much pain. No amount of weight loss is worth this level of suffering. If you have any GI issues like gastroparesis, you really should not be risking it with this drug, it says so right in the insert."

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  • Sas...
  • Taken for 1 to 6 months
  • June 26, 2019

For Type 2 Diabetes "Been on this for 5 weeks now. Levels are finally starting to stabilize, and I feel more like a human. The nausea has been horrendous, the weight is falling off, 10 lbs so far. Can't overeat or the nausea gets worse, and I throw up. Abdominal cramps were bad week 2 & 3 but are less frequent and not bad too often. Constipation has been hard for sure, I have to take something to help me go. Just increased from .25 to .50 five days ago, and the nausea is hitting me more frequently again. Tums, a fan on near my face, and nausea suckers are so helpful. The side effects can be pretty severe, but I gotta keep trying to push past it. Good luck if you take this."

9 / 10
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  • M1a...
  • Taken for less than 1 month
  • June 16, 2019

For Type 2 Diabetes "Started on 0.05 dose of Ozempic 3 weeks ago. Side effects are horrible! Only took 2 times and had to stop, have had diarrhea and abdominal pain ever since. Definitely takes away your hunger. I am a chef and love food, but am too nauseous to enjoy eating! It might work for some people, but I would not recommend it. Side effects are not worth it!"

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More FAQ

  • Gpo...
  • Taken for less than 1 month
  • February 11, 2019

For Type 2 Diabetes "Don’t try it!!!! Should be taken off the market. I lost 6 pounds in a week, but the nausea and abdominal cramping along with severe constipation aren’t worth it. I wish I wouldn’t have ever tried it. I was supposed to take my 2nd dosage on Saturday, but I didn’t-still feeling sick after I eat. I hope I get better soon. Worst decision ever. Once again, don’t try it!!!"

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  • Ree...
  • June 30, 2019

For Type 2 Diabetes "The first week I took Ozempic, I had nausea and watery diarrhea for about 12 hours. Indigestion with a sulfur taste for 1 day. The second week, the nausea, diarrhea, and indigestion lasted for 2 days. The third week, it lasted for 6 days. Severe abdominal pain, I could barely get out of bed. I had to stop taking this medicine. The only good thing was I lost 12 pounds in 2 days."

4 / 10
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  • OCo...
  • Taken for 1 to 6 months
  • May 29, 2023

For Type 2 Diabetes "I started Ozempic at the end of March 2023 for overall better A1C control, weight loss, and reduction in cardiovascular risk. Started at 0.25 mg for the first week and increased to 0.5 mg since. For the first month, I had strong nausea, lightheadedness, and significant constipation with abdominal discomfort. I also felt very tired all day, which I found was due to not eating enough carbs daily, as Ozempic tends to significantly reduce the appetite. I stuck with it, and after one month at 0.5 mg, the only remaining issue is constipation, which I try to manage through over-the-counter laxatives and prescription medication once a day. Over two months, I lost 25 pounds (235 lbs down to 210 lbs)! My daily fasting blood sugar results are down 20-25 points from before starting Ozempic (A1C to be tested in one more month) and managing my energy level by ensuring enough carb and protein intake. So far, so good!"

9 / 10
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  • die...
  • Taken for less than 1 month
  • March 8, 2023

For Type 2 Diabetes "After being on Ozempic for 3 weeks, I do not believe it is the right medication for me. I have a history of slow digestion issues, which I did not fully realize before I started taking Ozempic. The medication made that worse. I am experiencing constant mild to moderate nausea, sometimes accompanied by excessive gas and abdominal pain. I believe I am at a point where this will be the norm if I continue to take it. I have noticed my blood sugar going down, but I have been able to control it through diet and a bit of exercise in the past. So I am unsure if it is because I can't eat as much because of Ozempic or whether I'm just eating smarter. I am going to stop taking it and try to take what I've learned about eating habits and apply them without Ozempic."

2 / 10
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  • Fro...
  • Taken for less than 1 month
  • December 13, 2021

For Type 2 Diabetes "My doctor prescribed it as a miracle drug, bought a 0.25 mg kit. My doctor gave me instructions, but I found better instructions on YouTube, so the next day I was ready with all that info. I cooked a light soup, no carbs, no fat, etc. I drank water, washed my hands, cleaned my belly, and did the shot. All was okay. After a few hours, abdominal pain, my eyes started to itch, then blurry vision. I went crazy, wondering what happened to me, went to bed, then the nausea came with a headache. The next days I was sick and did not go away, so I phoned my doctor. She said it's all in my mind and I will get used to it. Now I am afraid of the second injection, is it worth it? Why pay for an expensive drug to get sick? The only positive was that it lowered my morning blood sugar from 100-110 to 88. I take 1000 mg of metformin twice a day. For others, do not use it for the first time and go to work, it's good to do it when you do not have work the next day."

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  • Juw...
  • Taken for 6 months to 1 year
  • November 19, 2022

For Type 2 Diabetes "I started on 0.25 for four weeks, had nausea, dizziness, burping nonstop every day, off-the-wall gas, and bloating. Went on 0.5, more or less the same side effects except more abdominal pain. Then went to 1 mg, my skin started feeling like I had a bad sunburn from the waist up. It hurt when clothes touched it. Four weeks later, went on 2 mg. All same symptoms. Then I started having severe neck pain and shoulder pain. Was on 8 months and only lost 16 pounds. A1c went from 7.5 to 5.5, but a lot had to do with eating less. I have EPI, so it was not worth it to me to take it anymore. Also, thyroid cancer runs in my family. Had a friend tell me her friend got thyroid cancer after 3 months, also had a lot of diarrhea. Now I'm off, no symptoms, skin feels better, and sugar around 130."

3 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • August 30, 2021

For Type 2 Diabetes "Been on it for 9 months, off metformin now and lost 30 lbs. A1C from 9.1 to 5.5. Still have nausea, abdominal pain, weakness, constipation, dyspepsia with the injection. I have these for 2-3 days after the injection. It did its job but not sure I can do it long term."

8 / 10
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  • Ano...
  • Taken for 1 to 2 years
  • May 27, 2025

For Type 2 Diabetes "This drug is helpful in maintaining a good blood glucose level. It has helped in lowering my overall weight, which was not working before by diet. At this time, I am on a 1 mg injection, but I feel I am having reactions of nausea, dizziness, bloating, burping, some abdominal pain, and constipation."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.