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User Reviews for Quetiapine

Also known as: Seroquel, Seroquel XR

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Learn more about Quetiapine.

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29%(40)
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16%(22)
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15%(20)
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8%(10)
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6%(8)
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8%(11)
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10%(14)

Quetiapine Rating Summary

7.0/10 Average Rating

141 Ratings with 113 User Reviews

What next?Compare all 217 medications used in the treatment of Depression.

Reviews for Quetiapine to treat Depression

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"Worsen my depression a lot. I cound not find a reason cause I have been on effexor from 1998 (20 years) And effexor works great. I took seroquel a 100 mg once a day for 3 weeks. Look out!"

Voice from Poland (taken for less than 1 month) December 10, 2017

1 users found this comment helpful.
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"I was prescribed Seroquel for PPDin early 2016 after having my 2nd child. I had a past history of severe post partum depression with my 1st birth and my 2nd birth was no different. I had the perfect storm for a mental breakdown. I had just had my baby 1 month early via emergency C-section after going into labor from a very close family member unexpectedly passing away. I had horrible symptoms...racing thoughts, no sleep, no appetite, increased heart rate, and worst of all, intrusive and disturbing thoughts. My psychiatrist, prescribed me 50mg of Seroquel to take only at night or as needed so I could sleep. Seroquel is the only medication that I have ever taken that can put me to sleep. Thank God for this medication!"

   
9.0

Aer661 December 9, 2017

0 users found this comment helpful.
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Seroquel XR (quetiapine): "I've been on this for 4-5 years and it is my rock. It literally helps me so much, I couldn't have made it through high school without it. Honestly it's what helped me through my suicidal phases. I still get them but it's not as intense and I don't try and act on it anymore."

   
10

Alexis.M November 6, 2017

3 users found this comment helpful.
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"I have been taking Seroquel at a low dose (50mg) for about 10 years; for insomnia and depression (to augment another mood stabilizer). It generally works very well. I fall asleep almost immediately and have uninterrupted sleep. I do have some grogginess in the morning but it generally wears off within 30-60 minutes. The only other potential side effect I've experienced is elevated cholesterol, but I do not know if the seroquel is causing it; my internist believes it may be hereditary. It's available as a generic and is very inexpensive with my insurance. Overall I find it's a good med."

   
8.0

Matt B. October 16, 2017

5 users found this comment helpful.
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"Seroquel is the only medication that has really worked for me. I have major depression and possible bipolar disorder and it’s helped lessen my degree of depression and help me get on a more steady path. Psychotic symptoms are under control. I thought I had treatment resistant depression for a long time until I tried this. The only problem is the sedation. I’m on XR and I don’t have the sedation as bad."

   
8.0

JH123 October 8, 2017

3 users found this comment helpful.
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"My doctor prescribed this for depression. Mood- wise, it helped and I also slept like a rock. BUT In a matter of 8 months I managed to gain 25 lbs... which my doctor did NOT tell me was a huge side effect. I stopped taking the medication and now I cannot sleep at all. I have been off of it for three weeks and still no luck."

   
3.0

Jenn8894 (taken for 6 months to 1 year) September 3, 2017

4 users found this comment helpful.
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"First of all, for all the people writing reviews that haven't been on this drug for AT LEAST 4-6 WEEKS your reviews are almost invalid, this drug is as two-faced as many make it out to be and for those people they just aren't giving it enough time to see both sides of it. I have been on and off Seroquel for a few years now and currently taking 150mg at night for the past 3 months. It helped with anxiety and sleep which was great! I was less intimidated and anxious at school and with friends. However, it seriously affected my mood, constantly shifting from agitated to blunted, my concentration, my dreams, weight and eventually, over the course of about six weeks, caused one of the most serious relapses in my depression in years. Be careful!"

   
3.0

Someguywithdepressionduh (taken for 2 to 5 years) July 6, 2017

11 users found this comment helpful.
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"My doctor had hoped that Seroquel could help my depression but Seroquel XR caused a bizarre condition where I couldn't stop flailing my arms and legs. Now I take 600 mgs of regular Seroquel to help me sleep at night. Does it help with my depression? I don't think so. At least not to a significant degree. But it does help me sleep!"

   
5.0

Sad Amy (taken for 5 to 10 years) May 29, 2017

5 users found this comment helpful.
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"I was diagnosed with Delusional Jealousy in November 2016. I was utterly convinced my wife was cheating on me despite no evidence to support this irrational belief. The lack of evidence just made me even more suspicious. I was out of control. Taking Prozac and Lorazepam to try and control the anxiety was making things worse. A private Psychiatrist diagnosed me and prescribed quetiapine 300mg. The first 2 weeks were a bit groggy but I kept fit, ate healthily and went to bed early. The results were astonishing. I was immediately so much calmer and rational. At the very least this drug saved my marriage and at best it has probably saved my life. Yes I'm hungry all the time and have to be careful with food, but it's a small price to pay."

QuetiapineBoy (taken for 6 months to 1 year) May 24, 2017

18 users found this comment helpful.
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Seroquel XR (quetiapine): "I was on this medication for around 3 years at different doses, anywhere from 50 mgs to 600 mgs. It was a very good medicine and helped a lot with my anxiety and depression and really calmed me down and was very helpful, but the weight gain was a killer. I would try to go off over and over and would have to keep going back to it because I would be in such bad shape without it. I had a love/hate relationship with it. I became pre-diabetic while on it. I finally was able to go off and stay off at one point. It's a great drug, but the side effects are horrible as far as weight gain."

   
8.0

Gastroparesis Girl (taken for 2 to 5 years) May 20, 2017

10 users found this comment helpful.
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"I was prescribed Seroquel when I had just recently been put on Buspar for anxiety and was not feeling beneficial effects yet. It was a break glass in case of emergency medication for me. Thankfully, the Buspar did not take too long to kick in and I only had to take a few of the Seroquel. It has been a few years since then and I still had the mostly full bottle with me. My new doctor decided to stop refilling my Trazodone for 4 months and so I started taking Seroquel again at night to help me sleep. It did help me sleep and did wonders for my anxiety and occasional racing thoughts, however over the course of a month, I managed to gain 40 lbs. I have since run out and am happily taking Trazodone again, but I have not lost any of this weight. I was not terribly excited about my weight before and now I'm nearing 200 lbs, which is not a healthy weight for me."

   
5.0

stephthepanda (taken for 1 to 6 months) April 30, 2017

4 users found this comment helpful.
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"I've been on quetiapine for a few years, I have had weight gain and I've put on a lot weight and now I'm diabetic type 2, but for me its been a small price to pay, I've have tried a lot of different drugs (antidepressants) over many years but for me quetiapine has saved my life in many ways before taking this drug I was very ill, I wanted to die not because I hated life or anything like that but I wanted to stop my awful thoughts I couldn't cope with anything in life, many times I was seeing things my life was hell, not sleeping, not going out fearful all the time, Even though I still have problems I never go anywhere on my own not even out by the front door,I know this drug has given me a small part of my life back."

   
10

lillybuff63 (taken for 5 to 10 years) March 10, 2017

17 users found this comment helpful.
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"Excellent substitute to benzos for sleep. Take 25-50mg a night, very helpful. No major side effects at this low dose, just much better sleep. Takes about an hour to make me drowsy."

   
8.0

Canada345 (taken for 1 to 2 years) February 19, 2017

17 users found this comment helpful.
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"I'm 32 years old, bipolar, OCD tendencies. Have been taking Seroquel XR for over a week now. At first it seemed to trigger a manic episode that lasted for 5 days. For someone who typically spends most of his time on the depressive side, this was heaven. LOL I take 100mg a day just before bed time, have no trouble getting to sleep, am able to stay asleep and don't find it too difficult to wake up. I normally have consuming and unwarranted anxiety. This has been greatly suppressed. I find it much easier to control my anger and in general my emotions have become much more stable. There have been no negative side-effects. I still feel like I need an additional anti-depressant as my normal "base level" is too low but am otherwise satisfied"

   
8.0

SGP666 (taken for less than 1 month) February 5, 2017

14 users found this comment helpful.
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Seroquel XR (quetiapine): "I have depression with anxious disitress.My extremely racing thoughts would typically whip me up into a panicky state, sometimes with outbursts of irrational anger. Seroquel XR works fantastically to ease that racing mind, to a more 'normal'and useful pace. Side effects are virtually absent: the XR doesn't floor me like immediate release Seroquel did. I can function and think well. Seroquel XR is a good medicine. It also helps with my depression."

   
10

Global Man January 25, 2017

26 users found this comment helpful.
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"I took this medicine with lamotragine to treat major depression and speculated bipolar disorder. I think it worked well, it got me out of a bad fog, but it made me so tired. I had to sleep for a tleast 12 hours. If anyone let me, I'd probably sleep for 24. For most of the time I was taking 50mg. Then we upped it to 100mg and I was starting to sleep through my alarms, I was being late for work. So I took myself off of it gradually. I didn't have the money to back to the phsychiatrist. Anyhow, I got off of it, it's been a good 8 or so months. And the depression is back..or at least starting up again. I'm thinking that my only option is to go back on this medicine..but maybe only take 25 mg doses since it makes me so tired. Is this a bad idea?"

   
5.0

Era766 January 17, 2017

6 users found this comment helpful.
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"I been on this med for 3 weeks, and feel much better but in constant fear of weight gain ."

   
5.0

abica December 21, 2016

8 users found this comment helpful.
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"I take 300mg of serequol xr at night time with antidepressants it puts me to sleep as I wouldn't be able to however I'm knocked out until the morning if I don't take it everyday I get major withdrawals symptoms even if it's on 48 hrs so will be interesting in seeing how I get off it over the next couple of years but has improved sleep and mood"

   
8.0

Teddymack November 24, 2016

7 users found this comment helpful.
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"I've been on this drug for four years, and I will admit, it did help me out at first. I was deeply depressed and going through some major life changing situations. As this calmed down and I developed spiritually, emotionally and mentally, I gradually decreased the dose. I was on 100mg the first year, the second year, 50mg, the third, 25mg, and the fourth, 12.5mg (cutting the 25mg pill in half.) I just got off of it two days ago, and I feel like a new person. I had no idea how much it tampered with my mind. I was in a fog for FOUR YEARS. Although I'm sleep deprived, achy, and irritable from the withdrawals (this med's withdrawals are heinous) I feel better than I have in four years. I do not recommend this drug- save your mind!"

   
2.0

Elaine_M November 21, 2016

16 users found this comment helpful.
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"I am 65 and have PTSD from the loss of my son. I was prescribed Xanax and Klonipin for a few yrs but they did not deal with the panic attacks that I was experiencing. I cannot take SSRIs due to side effects, so I mentioned the Seroquel to my doctor who said it did have a mild anti depressant effect. I take .25 mg in the morning, and 3 of them at night . No weight gain, I am very active. If anything, my appetite has fallen. I sleep 8 hrs REM sleep and don't really need as much of the xanax or klonipin now. The Seroquel has helped me function greatly and won't allow the panic to set in. So, I am happy with it."

   
10

mtb3333 (taken for 1 to 6 months) October 26, 2016

23 users found this comment helpful.
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"I've been on this for a few weeks for insomnia. It is TERRIBLE. It gives me a severe headache every morning and has made my depression increase threefold. I absolutely hate this medication. It has actually made me feel more mentally unstable."

   
1.0

Deanne marie October 12, 2016

12 users found this comment helpful.
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Seroquel XR (quetiapine): "I am diagnosed with borderline personality disorder with psychotic features. I was put in intensive out patient care after going to the Emergency Room for intense auditory hallucinations that were so malicious I feared for my own life. Lost my job and everything. Seroquel has given me hope as well as lorazepam for my anxiety. To me seroquel is a miracle drug for its antipsychotic features as well as depression. I'm having to up the dosage lately because my voices are creeping back in. Searching for further pychiactric help but right now I'm stable and I thought that would be impossible. Sharing a good experience. Thanks for reading."

   
9.0

Keylimeisbomb (taken for 1 to 6 months) October 5, 2016

42 users found this comment helpful.
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Seroquel XR (quetiapine): "I have only been on Seroquel XR for about a week at 50mg. My doctor prescribed it as an adjunct to Remeron to treat anxiety, depression, paranoia, and insomnia. I also take gabapentin, atenolol, and Xanax. When the Seroquel XR works, it WORKS. I can feel it sedating me two hours after I take it. I've been sleeping eight and nine hours a night, which has not happened in a very, very long time. It's effective at neutralizing both anxiety and depression. BUT... it doesn't last 24 hours for me; it only lasts about 15. Once it wears off my anxiety and depression return with a vengeance. Makes for a very rough 8 or 9 hours until I can take it again."

   
6.0

This is Kris (taken for less than 1 month) August 15, 2016

38 users found this comment helpful.
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"I am going to agree with the last comment, however I find it hard to eat/keep on weight after major surgery & cancer- so the weight gain is GREAT for me, personally. I used to mainly use marijuana to help me eat (and to help calm me down), but smoking it is terrible for my lungs (I already have COPD from smoking marijuana for 15 years) This helps me get to sleep, seems to "even-out" my moods, but I can't take it during the day for anxiety because it messes me up too much. I use clonazepam (successfully) during the day, when needed. At first I didn't want to take seroquel, but it is definitely worth a try!! Better than every other "nightmarish" antidepressant I have ever tried!!"

   
9.0

Worth*a*Try (taken for 6 months to 1 year) July 28, 2016

13 users found this comment helpful.
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"Pros: Zapped my depression, cured my insomnia and keeps my mood calm and steady. Cons: Weight gain, still need Valium for anxiety."

   
8.0

shotsInWashington July 26, 2016

21 users found this comment helpful.
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