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Ozempic and Fatigue: What Users Say (Page 3)

Reviews for Ozempic

Commonly mentioned side effects
  • Joe...
  • Taken for 1 to 6 months
  • October 17, 2024

For Type 2 Diabetes "Terrible side effects: lower stomach pain, sleeping too much, and fatigue. I've only been taking for two months at 0.25 mg and 0.5 mg each month. I hope for better results when I increase to 1 mg next week..."

5 / 10
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  • NEW...
  • Taken for 1 to 6 months
  • March 7, 2025

For Type 2 Diabetes "I started out on 0.25 once a week and then 0.5 for two more weeks. I am now at 1.0. I experienced a little nausea in the beginning, but it has subsided. I find it interesting that I don't crave salty foods and actually turn them down. I am craving salads, which I find interesting. I've lost 7 pounds in 5 weeks, and now with the increase, about a pound every two days. The best part is I am on Metformin and Janumet, with a daily blood sugar averaging 340. With the addition of Ozempic, my average blood sugar has been at 122. My A1C has dropped from 11 to 9, all in a very short time. I suffered heart failure last year, and my refraction rate is now back to normal at 55 percent. I am now experiencing some fatigue, but that could just be my body adjusting to all the meds on board. I feel I now have a brighter future ahead, especially with the normal sugar level, and am planning to do a lot of outdoor activities this summer. I've also gone back to water aerobics and have my life back."

10 / 10
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  • Ric...
  • Taken for 1 to 6 months
  • June 25, 2025

For Weight Loss (Obesity/Overweight) "So far, so good. Six weeks on. Constipation's been an issue. Definitely has cut my appetite down, and I lost my taste for my weekend beer and have a glass of wine or two. Everything else has been fun. Little fatigue I’ve noticed, but hopefully I continue to lose weight."

8 / 10
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Frequently asked questions

  • Not...
  • Taken for 1 to 6 months
  • October 3, 2024

For Type 2 Diabetes "Still early, so this may change as time goes on. I am currently taking 0.5, increasing after the next dose. In the beginning, I had stomach pain and sickness, but these symptoms died down after I learned to eat more protein and not to skip meals. Another thing that bothered me at first was fatigue. I could not keep my eyes open. I slept a lot, and if I had something to do that day, it took everything in me just to make it through the day. These symptoms also subsided after I stopped skipping meals. I would be lying if I told you my choice to start taking Ozempic wasn't to help me lose weight. That was one of the major selling factors for me. Anyone who knows anything about diabetes knows you do pack on the weight, and any help shedding those unnecessary pounds is a plus. I can't say I have lost a lot of weight yet, but with what little time I have been on Ozempic, I can see a decent decrease in my weight. As for my diabetes, my A1C will tell in time."

8 / 10
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  • Cor...
  • Taken for 1 to 6 months
  • July 29, 2022

For Cardiovascular Risk Reduction "I used this medicine for 3 months to help me lose an excess weight of 30 lbs. I lost 10 lbs. Initially, I had a few side effects: nausea and indigestion. But by the third month, I felt really sick. I asked for blood tests because I was so exhausted. My blood tests were perfect. The indigestion and heartaches got worse. Eventually, it became unbearable. I'm burnt out, so it just made my condition worse. Zombie. For people who support it well, it's great. But if you have a digestive sensitivity, it's at your own risk. I last used the medicine 10 days ago, and I still have digestive problems and heartaches, as well as fatigue. But the fatigue was present before the use of this drug. I lost 10 pounds out of 30 pounds in a month and a half. Then I didn't lose any more, and I continue to be careful. The drug works for 7 days, so it's been 10 days. It is completely eliminated from our body after 5 weeks. It is especially the fatigue that causes me problems. But it's normal when you're still in indigestion."

3 / 10
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  • joh...
  • Taken for 1 to 6 months
  • June 16, 2025

For Type 2 Diabetes "Reduced blood sugar from 10 to 7.1. Killed my hunger completely, no more food cravings. Side effects became disabling, had to discontinue using. Became bloated, nausea was bad, 1st time I have vomited in 50 years, fatigue, constipation, going to the emergency room as no doctors available to help."

4 / 10
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  • Ris...
  • Taken for 1 to 6 months
  • May 15, 2025

For Weight Loss (Obesity/Overweight) "I have been on Ozempic for about 3 months. Started at 0.25, then went to 0.5, then went to 1.00 2 weeks ago. Had some minor side effects (a little stomach upset, fatigue) with the lower doses, but just this past week, I have started severe diarrhea. I literally can't keep anything in my system. It is working okay... I have lost almost 15 pounds, but I am going to adjust the dosage down if the diarrhea doesn't stop. I also have had a huge increase in burping, which is manageable. Overall, I have positive things to say about this medication, but I think that dosing is pretty specific to the person and should be discussed with your primary doctor if severe side effects continue."

7 / 10
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More FAQ

  • Che...
  • Taken for 1 to 6 months
  • August 24, 2024

For Type 2 Diabetes "Have been on Ozempic for about 2-3 months at 0.25. Experienced/experiencing: nausea, heartburn, fatigue, light-headedness, constipation. Nausea has calmed down but still occurs. Heartburn has developed over the last month and is definitely not subsiding. Seems I am always tired. Sometimes getting up, I become light-headed and off balance. Constipation is quite prevalent even with eating high fiber fruit and vegetables, and I am doing my best to drink plenty of water, starting with hot lemon water and honey every morning. I do not know if I would recommend this drug or not. Everyone is different. Thank you."

5 / 10
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  • Oze...
  • Taken for 1 to 6 months
  • September 17, 2022

For Type 2 Diabetes "I started Ozempic in January 2022. First week, I had extreme diarrhea with blood and mucus (always constipated before this). Endocrinologist told me he didn’t think it was Ozempic, but I went off it. Diarrhea, etc., continued. Ended up having to get a colonoscopy and was diagnosed with Ulcerative Colitis. Endocrinologist wanted to put me back on Ozempic. We figured the diarrhea, etc., was just the colitis. Started it back up five weeks ago. No diarrhea, back to constipation, nauseous every day, extreme fatigue. Also now diagnosed with Retinal Vasculitis. But my inflammatory markers are high. Not sure if this all started because of Ozempic. Just increased to 0.5 mg today, so we will see. It just seems like an odd coincidence. No appetite, but no weight loss either. Hair loss, but could be from colitis."

3 / 10
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  • C01...
  • Taken for less than 1 month
  • June 28, 2021

For Cardiovascular Risk Reduction "I am a week in; no appetite, nausea present but not as bad as the first three days on treatment, fatigue and constipation slightly. Will be back in a few weeks for update."

10 / 10
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  • Sme...
  • Taken for less than 1 month
  • July 9, 2019

For Type 2 Diabetes "Been on a few weeks at .25. Biggest side effect is sulfur burps, nauseous, and extreme fatigue that start the day after the weekly injection and lasts for a few days."

7 / 10
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  • Oze...
  • Taken for 6 months to 1 year
  • September 11, 2024

For Type 2 Diabetes "Weight loss 3 stone over 6 months. Fatigued at times. Irrationality."

8 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • March 3, 2025

For Cardiovascular Risk Reduction "Very sick and throwing up. Nauseous, sweats, and fatigue."

5 / 10
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  • MTV...
  • Taken for 1 to 6 months
  • February 23, 2025

For Type 2 Diabetes "So, in 4 months I have experienced 5-10 pounds weight loss. I feel fatigue, insomnia, sleepy, anxious, depression. I plan to continue use and see if these go away."

10 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • November 20, 2024

For Type 2 Diabetes "Extreme fatigue, no nausea, constipation, and diarrhea. Daily fatigue became very difficult to control. I had to lie down and rest 2 to 3 hours a day."

5 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • December 20, 2021

For Cardiovascular Risk Reduction "Had morning nausea and couldn’t drink much coffee and some fatigue after a few days, but it was worth it. Lost 30 pounds in 4 months and feel amazing."

10 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • June 20, 2025

For Type 2 Diabetes "I hate the side effects, fatigue and headaches, and irritable. Hard to do things."

6 / 10
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  • san...
  • Taken for 1 to 6 months
  • June 5, 2025

For Weight Loss (Obesity/Overweight) "Down 12 pounds in 4 weeks. Fatigue and stomach cramping are the side effects I am having most frequently."

8 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.