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Ozempic User Reviews & Ratings (Page 3)

Ozempic has an average rating of 6.6 out of 10 from a total of 1,511 reviews on Drugs.com. 52% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Ozempic

Commonly mentioned side effects
  • KCF...
  • Taken for 1 to 6 months
  • March 25, 2025

For Chronic Kidney Disease "I have been on Ozempic for the past 1 1/2 months. Gradually increased from 0.25 mg for 4 weeks, then 0.5 mg since then. After reading other reviews, the best tip I found was injecting into my thigh instead of the abdomen. Mild nausea, backache, and constipation the first 2 weeks, and nothing now but the feeling of fullness soon after eating, about 75% as much as usual. I have less interest in sugary or fried foods and have lost 12 pounds, about 2 pounds a week. At 74, my Type 2 diabetes is diet-controlled with good A1C's, so my primary use is for weight loss and preserving kidney functioning. The tiny 27 gauge needle is painless, just wish I had discovered Ozempic sooner!"

10 / 10
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  • Oze...
  • Taken for less than 1 month
  • May 14, 2023

For Weight Loss (Obesity/Overweight) "With just one 0.25 mg dose, I became very ill. Relentless nausea, vomiting, and explosive diarrhea, as well as unbearable stomach cramps. Needed to go to the ER for fluids and to check for pancreatitis. It’s now been 9 days since my first dose, and I still have relentless diarrhea, nausea, and disabling fatigue. I don’t want to eat. I didn’t want to take it in the first place but was ambushed by my kidney doctor. She told me that using Ozempic was a no-brainer and that I would just have a bit of nausea. If you have any gastrointestinal symptoms when taking any medicine, I would think three times about it before using it. I have read it can take up to a month for it to be flushed out of your body, but I am hoping and praying that these horrible side effects stop real soon."

1 / 10
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78 Report
  • Soo...
  • Taken for less than 1 month
  • July 8, 2021

For Cardiovascular Risk Reduction "I've been on Ozempic for just over a week now as part of a physician-run weight loss program. I was told to expect some GI upset, but I had no idea it would be this bad. Seven days after taking it, I started with diarrhea. One day after injection number 2 (2.5mg), I was up all night with diarrhea, nausea, severe reflux, belching, and eventually vomiting. Medications like Pepto can't seem to touch it. I am going to talk to the doctor next week and see what he thinks. I really don't think it is worth this kind of suffering."

2 / 10
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132 Report

Frequently asked questions

  • Ano...
  • February 26, 2022

For Type 2 Diabetes "Reading many of the reviews frightened me so I thought it was important to share my positive experience. I’ll first say, I’m horrified of needles. However, you can’t feel the needle at all, the medication going in sort of burns a bit, but that’s it! I’ve been on Ozempic for 5 months. I started at 254 lbs and started taking 0.25mg for 6 weeks. No side effects in the slightest. I also didn’t lose much either though because it is your body getting used to the medication rather than fixing your blood sugars. I then moved up to 0.5 and started seeing results with my weight and still no bad side effects other than eating less. I recently moved up to 1mg and am now down a total of 45 pounds in 5 months. Still no bad side effects. Eating has to be much more mechanical though because my hunger cues aren’t as strong, but no nausea. I would highly recommend this drug! Ps inject in your thighs, I believe this is the reason I’ve had no bad side effects my entire journey!"

10 / 10
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104 Report
  • Kay...
  • Taken for 1 to 6 months
  • August 16, 2020

For Type 2 Diabetes "With an A1C approaching 11, it was time to try something else in addition to Novolog and Tresiba, so my doctor added Ozempic. I also quit all alcohol and became a vegetarian. The first 3 weeks at 0.25 left me with a decreased appetite, nothing severe. The pounds started dropping off, fast forward 3 months and I am 22 lbs lighter. I love Ozempic, no bad side effects, and my insulin needs have decreased (not gone away), best of all, my A1C was 7! A lifestyle change helped a lot, but I credit Ozempic for many of these positive changes."

10 / 10
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  • Hel...
  • June 19, 2023

For Weight Loss (Obesity/Overweight) "After 1 year of taking this, I began suffering from severe abdominal pain. A couple of months later, while watching TV, I heard an Ozempic commercial that included warnings about gallbladder problems and pancreatitis. I immediately stopped using it and went to my doctor. I had to have my gallbladder removed. I gained the 50 pounds back that I had lost the previous year. Although it was effective, it was not worth the side effects."

1 / 10
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  • Shi...
  • May 13, 2021

For Cardiovascular Risk Reduction "I've been using Ozempic for a few months now, but the constipation has been extreme. Also, I have been having severe cramping at night and very yellow urine (only since starting Ozempic). I was told to drink more water, I got up to over 4 liters a day but still having severe cramping. Has anyone else had these symptoms which aren't on the list?"

3 / 10
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More FAQ

  • Dot...
  • Taken for less than 1 month
  • April 5, 2023

For Weight Loss (Obesity/Overweight) "I'm a 38-year-old man with type 2 diabetes and overweight. I was on metformin for three years and followed a good diet and exercise regime, but I couldn't lose weight. Although my blood sugars were perfect on metformin, weight was my issue. My doctor prescribed me Ozempic 0.25 mg, and I was very worried about the side effects. However, I started it recently anyway and injected it in the upper thigh once weekly. I had no issues other than constipation, which I overcame with laxatives and increased water intake. My appetite was reduced by 90%. I used to overeat, but now I can only manage two small meals a day. It's really working so far, but it's still early days. I'm in Ireland, and it costs €150 a month for four injections, which are covered by my medical card. I'll provide an updated review in three months to report how it has helped me lose weight on the scales."

9 / 10
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  • Ann...
  • Taken for 6 months to 1 year
  • September 9, 2019

For Type 2 Diabetes "Have been on Ozempic for 10 months. The first 3 months were very difficult with strong side effects. Mainly constant, but low level, nausea, occasional vomiting, and diarrhea (especially two days after the injection). However around month 3 the nausea and diarrhea subsided greatly and my appetite returned. I had lost weight very quickly (42 lbs in 3 months due to not really eating much). Had to take supplements for a while but am now eating well. The rapid weight loss led to telogen effluvium, a temporary hair loss condition. (I shed A LOT but never showed any baldness or anything). Currently, my weight is still down (I was taken off my blood pressure medication!), my blood counts are perfect, my hair is getting thick, and I eat normally. I now experience virtually no side effects. Really, really, glad I stuck out the side effects at the beginning."

7 / 10
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  • Hap...
  • Taken for 1 to 6 months
  • June 10, 2020

For Type 2 Diabetes "I've been using this off-label for weight loss for 3 months after consistent diet and exercise, and allegedly controlled Hashimoto's left me frustrated that I still couldn't lose weight. This drug has been amazing. I do still suffer from occasional headaches that are moderate to severe, and if I eat something I 'shouldn't,' there are usually digestive repercussions. But I'm down 15+ pounds in 3 months without any real change to my prior (very good) lifestyle. I lean into the days I'm not hungry and allow myself to eat on the days that I am. It is expensive, but there are great coupons. I will stay at the 0.5 dose until I reach my goal weight and then try to taper off."

10 / 10
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  • Ron...
  • Taken for 6 months to 1 year
  • September 8, 2019

For Type 2 Diabetes "I’ve been taking Ozempic for eight months. I’ve had minimal side effects on a 0.5mg dose. I’m taking this for weight loss with Metformin and a low-carb diet. I’ve lost 70 pounds from 265 lbs to 195 lbs. The change in my health has been remarkable. I call it the wonder drug."

10 / 10
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  • Nic...
  • October 25, 2020

For Cardiovascular Risk Reduction "I’ve been on Ozempic for a year and have lost 62 lbs. I’m at my goal weight!! Had trouble sleeping for the first few months, and would have some negative side effects when I increased my dose. But powered through and they went away. I was up to 1 mg but have been able to reduce to 0.75 mg. Super happy!!"

10 / 10
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  • Sar...
  • Taken for 1 to 6 months
  • April 7, 2020

For Type 2 Diabetes "Do not take this medication! After injecting the 0.5 mg dosage for two months, I began to have digestive issues. My doctor sent me for medical tests and found that I developed pancreatitis. I was told to stop using Ozempic immediately!"

1 / 10
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134 Report
  • Cry...
  • Taken for 1 to 2 years
  • March 30, 2023

For Weight Loss (Obesity/Overweight) "Started taking this medication a year or so ago. I haven't had any side effects, only positive ones! I started it due to struggling with my weight, even with working out constantly, and also being prediabetic. I have a history of Graves' disease and did an ablation on it with radioactive iodine, so it's nonexistent now. For a while now, I had a major problem with one-foot swelling with no help from any medicine. After taking Ozempic, I saw a dramatic decrease almost immediately, and it hasn't swollen up since starting Ozempic. I have also lost more than 50 lbs since starting. Truly thankful for this medication and its positive effects on my health."

10 / 10
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  • SHa...
  • Taken for less than 1 month
  • February 2, 2021

For Type 2 Diabetes "I feel that the best practice for this medicine would be to take about only 8-10 clicks (17 clicks = 0.25) for the first several weeks and then build yourself up to the full 0.25 dose. That way you can see what side effects you are going to experience and if they are tolerable or not. I took 0.25 and suffered from severe diarrhea for almost the full 7 days. Ended up in the hospital for the last 4 days until the side effects wore off. The only positive was that I lost almost 20lbs. I would be very careful taking this medicine."

1 / 10
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  • Mel...
  • Taken for 6 months to 1 year
  • February 25, 2021

For Cardiovascular Risk Reduction "I have been on Ozempic for weight loss for 10 months and I have lost 66 pounds!! This drug has been amazing. At first, I had a few side effects which included nausea and constipation but they did resolve. I noticed almost immediately how much better I felt on this drug. Not only was my appetite significantly decreased, I felt better overall, sort of like my metabolism was more even and my body utilized what I ate more efficiently. I lost my work insurance in November and also lost the coverage for Ozempic. This is the only downfall. I do have private insurance through HealthPartners but not one cent is covered by them. The price per month is around $800. With results this good, all insurance companies should be covering the cost 100% because it will save them millions, billions, even trillions possibly in the future. If they were smart, they would get behind this drug."

10 / 10
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  • HPa...
  • Taken for 1 to 6 months
  • June 11, 2020

For Cardiovascular Risk Reduction "In June of 2019, I was prescribed Ozempic for the first time for weight loss. I was given a sample in the office, and my prescription was sent to the pharmacy. My doctor was super optimistic, and I had seen drastic results in someone else I knew, but had been warned about the nausea. I am insulin resistant, have PCOS, and had gastric sleeve surgery in 2008. At the time I started the first 0.25 dose, I weighed 191.2 lbs. On the single pen, I did 4 weeks of 0.25 and 2 weeks of 0.5 doses. At the end of the 6th week, I weighed 173.8 lbs. That’s 17.4 lbs in 6 weeks! Of course, then insurance denied covering it moving forward, and I was unable to continue. But after a year, new bloodwork panels and some adjustments, somehow it has been approved, so I have started it again today! Hopeful for the same results! I had been taking a topamax/phentermine combo and was really disliking the pens, needle side effects, and the severe change in my tastebuds that it caused."

2 / 10
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  • Dan...
  • Taken for 1 to 6 months
  • March 24, 2019

For Type 2 Diabetes "I’ve been on this med for 7 weeks. I’ve lost 25 lbs and my daily blood sugars range from 60 - 90. I use it along with 500 mg Metformin. The first couple of weeks were hard with nausea and stomach cramps. I also had the headaches that others have mentioned in the first couple of days. In week 3, I increased from 0.25 to 0.50. Then came the diarrhea. It wasn't too bad, I was just happy that I could go. I’m now taking 1.0 and experiencing sulfuric burping. Ugh! After doing some research on home remedies to help with the burping, I’m trying a spoon of apple cider vinegar. If you can make it through the first few weeks and you can be somewhat disciplined, you will notice a huge difference in how you feel. In my opinion, the side effects are manageable when I compare the weight gain while taking Insulin. BTW - I’m not severely obese. Prior to being on this drug, my weight was 205, and I’m 5’9 and 47 years old. I hope this is helpful to someone."

9 / 10
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  • Bea...
  • Taken for 1 to 6 months
  • January 7, 2021

For Type 2 Diabetes "I have been on Ozempic for 6 months now. After the first few injections, I was so sick, vomiting, and diarrhea all the time. I called the doc and said I couldn’t take this anymore. Of course, I lost weight, as I couldn’t keep anything in me. I researched the medication itself to understand exactly what it was & how it worked. I decided to stay on it. My A1c was 8.8 when I started. 3 months later, 6.4. I am down 36 pounds. I have been exercising regularly for 3 months now, running 3.5 miles 5 times a week. The confidence and energy from the weight loss outweighs all the negative side effects in the beginning for me! Blood sugar control is excellent, and I suspect will only improve after the continued weight loss. I have stalled with weight loss twice now, but not giving up, and sticking to my exercise (changing it up a bit to gain more muscle to burn fat), I have been able to overcome the stalls and continue to lose. Complete game changer medication for me!!"

8 / 10
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  • val...
  • Taken for 1 to 6 months
  • May 29, 2020

For Cardiovascular Risk Reduction "I have been using this medication Ozempic for several months. My dose is 1mg per week. This medication has made me feel sick from my first dose. I've lost 15 lbs but have bloating, gas, burping, and most recently hiccups for over a week. I will not be using this medication anymore."

3 / 10
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110 Report
  • Lin...
  • Taken for 1 to 6 months
  • September 16, 2021

For Cardiovascular Risk Reduction "70 years old, not diabetic but obese at 170 lbs, 5’2” tall female. Started weekly on 4/29/2021 and as of 9/16/2021 I am at 140 lbs. Cannot eat as much as I used to or I get nauseous. Slow loss, about 7-8 lbs a month. Plateau every so often and then lose 3 lbs immediately. Extremely happy with results."

10 / 10
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  • Cin...
  • July 12, 2019

For Type 2 Diabetes "Well, so far and this is my 3rd week (I'm taking it for weight loss only) and I'm a little sick in my stomach, but no throwing up or bad gas. Fingers crossed, I hope I don't. Some of these side effects sound awful. I've lost about 2 pounds a week so far, and if this keeps up, I am going all the way with this. I take 0.25 so far. My doctor wanted me to try because I've lost 275 pounds all by myself, and I've been at a standstill. He wants me to get over this hump, so I'm trying this and so far so good. I hope it continues to be good for me. I hate it's not for some... And by the way, I've never had diabetes. So I'm taking it only for weight issues. I'm 50, and it's taken me 4 years to lose the 275lb."

8 / 10
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  • Kri...
  • Taken for less than 1 month
  • July 2, 2023

For Weight Loss (Obesity/Overweight) "This drug affects everyone differently, but for me, the side effects were too bad, and I had to stop after 2 weeks. It totally worked by killing my appetite and making me feel full, and after the first week, there were days I didn't even want to eat at all. I lost about 8 pounds in two weeks, which is great. However, during the 2nd week, I got the worst upset stomach of my life and almost went to the ER. I had intense diarrhea for an entire day, along with nausea, the chills, a swollen stomach, and then sweating. I had to take a sick day from work because I was also dizzy, and my heart was racing. It finally subsided about a day and a half, but it scared me so badly that I stopped taking the drug. Now I understand why it has a black box warning. I'm happy for the people who can use this without bad side effects. For me, I have a young child and demanding job. I can't go around with symptoms of food poisoning and try to act like I’m ok."

4 / 10
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  • Nay...
  • November 2, 2019

For Type 2 Diabetes "I have been on Ozempic for 13 weeks. I started out on 0.25 mg for 4 weeks, then moved up to 0.5 mg for 2 weeks, and then to the 1 mg. My A1C was 10.9 when I started the injection, and after 12 weeks, my A1C was 7.6. I have lost 34 lbs! I am feeling great, and I continue to lose weight. I am so thankful for this injection!"

10 / 10
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  • Los...
  • March 3, 2020

For Type 2 Diabetes "I have taken Ozempic for four days and have not experienced any of the symptoms others are saying they have had with one exception: I am very tired. I am eating a little less but do not feel like some say they can't eat at all. My blood sugar is down to 110, and I have lost three pounds. So far I see only good things. I hope it stays that way as I want to lose about 30 pounds and not take metformin. Hopeful!"

10 / 10
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