Skyrizi User Reviews & Ratings (Page 2)
Skyrizi has an average rating of 8.1 out of 10 from a total of 67 reviews on Drugs.com. 75% of reviewers reported a positive experience, while 12% reported a negative experience.
Reviews for Skyrizi
- Chr...
- Taken for 6 months to 1 year
- May 23, 2025
For Crohn's Disease "Although my intestines look improved and inflammation markers are looking much better, I will be stopping very soon. My pain in my stomach and intestines, along with bloating, are much worse. Quality of life counts."
- Mon...
- Taken for 2 to 5 years
- March 5, 2025
For Plaque Psoriasis "Skyrizi keeps my 'P' in check. It is wonderful to only inject once every 12 weeks. I think it's important to share our side effects as well. I suddenly developed neuropathy in my toes after starting Skyrizi. It occurs only when I walk and gets progressively worse the longer I walk. As soon as I sit down, the numbness goes away. I have to weigh this permanent disability of not being able to walk like I used to with clear skin. I'll take the clear skin."
Frequently asked questions
- Who is the actress in the Skyrizi commercial?
- What are Monoclonal Antibodies and how do they work?
- What are IL-23 Inhibitors and how do they work?
- What's the dosing schedule for Skyrizi?
- Hel...
- Taken for 1 to 6 months
- March 26, 2024
For Plaque Psoriasis "I have currently taken three shots of Skyrizi prior to taking Skyrizi. I was on acitretin for about a year, to me, it seemed to have dried out all of my body parts, and at 41 years old, I was scared that I was basically ruined for the rest of my life. The dermatologist introduced me to Skyrizi as it helped my life tremendously."
- Ano...
- Taken for 1 to 2 years
- July 12, 2025
For Crohn's Disease "Truly has changed my life for the better. No side effects, and my Crohn's is pretty much under control with minimal flare-ups. My ONLY complaint is the dosing...8 weeks was not good for me as it didn't last in my system that long. It seems if the levels begin to dip a little, I am flaring. My doctor was able to get me approved (after 3 appeals with insurance) for every 6-week use. Since beginning a 6-week dosing interval, I have completely eliminated the need for budesonide. I hope this drug continues working for years to come. The only thing I wish that I knew about Skyrizi is there is not a test to check for antibodies like other biologics have. If I would have known this when picking my drug, that may have influenced my decision."
- tha...
- Taken for 1 to 6 months
- April 26, 2024
For Plaque Psoriasis "Wonder drug for me so far, been on it for about 3 months all active patches gone. Was extremely hesitant to touch systemics to the point my skin was horrendous. Only hyperpigmentation left behind now, hopefully that clears soon and the effects last. Haven't been ill, haven't had a single noticeable side effect."
- Dan...
- Taken for less than 1 month
- August 7, 2021
For Psoriasis "I have guttate psoriasis, about 70% of my body is covered. I just started Skyrizi and got both the starter injections in my stomach at the doctor's office. I have noticed some burning when I pee, some tiredness, flushing. I know my body has to get used to this medication. I’m glad I have some time off work for my body to adjust to this Skyrizi. The patches on my arms and legs are starting to dissipate after only 4 days."
More FAQ
- Does Skyrizi cause cancer?
- Can you drink alcohol while taking Skyrizi?
- Who makes Skyrizi and where is it made?
- Is Omvoh the same as Skyrizi?
- BiL...
- Taken for 1 to 2 years
- May 5, 2023
For Psoriasis "I started Skyrizi in May 2022 after my skin doctor had me try a number of drugs, including Enstilar. Enstilar was effective at first, but the psoriasis spread to my arms and legs so much we tried other creams and Otezla. After two weeks of starting Skyrizi, my psoriasis started to improve on my legs and arms. I have taken Skyrizi in August, November, and January. My skin doctor said I should keep using it because if I stop, the psoriasis might get worse. I am now in the second year of Skyrizi, and my psoriasis is 95% gone! Trying to research the issue of continued use after a full year or four doses."
- Sky...
- Taken for 1 to 2 years
- March 10, 2022
For Psoriasis "I’ve had psoriasis since I was 8 years old and have done every topical recommendation under the sun. I was on Otezla for a few years. Initially, it worked well, but I had a lot of side effects, and then it stopped working at all. I started Skyrizi a year ago and cannot be happier. My scalp is clear for the first time in 24 years, and all the visual plaques on my skin have resolved. I had no side effects from starting it, but have gotten two UTIs (which I have never had before) since being on it."
- Har...
- Taken for 6 months to 1 year
- September 24, 2024
For Psoriasis "I had psoriasis for 22 years. I am 70 years old, 80% covered. Tried all sorts of remedies, from natural to modern. Treatment was comfortable using UV light for over 15 years until I had my first COVID injection in 2020. Psoriasis went crazy for 2 years, no matter what I did. Psoriasis would flare more and more until my dermatologist recommended trying Skyrizi. The best. I did. Within a week, it cleared up my skin. No itchy skin, no lesions. Skin cleared. Much happier. Only side effects experienced for nine months since I had it: flu-like symptoms, flare-up of hives, nothing severe. I can live with that. I recommend it to all people suffering from psoriasis."
- Imp...
- Taken for 1 to 6 months
- April 4, 2024
For Plaque Psoriasis "I was about 40% covered with plaque. My onset occurred in 2018, and just kept taking new territory. I tried every topical OTC concoction that came to my attention. When I finally talked to a dermatologist, I was hopeful when she said she wanted to prescribe a biologic that I had already developed a good impression of, Skyrizi. I took the first of two introductory doses a few days before Christmas. By New Year's Day, I already noticed a slight lessening in the continuous sloughing off of dead skin. By the time I took the second intro dose near the end of January, I noticed a definite improvement in all my symptoms. The scales stopped falling altogether, and the itch was mostly gone. I had my 12th week injection recently, and my results have been completely astonishing! I was hoping so much that this would work, and it did! Finally, my suffering is behind me. I've had no side effects that I can definitely associate with this medication. Some mucous overproduction, but who knows?"
- Ell...
- Taken for 1 to 6 months
- September 10, 2024
For Psoriatic Arthritis "I have just taken my first 3-month maintenance dose. I have finally gotten ahead of the lesions on my scalp, back, and feet. The left foot is worse. I have tried everything from steroid creams and a scalp liquid that made my hair stuck to my head worse than the psoriasis, which was like concrete. I tried Otezla, which helped but not enough to now, with many lesions or plaques gone, I am finally in remission."
- Jil...
- Taken for 2 to 5 years
- September 6, 2023
For Psoriasis "I had psoriasis over most of my body. Flaking scales (especially my scalp) were making me not want to go out. Skyrizi has been life-changing for me! Two and a half years using it and my skin is absolutely clear. I haven't noticed any side effects and feel very healthy."
- Lif...
- Taken for 2 to 5 years
- April 18, 2025
For Plaque Psoriasis "Skyrizi has changed my life. I was 80 percent covered in psoriasis. I had tried everything. I had flakes everywhere. Even on my hands and my face. I was depressed beyond belief. All my free time went into researching how to stop psoriasis. Nothing worked. Until Skyrizi. I am 100 percent clear today. And I haven't thought about my flakes in years."
- 071...
- Taken for 2 to 5 years
- September 12, 2024
For Plaque Psoriasis "After being covered by psoriasis head to toe and trying all kinds of PO treatments and laser therapy, etc., my dermatologist finally told me about Skyrizi, a biologic that I would have to inject every 3 months. Within 2 weeks of my first injection, I was 100% free of psoriasis. Till today (9/12/24), I'm still in remission! I have been using this biologic for 4 years, and I couldn't be happier. I honestly sometimes forget I have this autoimmune disease. The only side effect that could or could not be linked to this medication is my immunity when it comes to COVID. My body's ability to fight this respiratory infection struggles, and I wonder if it's due to taking Skyrizi. My doctor just orders antivirals when I do test positive for Covid, and I recover really quickly that way. I 10000% would recommend Skyrizi if you are struggling with psoriasis. Don't give up, give this medication a try! Seriously."
- Jod...
- Taken for 1 to 2 years
- December 13, 2024
For Plaque Psoriasis "I had a diagnosis of plaque psoriasis that nothing seemed to help, that my dermatologist gave me, so they decided to try SKYRIZI. Three weeks after my first injection, I ended up with joint pain in my hands, ankles, knees, and neck. After my second injection shortly thereafter, my itching on my scalp and around my ears started to go away, shortly thereafter, all my joint pain went away. I’ve been on SKYRIZI for this entire year, and I have been cleared of all my scalp psoriasis in and out of my ears, and my joint pain is gone. I self-inject in the privacy of my home, which is very simple and easy to do, but I must thank AbbVie from the bottom of my heart because you really gave me my life back. Thank you again."
- Dve...
- Taken for 2 to 5 years
- August 19, 2023
"I started Skyrizi in 2020. I have inverse psoriasis, psoriatic arthritis, and HD. My inverse was so severe the impact on my life was devastating. Within months, my inverse was almost completely gone with very minor flares. My PSA greatly reduced, and I have not had a single lesion from HD. After 2 years on Skyrizi, I finally was able to see a rheumatoid arthritis specialist to treat my PSA. They added sulfasalazine to my treatment. I was completely cured of all 3. Due to insurance battles, I had to go without my injection for 6 months, and all my symptoms returned. I'm a 100% service-connected disabled veteran, and the VA refused to cover Skyrizi despite being unable to take methotrexate. I have had zero side effects. Zero increase in respiratory infections. In fact, despite multiple intimate contacts with individuals with active COVID, I did not get COVID. I used to get pneumonia annually, but since starting Skyrizi, I have not gotten pneumonia. It is a miracle cure for me."
- Kei...
- Taken for 1 to 2 years
- August 18, 2024
For Psoriasis "I have been taking Skyrizi 150 for over a year. I have psoriatic arthritis; my skin cleared up within 1 month or 2. My joint pain also subsided for the initial year. I have recently started having issues with increased joint pain, especially in the hand and elbow area. I will bring it up to my dermatologist next visit."
- Ama...
- Taken for 1 to 6 months
- May 28, 2024
For Plaque Psoriasis "I was taking Humira. However, it was not working as well as it had been, so my doctor switched me over to Skyrizi. I just did start my Skyrizi; so far, it has been different from the Humira in that it is a larger dosage, but otherwise, it has not worked for me as quickly as the Humira did. Unfortunately, I have still had worsening psoriatic arthritis pain."
- Kim...
- Taken for 1 to 6 months
- January 14, 2023
For Psoriasis "I have taken my starter dose, and it’s been about 3 months, and I still don’t see any results. This is my 2nd time giving this medication a try and getting the same results. I don’t get new spots, but my old spots don’t go away."
- Pet...
- Taken for 1 to 6 months
- July 21, 2025
For Psoriasis "Within 2 weeks of the first dose, my psoriasis cleared up nearly 100%, which is incredible. For about 2 weeks after every injection, I get a low-grade headache (not fever). Just a persistent, mildly annoying headache. After my 4th dose, within 4 days I developed severe inflammation around my sciatic nerve. Going on three weeks now of discomfort. I cannot say it is exactly in correlation, but I did nothing to bring it on. I have had issues not nearly as severe in the past few years with sciatica, but NOTHING close to this level of pain and discomfort. All in all, I am extremely happy with the medication's effects on my skin and general quality of life."
- BAR...
- Taken for 2 to 5 years
- June 17, 2025
For Plaque Psoriasis "After just one dose, I was 90% clear, and after the second dose, I was 100% clear, and I still am, 3 years later. I receive the medication at no charge and have very little side effects. The most significant is frequent bowel movements, which caused a slight weight loss. I would recommend this medication to anyone who suffers from this affliction."
- Ano...
- Taken for 1 to 6 months
- August 25, 2025
For Psoriatic Arthritis "I'm getting ready for my 3rd dose of Skyrizi. It has been working well. My psoriasis cleared up, and some of the arthritic pain has eased up, but my nose is running constantly, and I have sores and scabbing on both sides of my nose. Very frustrating at this point. Going to the doctor this week to see what needs to be done."
- Den...
- Taken for 1 to 2 years
- April 9, 2025
For Plaque Psoriasis "This has been a godsend for my husband, who developed type 2 diabetes, and with it came plaque psoriasis from head to foot. It affected his self-esteem, stopped him from going out socializing, and he started to become depressed. Our doctor sent him to James Cook Hospital in Middlesbrough in the UK to see a dermatologist, who, after countless creams, light treatments, and tablets, offered him Skyrizi. It has cleared his psoriasis up completely. He has been on it a year now, and the change in his mental health is phenomenal. He has it every 3 months, 4 times a year. The only side effect is that 2 days after he has had the injection, he gets flu-like symptoms, which clear up within a week. So, if you get the chance, Skyrizi is the answer, it’s a game changer."
- Ano...
- Taken for 1 to 6 months
- July 7, 2025
For Psoriatic Arthritis "Injection pen easy to use. Swelling in hands and feet has decreased after second injection of 150 mg. Plaque areas are minimal. On third dose, I immediately felt heat spread throughout my body. Felt a little dizzy and had back pain. Resolved by next morning."
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For Plaque Psoriasis "Worked great, but I had to stop taking due to upper respiratory infections. Before taking this, I never got an upper infection. My first injection, I wound up in the hospital with sepsis, double pneumonia incubated 3 days. I tried taking for a year but had to stop. Worked great."