Risankizumab and Tiredness: What Users Say

• Dan...
• Taken for less than 1 month
• August 7, 2021

Risankizumab for Psoriasis "I have guttate psoriasis, about 70% of my body is covered. I just started Skyrizi and got both the starter injections in my stomach at the doctor's office. I have noticed some burning when I pee, some tiredness, flushing. I know my body has to get used to this medication. I’m glad I have some time off work for my body to adjust to this Skyrizi. The patches on my arms and legs are starting to dissipate after only 4 days."

• Typ...
• Taken for 6 months to 1 year
• July 14, 2025

Risankizumab for Ulcerative Colitis "Began Skyrizi journey 7 months ago. 3 infusions and 2 OBI (on body injections) later, am in a much better place. When I started out, I was running to find a bathroom 20+ times a day. Now that I’m 7 months in, I’m under 3 times a day. The infusions and later OBI are easy to do. I am normally achy/tired for 1-2 days after the introduction of Skyrizi to my system. It improves after a few days. It normally takes 7-13 days before I see any effects from the medication. While I have a way still to go in healing, Skyrizi has eliminated the multiple times to the bathroom a day, the blood, and everything else associated with a UC flare. AbbVie (Skyrizi manufacturer) has financial assistance as well as supplying you with a Nurse Ambassador who helps you along the way. Skyrizi is my first biologic, and I’m grateful my doctor prescribed it. Looking forward to my next dose and to see what improvements it will bring."

• Kri...
• Taken for less than 1 month
• March 10, 2023

For Crohn's Disease "I've had one loading dose and experienced flu-like symptoms (tiredness, headache, body aches, nausea) for 2 days and then moderate to severe knee and back pain with fatigue."