Ozempic and Headaches: What Users Say

• Typ...
• Taken for 1 to 6 months
• May 16, 2023

For Type 2 Diabetes "I am on my 3rd month of taking Ozempic. No decrease in A1C as of yet. Weight loss, none. Ease of use, I find handling the needles cumbersome. The needles are smaller than Trulicity and less painful to inject. Less bruising at the injection site. Current side effects: nausea, stomach pain, stomach discomfort, swelling, bloating, increased constipation, increased hunger, sour stomach, headaches. I find I am forced to take additional medication/supplements in attempting to eliminate some of the side effects. I've taken stool softeners and laxatives in order to improve constipation with limited success. I am taking a pain reliever almost daily for headaches. I am also taking medication to help ease the nausea with limited success."

• Dan...
• Taken for 1 to 6 months
• July 4, 2019

For Type 2 Diabetes "Two days after the injection, I get a pretty bad headache, indigestion, and a bloated feeling that lasts the day. This week (6th shot) has been different. It’s the second week the dose was raised from .25 mg to .5 mg. I felt like I had to throw up. The indigestion, burping, constipation, sore muscles, aches, and heavy sweating all felt like I had a horrible flu. I stayed home from work. I went back to work today, when I normally get the headache, and had heavy sweating, burping, indigestion, cold clammy skin, bloating, diarrhea, and depression and anxiety (years since I had either one). Tonight I still have bloating, wrists and shoulders sore, and indigestion with burps. My neck is really stiff. The normal headache has started with a little dizziness. I am still debating what to do as this has been an effective medicine. My blood sugar has gone from 290 to 90 to 140 when I check it. I have lost weight as well."

• Hat...
• Taken for less than 1 month
• July 19, 2022

For Cardiovascular Risk Reduction "This is the worst medication I have ever had. Side effects of egg burps, vomiting, bloating so bad. DO NOT TAKE THIS. 30% of people that try this drug end up having problems with it. DO NOT TAKE. You can't eat, everything that goes into you makes you want to throw up. DON'T TAKE! Never-ending nausea and weakness. DON'T USE, SAVE YOURSELF. Headaches....."

• Dix...
• Taken for less than 1 month
• June 11, 2022

For Cardiovascular Risk Reduction "Two days after my first injection, I had horrible sulfur burps that were making me feel sick. By that evening, I had horrific stomach cramps; by 11:30 pm, I had uncontrollable diarrhea! My prescriber advised me to eat six small meals a day and that the symptoms would improve with each injection. I left it twelve days before my next one (as I had a couple of social things I didn’t want to miss if it happened again) and thought at first it was better. A headache day one, nausea on day two, but sulfur burps again by day three. I got indigestion medicine, but it didn’t even touch it. That night, same again; cramps, diarrhea, more burps, and this time intense nausea too. I decided at that point it might not be for me! I really hope it helps some people lose weight, but don’t expect a quick easy fix! I actually felt fatter the whole time I was on it as I was so bloated and tender."

• Ver...
• Taken for 1 to 6 months
• July 24, 2021

For Type 2 Diabetes "I have been on Ozempic for about 3 months. At first, it was great. I wasn't hungry and felt so much better. Increased to 0.5, and I feel terrible. I've gained 15 lbs, I'm bloated and sick, constipated, exhausted, elevated heart rate, ventricular tachycardia, my period was on point every month, but now it's messed up. I feel full but hungry, and it never stops. Have Dexcom, sugar between 250 and 390 always, but my A1C has dropped from 8.4 to 6.4 (I don't understand that). I hate milk, but since I've been on Ozempic, I crave it and have become addicted to it. I drink a gallon a day. Literally. On the 0.25, I was very hopeful and thought this would be great for me, but it is not. I see my endocrinologist soon to discuss other options. Overall, I'm exhausted, sleeping all the time, elevated heart rate, weight gain, milk addiction, messed up period, constipation, increase in physical pain and depression, headaches for days after injection... just not worth it to lower A1C only 2 points."

• hal...
• Taken for less than 1 month
• June 4, 2023

For Type 2 Diabetes "The major side effects are all I got with this med, which includes upset stomach, heartburn, burping, gas, bloating, nausea, vomiting, stomach pain, loss of appetite, stomach flu symptoms, headache, dizziness, and tiredness."

• Meg...
• Taken for less than 1 month
• March 16, 2021

For Cardiovascular Risk Reduction "I started this medication last week on Tuesday. The first two days, I had a headache and a flu-like feeling. Throughout the week, I felt nausea almost daily, bouts of diarrhea, and bloated. Today is my second dose of 0.25, and I lost 4 pounds in 7 days (probably the fact that anytime I eat, my next bowel movement is diarrhea). I have felt a general unwellness for the last 7 days and am anxious about how this week will go, as I haven't been able to accomplish what I normally am able to. If this week gets worse and I start vomiting and being really unwell, then I will stop taking this medication. I definitely don't have the same appetite I did before, and my junk food craving has basically been vanquished, however. If the symptoms don't peter out or they get worse, I don't see the point, as it affects my son's life as well when I can't be the best mom I can be."

• 2nd...
• Taken for 1 to 6 months
• October 21, 2024

"I lost 20# in 5 months over a year ago and gained it all back in 6 mos. The top side effects then were nausea, constipation, bloating, and big hair loss, strangely starting a month after discontinuation and lasting 5 mos. Much hair grew back. I started up again a week ago and more, this time unbearable side effects. Horrible headaches at the base of my skull, acid reflux that chokes me and burns my throat at night, flashes of light and wisps of wind in my face at night, nightmares, hair coming out in swaths, erratic high BP (I have high BP, but it was under control before O.), bad joint pain (hips especially), extreme urinary incontinence (swelling down there with pee dribbling), and extremely emotional (incessant crying) just 5 minutes after injection. Five minutes after the second shot (second week), all the above that had “slightly” eased up came back full force! Husband again losing weight with doable nausea and blah feeling. *I have a lot of side effects to most meds."

• Vic...
• Taken for less than 1 month
• December 9, 2024

For Type 2 Diabetes "I have been taking .25, and I am suffering nausea, headache, and bloating. I thought it would be better after the first 2 weeks, but it's worse. I think I will have to stop taking it. I have not seen any benefits."

• 65...
• Taken for 1 to 6 months
• March 1, 2025

"I'm on week 5 in a few days. Started at 0.25 cc inj. Mild nausea and headaches. 5' 10'', 186 initial weight. I'm 40 lbs overweight. I tried to eat right and exercise, but the weight was not budging. Just going up, and I'm very active outside. Today I'm down 10 pounds, it's a slow process for me, it seems. Very little appetite, and you can't eat much at one time or you feel terrible, bloated, nauseated, headaches... but I'm determined to drop another 30 lbs. I'm just surprised at how little I eat for a portion and am completely full... and still the weight clings on. I could not do it without this drug."