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Quetiapine for Depression User Reviews (Page 3)

Brand names: Seroquel, Seroquel XR

Reviews for Quetiapine

Commonly mentioned side effects
  • Ind...
  • Taken for 1 to 2 years
  • September 25, 2013

Quetiapine "I have been on 400 mg of Seroquel XR along with my antidepressant for more than 1 year. Initially, the medicine worked great for my stress, delusions, and helped me sleep well at night. Lately, the anxiety has returned, and I have severe anxiety during the daytime. At night, I pass out, so I don't feel much. However, this medicine has caused me to gain a lot of weight. I would say I have gained about 25 pounds since starting the medicine."

8 / 10
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  • JCK...
  • Taken for 1 to 6 months
  • January 16, 2024

"I have bipolar disorder, insomnia, ADHD, severe depression, and anxiety, panic attacks, OCD, and at times I get manic. I got prescribed 100 mg a day, and it helps with sleep, anger, and even my appetite. I take Vyvanse in the morning, and I take quetiapine an hour before bed, and it’s been a lifesaver. It’s helped with my depression and anxiety as well. I wish I had found it sooner than I did. I’m very grateful for the help. My quality of life has gotten so much better."

10 / 10
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  • Hap...
  • April 10, 2012

Quetiapine "After a 6-week period of a severe depressive episode with panic attacks and extreme anxiety, I checked myself into the hospital. The doctor completely changed my meds to Prozac, Wellbutrin, Klonopin, and at bedtime, 10 mg Ambien and 400 mg Seroquel. This combination has worked wonders for me. I started falling and staying asleep for a good 8 hours, my ruminating has stopped almost completely, and my depression has really lifted. I attribute a lot of that to the Seroquel, in that it augments the effects of my antidepressants, stops my mind from racing, and has me sleeping well. The two side effects I've had are grogginess (which has gotten better) and the munchies. I keep fresh fruits and veggies handy at night to snack on instead of junk."

9 / 10
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Frequently asked questions

  • Dee...
  • Taken for 1 to 6 months
  • May 11, 2019

"Found quetiapine very helpful as a sleep aid for my daughter at a low dose, but as I increased the dose, it made her anxiety and depression worsen. This is our seventh medication. I am now proceeding with pharmacogenetic testing through saliva in hopes that through testing her DNA, we can find an appropriate medication match for my daughter. Hope this helps someone out there."

2 / 10
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  • Stu...
  • Taken for less than 1 month
  • January 18, 2020

"I had major depression, suicidal idealization, major anxiety. 1 x 50 mg tablet at night, feeling much better within 24 hours. Some lingering tiredness and more sleep required, instead of 7-8 hours, need 8-10 hours. Years on various SSRIs, 10%-15% improvement at best. Valdoxin, Prozac, Zoloft, etc."

9 / 10
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  • Tom...
  • Taken for 2 to 5 years
  • January 29, 2018

Quetiapine "First, I'm not schizophrenic, nor have I been diagnosed as bipolar. I take this for drug-induced anxiety. I was initially given Seroquel XR because I exhibited rapid speech and a disorganized thought pattern during my continual intoxication by kratom. Kratom is a 'natural,' legal substance with opioid and stimulant qualities. Well, I noticed right off that Seroquel XR calmed my racing thoughts. I saw this as a benefit, but the next move was for me to quit using kratom. I got help for that via SUBOXONE, which I'm still on. My whole life and way of thinking took a sharp turn for the better. I remain on the Seroquel XR, along with the SUBOXONE. When I questioned the continued need for Seroquel XR, my doctor simply said, 'Look, you're doing great. Why change a thing?' And he's right. So Seroquel XR remains a part of my daily recipe for success."

9 / 10
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  • mtb...
  • Taken for 1 to 6 months
  • October 26, 2016

"I am 65 and have PTSD from the loss of my son. I was prescribed Xanax and Klonopin for a few years, but they did not deal with the panic attacks that I was experiencing. I cannot take SSRIs due to side effects, so I mentioned the Seroquel to my doctor, who said it did have a mild antidepressant effect. I take .25 mg in the morning and 3 of them at night. No weight gain, I am very active. If anything, my appetite has fallen. I sleep 8 hours of REM sleep and don't really need as much of the Xanax or Klonopin now. The Seroquel has helped me function greatly and won't allow the panic to set in. So, I am happy with it."

10 / 10
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  • Anonymous
  • November 26, 2010

Quetiapine "I've been taking Seroquel (100 mgs) for 2 months now. It's been great. I've had treatment-resistant depression for years and have taken every antidepressant on the market with little to no help. I was running out of energy and time. After trying Abilify (bad akathisia), Lamictal (still taking), we tried Seroquel, and within a 2-week period, I was back in life. What a wonderful gift. I'm very thankful. Also, I've had refractory insomnia that has been alleviated as well."

10 / 10
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  • sic...
  • Taken for 1 to 6 months
  • August 26, 2015

Quetiapine "Hate this med. Constantly sick on it. Stomach pain, severe diarrhea, passing out, severe dizziness, and unable to wake up. Hungry for food all the time. Nasty taste in mouth. Thirsty all the time. Can't motivate myself to do anything. This was on the lowest dose available. Won't take it ever again, don't care what my doctor says. No way."

1 / 10
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  • Ale...
  • November 6, 2017

Quetiapine "I've been on this for 4-5 years, and it is my rock. It literally helps me so much, I couldn't have made it through high school without it. Honestly, it's what helped me through my suicidal phases. I still get them, but it's not as intense, and I don't try to act on it anymore."

10 / 10
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  • Ang...
  • Taken for 2 to 5 years
  • June 22, 2018

"I have had depression on and off for the last 30 years of my life. I have been on many different types of antidepressants, but it never worked well, and I got all sorts of side effects like anxiety and a jittery feeling in the body. My depression gets worse when I don’t get enough sleep or can’t fall asleep for a few days. Three years ago, my doctor prescribed Seroquel medication to me, and it really helped me. I started with 50 mg, and now I am taking 150 mg: 50 mg of the XR and 100 mg of the regular release for the last few months. This combination helps me fall asleep and go back to sleep when I wake up. This has no side effects on me besides feeling great in the morning."

9 / 10
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  • Rou...
  • Taken for less than 1 month
  • December 18, 2018

"My daughter is 20, and she is on this drug for psychosis after major depression. After 1 week of 50 mg, I do not see a change at all. So after 1 week, the dosage has been increased to 100 mg. Today she had the worst and scariest episode. She was yelling, screaming, shaking, crying, and scared, so scared. I really don't know what to do. Can someone tell me, is this normal after 1 week of being on the drug? And when will this start working and decrease the symptoms? I don't know how much more I can handle."

2 / 10
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  • 55 ...
  • October 17, 2009

Quetiapine "It seems to be very helpful for my depression, anxiety, adult ADD, and overall mood. Seroquel XR also seems to have no noticeable side effects, and I sleep great. I've been taking 2 of the 300 mg, in the evening, now for 2 months."

9 / 10
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  • Ang...
  • April 11, 2012

Quetiapine "Was taken off Geodon because of nighttime anxiety and put on Seroquel XR. I feel so unmotivated. Sedated. I no longer feel better by afternoon when it's time to take it again. I dread the next dose. Haven't felt this depressed in a while."

1 / 10
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  • Ms ...
  • Taken for less than 1 month
  • November 10, 2015

"I have been taking this for 3 weeks, and I completely came off Valium I was on for 11 months on the day of taking this. I noticed a change in the 2nd week, and I feel calmer and have the ability to make more concise and clear decisions. I do not act out of anger anymore. I will take my time to analyze a situation, and before time has gone, I realize the situation no longer bothers me! Great med, low dose for depression, anger issues!"

10 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • March 30, 2016

Quetiapine "It was mainly prescribed as a sleep aid, in addition to its antidepressant qualities. I was on regular Seroquel and now on XL as I have trouble staying asleep. It's slightly better. I'm getting 6 hours of sleep a night. I am not usually groggy or snowed by this, maybe once per 30 doses. I'm okay with it. Only downside is cost (XL is brand)."

8 / 10
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  • Mop...
  • June 6, 2019

"Seroquel did slightly help with my anxiety and depression, more so depression, though the doctor prescribed me this for the diagnosis of bipolar (later found out I was misdiagnosed after different second opinion). Side effects experienced: fatigue, dizziness/lightheadedness (normally experience this quite often, but Seroquel increased frequency), weight gain/increased appetite. Gained 10 lbs within 3-4 months, and I'm the type of person that can eat as much as I want and won't gain anything, but on Seroquel I definitely did. This messed with my mental health even more and in the end caused me more depression and anxiety. Seroquel also made me incredibly irritable. It was very easy for me to get upset and angry. I also got some odd feeling of restlessness in my body after each time I took the next pill, especially at 100 mg (stopped at 150 mg, my highest dose), and going to sleep was the only way the feeling went away. The withdrawal was awful, as I experienced insomnia for 2 weeks. Overall...I did not like Seroquel."

2 / 10
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  • Amj...
  • Taken for 1 to 2 years
  • January 13, 2022

"I'm happy, I feel happy, I have a sweet, sweet feeling. Everything is easy and sweet. Yes, I'm talking about quetiapine. This is one of the best mood stabilizers, and everything solves in depression. I have taken 25 mg every day at bedtime. I'm able to sleep easily without tension and think more positively. When I wake up in the morning, I feel such a sweet feeling, I feel more energetic power in my everyday life. I would like to thank the medicine makers who made this."

10 / 10
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  • Mer...
  • Taken for 6 months to 1 year
  • April 26, 2018

"I suffer from depression after losing my husband two years ago. I tried other medication but had side effects I couldn't tolerate. Since being on this medication, my depression is not as severe, and I am finally able to cope with life. It helps me to have a good night's sleep, but I find in order to wake up without feeling groggy, I must take it around 7 pm if I am waking up between 5:30 and 6:30 in the morning. (I take 50 mg). The only side effect I have had is restless leg syndrome (RLS) on occasion. Other than that, it's the best medication I have tried for depression."

8 / 10
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  • Arr...
  • Taken for 1 to 6 months
  • November 11, 2015

Quetiapine "My experience on Seroquel nearly cost me my job as it turned me into a zombie! Since going off the drug, I am fully functional. My head is clear and I have energy to do things. I cannot believe my doctor prescribed me an antipsychotic drug such as Seroquel. Colleagues observing me thought I had undergone a major personality disorder. I have been off it for a month now and not missing it one bit."

1 / 10
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  • Sha...
  • August 22, 2011

Quetiapine "I was diagnosed with mild bipolar disorder, depression, post-traumatic stress disorder, and generalized anxiety. Most of my adult life, I had insomnia. I use Seroquel 50 mg once a day and Celexa. The Seroquel stopped the racing thoughts, generalized anxiety, allowed me to sleep well at night, and I'm able to think things through rationally. Seroquel is the best medicine for me. I love it. I used to only take it at night as I would fall asleep immediately, but now I'm able to take it during the day."

10 / 10
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  • lil...
  • Taken for 5 to 10 years
  • March 10, 2017

"I've been on quetiapine for a few years. I have had weight gain, and I've put on a lot of weight, and now I'm diabetic type 2. But for me, it's been a small price to pay. I've tried a lot of different drugs (antidepressants) over many years, but for me, quetiapine has saved my life in many ways. Before taking this drug, I was very ill. I wanted to die, not because I hated life or anything like that, but I wanted to stop my awful thoughts. I couldn't cope with anything in life. Many times I was seeing things, my life was hell. Not sleeping, not going out, fearful all the time. Even though I still have problems, I never go anywhere on my own, not even out by the front door. I know this drug has given me a small part of my life back."

10 / 10
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  • Dou...
  • July 12, 2015

"I'm 38, have struggled with depression, and been suicidal, searching for help since I was 13-14. Finally found a psychiatrist who understood. She prescribed 100 Seroquel daily and ECT. Only had 3 out of 4 ECT treatments. That, together with Seroquel, I have never felt better or more stable in my life. Still have issues with anxiety when writing essays. Was prescribed a 25 mg tablet to put under my tongue. It works great. I had trouble at first with medication as I was taking it morning and night. I would be falling asleep at pre-start meetings at work. I now take it nightly before bed. I sleep great and wake up refreshed. This drug works. You just have to work out the right time to take it."

10 / 10
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  • Dan...
  • Taken for 6 months to 1 year
  • July 17, 2021

Quetiapine "I have been on the Seroquel XR 50 mgs, and it absolutely works better than anything I have ever taken for anxiety. And I've taken every SSRI under the sun, Valium, clonidine, gabapentin, and Vistaril all in the past. This medication is a lifesaver. It does make me feel drowsy 3-4 hours after taking it, so it should be taken around dinner time. My doc first started me on it first thing in the morning, and I was dozing off by noon. But other than that, it has been a lifesaver. Almost no anxiety, I sleep better, my appetite is good, my mood is good and confident. For me, it even helps to relax my muscles. I'm so glad my doc took a chance and prescribed this medication off-label for my anxiety. It has given me a new lease on life."

10 / 10
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  • Joh...
  • Taken for 2 to 5 years
  • January 21, 2021

"I take 700 mg of quetiapine daily as it’s the only way of preventing me from harming myself. It’s like being mentally awake in a sleeping body. I have been on this dosage for years and no sign of this decreasing while my mental state continues the way it is. I was a fit, sporty guy before taking it and now feel like a zombie."

3 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.