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Secukinumab and Upset Stomach: What Users Say

Brand names: Cosentyx

Upset stomach: mentioned by 8 users (3.1%)

Based on user experiences from 257 Secukinumab reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

pain 9.3%
itching 5.8%
fatigue 4.7%
diarrhea 3.9%
tiredness 3.9%
nausea 3.1%
upset stomach 3.1%
rash 2.7%
runny nose 2.7%
infection 2.3%

Reviews for Secukinumab

Commonly mentioned side effects
  • Jea...
  • Taken for 1 to 6 months
  • April 19, 2021

For Psoriatic Arthritis "I have had 2 drugs for psoriatic arthritis. One was a pill and made me very ill with stomach problems. The other was Cosentyx. Unfortunately, it also did not work for me. I had diarrhea for 4 months. My hair started to fall out, and now I have half the hair that I had before. Soon to be bald. Do not take this drug. If anyone else has taken it and had hair loss, please let me know. Thank you."

1 / 10
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49 Report
  • Fra...
  • Taken for 1 to 6 months
  • August 23, 2018

For Psoriatic Arthritis "I would give this medication a 1/10 for PsA and 7/10 for psoriasis. My psoriasis was and has been fairly mild for some time, but within 6 weeks of taking Cosentyx I was all clear pretty much. I took the 5-week loading dose and 4 consecutive months following that and was forced to stop due to switching insurances and trying to get re-approved. I did not experience any improvement in my PsA symptoms and, in fact, would say that my general joint ache, stiffness, and pain were worse. Besides seeing no improvement in my primary complaint, I have had 4-5 week-long sinus infections, a thrush infection, and several days in between with general stomach upset I hadn’t had prior to starting this medication. In switching insurances, they wanted me to try Enbrel first prior to reordering Cosentyx for some reason. I will try that as I am curious to see the difference in effectiveness as well as side effects. I’ll also be taking Enbrel through the winter, which will give me a better idea."

1 / 10
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22 Report
  • Ank...
  • Taken for less than 1 month
  • April 20, 2019

For Ankylosing Spondylitis "Started secukinumab 4 weeks ago, and what a load of rubbish it is. I was told that it is a brilliant medication, which after researching it, it's not at all. Was on Enbrel for 12 years, and it worked very well till they put me on Benepali (etanercept in UK), then after 3 months back on Enbrel brand, which just didn't seem to work anymore, and now on secukinumab. I feel like rubbish, I've got mouth sores, and my stomach just feels sore and very bloated. Drs will prescribe you anything when they get bonuses from prescribing it. I'm gonna ring the hospital and tell them I wanna stop it and try something else, as I just want my life back."

1 / 10
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20 Report

Frequently asked questions

  • Oki...
  • Taken for 1 to 2 years
  • August 6, 2019

For Plaque Psoriasis "My grandma had it bad. Then, at 49, I got it bad. Tried Humira, no luck. Now I've been on Cosentyx for about 14 months. The thick plaques are gone. The doctor did have to up me to 450 mg a month as of last week. It kind of makes my stomach hurt, but I'd rather have a tummy ache than be itching to death. I never knew how tough Granny was. This stuff isn't cheap, but I was ready to just die. Feel better now."

9 / 10
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14 Report
  • Oki...
  • Taken for 1 to 2 years
  • August 6, 2019

For Plaque Psoriasis "My grandma had it bad. Then, at 49, I got it bad. Tried Humira, no luck. Now I've been on Cosentyx for about 14 months. The thick plaques are gone. The doctor did have to up me to 450 mg a month as of last week. It kind of makes my stomach hurt, but I'd rather have a tummy ache than be itching to death. I never knew how tough Granny was. This stuff isn't cheap, but I was ready to just die. Feel better now."

9 / 10
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14 Report

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  • Ano...
  • Taken for 1 to 6 months
  • November 24, 2020

For Psoriatic Arthritis "This medication should come with a caution sign all over it! If I could leave a negative rating, I would. I lost 50 lbs in 2 months and went into liver failure. I was a skeleton. I couldn't walk or even eat. This drug gave me stomach aches that were so severe, I ended up in the hospital a couple of times. It was so hard for me to do anything, but I had to force myself if I wanted to survive. I nearly died from this drug, and I am only 18 years old. I ended up having Crohn's disease as well, but my doctor had no idea at the time of this medication. Therefore, the extreme stomach pain and nausea. The smell of food made me throw up. Before this drug, I was on Humira, then Enbrel, (then Cosentyx), then Stelara, and finally Cimzia. Now trying Simponi in hopes something will work. I even tried Xeljanz and no luck."

1 / 10
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9 Report
  • Pau...
  • Taken for 1 to 2 years
  • February 19, 2021

For Ankylosing Spondylitis "I have been using COSENTYX for 12 months. It was scary. Constant fatigue, stomach problems, terrible stagnation. I couldn’t go normally or roll over in bed. My spine and knees became completely flexed. Convulsions in the legs began."

1 / 10
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  • Lad...
  • Taken for 1 to 6 months
  • November 16, 2020

For Plaque Psoriasis "I was diagnosed with both psoriasis and eczema, so they put me on Cosentyx. So far, I have had 5 injections, but not much change yet, and now I am getting new spots. I go to the dermatologist in a couple of days, so I don't know what she will do next. I have had stomach upset after taking the injection, my nose runs like a faucet on and off. So we will see. I'm not sure what to think of this drug."

2 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.