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User Reviews for Quetiapine to treat Insomnia

Also known as: Seroquel, Seroquel XR

The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.

Quetiapine Rating Summary

User Ratings
35% (134)
20% (77)
13% (48)
7% (27)
4% (16)
6% (22)
2% (6)
2% (9)
3% (13)
7% (28)
7.7/10 Average Rating
380 ratings from 402 user reviews

Compare all 92 medications used in the treatment of Insomnia.

Reviews for Quetiapine

Heidi · Taken for 2 to 5 years June 16, 2020

“I take half a 25mg tablet for sleep and have been for a couple years now. Its been a miracle drug for me. Only 12.5mg does the trick. I cant imagine taking 300mg!? I'd never wake up. :)”

10 / 10
Kieran · Taken for 1 to 2 years June 14, 2020

“I was given seroquel to SLEEP, because I complained of insomnia ONE TIME. This drug is very addictive and made me very photosensitive, and I couldn't handle heat at all anymore. Those symptoms, at least photosensitivity, are not written in the side effects because of how rare they are. It took me one year without the drug to get back to normal.”

1 / 10
Roadbuzz · Taken for 6 months to 1 year May 31, 2020

“I've been on 200mg dose of quetiapine each night for a while now and it has its ups and downs. After 30 minutes I start to feel the effects and usually helps me sleep for at least 4 hours each night. It can make me sleep during the day though so I take naps. The downside is that I gained an insane amount of weight since starting it.”

6 / 10
TC · Taken for 6 months to 1 year May 19, 2020

“I feel like taking Seroquel MUST be like getting roofied. I took the 100mg and it literally knocked me out for 12 hours straight. Then after waking up, you're groggy for at least another 6 hours and are grumpy to people around you. I also got restless leg syndrome or some kind of VERY weird involuntary leg movements. I would ALSO always wake up in some kind of pain and it might be due to the fact that you're so knocked out your contorting your body in unusual positions while you sleep. I then got reduced halfway to the 50mg which did the SAME thing but with half of the SAME effects!!! Seroquel seems like a dangerous drug to me and I've been on a few.”

1 / 10
AA · Taken for 1 to 6 months May 8, 2020

“I was taking 100mg a night for insomnia. It worked at putting me to sleep but it gave me some intense memory issues. I was forgetting things, losing train of though mid sentence and forgetting what I was talking about. About 30 minutes after taking it I couldn't remember anything at all. I couldn't concentrate or focus at work. I took 25mg initially and it didn't put me to sleep, but it let me sleep through the night for about a week. Then I went up to 50mg and same thing.”

5 / 10
tiz4tggr · Taken for 1 to 6 months May 3, 2020

“Up until my gastric sleeve surgery in 2012, sleep was never an issue for me. If anything, I slept too much. Fast forward to 2020 and for the last 8 years I have suffered horrible to mild insomnia and even on a good night I may get 5 hours of sleep. I have tried all the common sleeping scripts out there along with some pretty serious anti anxiety drugs which ended with pretty bad results (a week in the hospital). In February of this year I went in for my normal physical except my normal doctor had left the practice and the new doc, filling in for her, was the one I got to see. I explained all that I wrote above and she reviewed my chart. She asked if anyone had ever suggested Quetiapine, which they hadn't. I'm currently on day 61 of taking 50mg a night with 7-9 hours a night being the new norm. I'm so thankful this wonderful doctor came into my life. I'm not sure if any other doctor would have even considered this drug. So far no adverse side effects or weight gain. :)”

9 / 10
Ash · Taken for 1 to 2 years May 2, 2020

“I was taking sequel for a long time all of a sudden I was getting bad stomachaches and was vomiting a lot is this a sleeping pill?”

1 / 10
Medman · Taken for less than 1 month April 10, 2020

“This medicine Seroquel will help you get to sleep at 100mg at bedtime. But will also affect your dopamine negatively and make you groggy.”

6 / 10
Ed · Taken for 10 years or more February 25, 2020

“I have been taking quitiapine for more than 15 years for bipolar but especially for insomnia. Lately my brain feels sick and tired and sometimes anxious all too often. I tried stop taking the quetiapine but it is absolutely impossible to sleep without it. I am taking 200mg which is necessary. I understand that l can go insane without adequate sleep. My doctor up till now has not given me a solution. Do you have any suggestions l could try as l am caught between a rock and a hard place.”

10 / 10
Kpsan February 21, 2020

“I have to start by stating every drug effects everyone differently and some respond positively to certain meds and others had horrible reviews. For me, this drug quetiapine literally saved my life. I was going on 3 weeks of no sleep from chronic stress. I was manic and could not sleep no matter what I tried. I took Xanax, over the counter antihistamines, downloaded meditation apps, etc. I was literally on the verge of the end of my life until my parents forced me to go to behavioral health hospital. At intake, I was in the worst shape of my life, lost so much weight and looked like a complete paranoid schizophrenic out of his mind. The psychiatrist told me that they were going to give me something to knock me out and I asked what. She said seroquel and I asked what kind of drug is that and she said an antipsychotic. I took 100 mg and sure enough, I finally got rest. It did take a while to get back to normal again, about a month but I really believe if I hadn’t been given this drug, it would have been the end of me”

10 / 10
bobcat · Taken for 5 to 10 years February 15, 2020

“Seroquel at 25mg is a miracle sleep inducer. I took it for 10 years every night. One night I was away and without the pill. Guess what, horrible sleep! Lately I'm taking 50mg as 25mg seems to give now 6.5 vs 8 hours of sleep. Just like Tramadol fixed my depression, seroquel fixed my sleep. These two meds don't send your psychiatrist to conferences in Maui and Tahiti, hence the lack of interest.”

10 / 10
BorninPS · Taken for less than 1 month February 15, 2020

“I have depression coupled with panic disorder. I have been on 20 mg of paroxetine coupled with Xanax then as of late Clonopin for the past 30 years. I started feeling very depressed and drugged out lately, so I cut down very, very slowly on my benzodiazepines, and I switched to Saroquel for my chronic and I mean chronic insomnia . It’s very strange, during the day I feel as if a white hot glow light is on deep in my brain making me more aware, but it is not attached to my nervous system meaning it does not make my heart beat faster. I have only been on it for three nights but I have slept all the way through those three nights, what is funny is for about an hour it gives me restless leg syndrome!”

9 / 10
Banta · Taken for 5 to 10 years February 14, 2020

“I'm on 300mg at night, I've been on this dose for 6 years. I tend to have vivid, colorful dreams and then wake up exhausted. Even after the alarm goes off after 7 to 8 hours sleep, I have to set the alarm for at least another 2 hours. I find that I'm more sensitive to sunlight and my metabolism has decreased. I find weight gain a problem and my skin has become inflamed with dermatitis. I also have found if I miss a tablet, I end up having withdrawals. It does help with sleep but has a few side affects attached to it I was tried on so many antidepressants but unfortunately they had an absolute adverse effect on me, so I couldn't take them and I'm left with seroquel.”

5 / 10
Frank February 8, 2020

“I am prescribed 50mg dose Seroquel at night about 45min. before bed for sleep. It also stops my restless leg syndrome! Not what it is usually prescribed for but it does the trick. I have been using it for 3 years with no side effects.”

10 / 10
IDRK80 · Taken for 2 to 5 years February 6, 2020

“On Pristiq 100mg for general depression but my doctor started me on 25mg seroquel for nagging insomnia. At first it was fantastic and worked within 30 minutes. I've now been taking it for over 2 years but a warning! Your body will start to tolerate it. Your 25mg dose soon becomes 50mg, which then doubled to 100mg and now some nights I need 200mg to fully knock me out. And it takes about an hour. 25mg is 2/10ths stuff all but 200 turns you into a flat emotionless droid. This drug is great at what it can do but I feel trapped on it and can't see any real alternative.”

7 / 10
Ugghh · Taken for 1 to 2 years January 31, 2020

“Haven't had my med quetiapine for 3 days now and I have NOT been able to sleep. I have been prescribed it for over a year now and I recently moved and haven't managed to get a new prescription. This is causing hallucinating at this point. I have tried sleep aids, NyQuil, nothing helps me sleep. If you're on this med and looking to get off, good luck sleeping again.”

2 / 10
Pillhead97 · Taken for less than 1 month January 17, 2020

“I think quetiapine 25mg is best for insomnia”

Chris · Taken for 1 to 6 months January 13, 2020

“The quetiapine is difficult for me to get off. I started on a dose of 50mg in November now up to 400mg. It was prescribed for sleep along with klonopin. I am tapering of Klonopin. So, that is why the does of Seroquel went up. I suffer insomnia horribly. Now afraid how long it will take to stop using this drug. Have had intrusive thoughts since starting both these meds.”

2 / 10
Nomoreinsomnia · Taken for 6 months to 1 year January 11, 2020

“Excellent for my insomnia. Prescribed 25 to 50 mg short acting dose of Seroquel for past seven months. 25 mg works best for my insomnia. It has been a Godsend.”

10 / 10
Sdh January 10, 2020

“On this for sleep problems and depression, made me sleep, but I was almost comatose. Had no recollection of sleeping, no dreams. Didn't like that complete switch off”

8 / 10
Meliss · Taken for less than 1 month December 31, 2019

“Seroquel is Wonderful for sleep. Honestly, the best I've ever tried. No more nightmares, either.”

10 / 10
nardis · Taken for 2 to 5 years December 19, 2019

“I've been using a dose of 25 mg quetiapine for sleep for 4 years. Combined with a low carb diet, I haven't gained any weight. The medication does cause a bit of drowsiness if taken late. Taken before 10:30 pm, I can be sleeping by 11:30 and up by 8am with limited grogginess. It's been a cheap, reliable and non-addictive medication for me, but I'm hoping there's no long term complications!”

10 / 10
Jaidee · Taken for less than 1 month December 9, 2019

“I was thinking too much and could not get to sleep. I take 25mg of seroquel before bed and within 30 minutes I struggle to stay awake and it relaxes me. The next day I still have anxiety but I've only been taking this for 1 week.”

10 / 10
Squeaky · Taken for 2 to 5 years November 25, 2019

“My insomnia is genetic as everyone in my family seems to have it, but have no other diagnosis as to why. We sleep very heavy 2 hours at a time with periods of being awake 1-3 hours in between. Which makes working hard as we often only get 2-4 hours sleep a night. After being tried on many different over the counter and prescription drugs which either did not work or had to have the dose increased every few weeks my Dr. suggested this . I have been taking this for insomnia for 3 years. Unlike other medicines I have never had to increase my dose and the only adverse side effect I noticed was some weight gain. I take less than the clinical dose for many depressed patients as I take only 25 mg a night an hour before bed. This was my miracle! After 2-3 years of 2-4 hours sleep a night I was beginning to literally loose my mind due to lack of sleep. I now sleep 6-8 hoours straight every night,( with occasional bathroom trips).”

9 / 10
J · Taken for 1 to 2 years November 20, 2019

“I take 25 mg quetiapine at night along with zopiclone 10, this makes me sleep , deep sleep for 7 or 8 hours, I do not sleep on zopiclone alone so I have to take quetiapine to sleep well, so I HIGHLY recommend it for people who can't sleep.”

9 / 10

Learn more about Insomnia

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Symptoms and treatments Health Center

Mayo Clinic Reference

ICD-10 CM Clinical Codes (External)