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Prucalopride for Chronic Idiopathic Constipation User Reviews (Page 4)

Brand names: Motegrity

Reviews for Prucalopride

Commonly mentioned side effects
  • rob...
  • Taken for 1 to 6 months
  • June 21, 2023

"I was on Resolor 1 mg for 3 months. It has been helpful for regular bowel movements. However, on 5th June, I developed for the first time a supraventricular tachycardia with a heartbeat of an average of 130. Now I have stopped taking it. I need views on whether my SVT was caused by Resolor 1 mg."

7 / 10
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  • Ame...
  • Taken for 1 to 6 months
  • July 28, 2021

"I started on 1 mg a day for a week. They gave me a slight headache but made me feel so, so sick for about 4 days. I couldn’t get out of bed for one of those days. So I took half a mg in the morning + in the evening to help ease into them. I also experienced strong waves in my stomach. But once I got through the initial shock to my system, they are working like a charm. I’m glad I personally persisted with them."

9 / 10
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  • lan...
  • Taken for 1 to 6 months
  • September 9, 2021

"Developed severe IBS-C following emergency gynae surgery. Apparently, that can bring on IBS. 4 years of 6-12 Laxido a day. Frequent pseudo-obstructions. Linzess stopped working within a week. Started prucalopride 1 mg for 2 weeks with some success - didn't stop my Laxido but adjusted it as needed. Upped to 2 mg. Now on 4 Laxido a day to keep it very soft. Have many fewer problems now. Also, for 4 years, couldn't eat any veg or fruit as I obstructed, as my bowel couldn't move it. Now I have 2-4 portions a day. Am I cured? No, but this is a big improvement, and my quality of life has greatly improved. I have been on it about 6 months. I must say it appears to work more month by month, I am now starting to have a few days on 3 Laxido. I suggest having some osmotic laxatives if your constipation is very bad, along with prucalopride. It isn't contraindicated in most people, but check with your doctor first. My doctor told me to stop initially, but I did it with Linzess and paid for months after."

9 / 10
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Frequently asked questions

  • Dow...
  • Taken for less than 1 month
  • July 4, 2021

"I was given samples of Motegrity because I have pelvic floor dysfunction, IBS-C, gastritis, and a bit of gastric emptying delay. I wanted this to work so badly! The first day produced a perfect BM, but I have migraines and thought one was coming on all day. The next day, BM again, but I started having anxiety over dying! What? Depression hit the third day. I’m done! Going to just take senna. Nothing else works."

3 / 10
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  • Ron...
  • Taken for less than 1 month
  • August 11, 2021

"At first, I was excited because I have bloated for a long time, and I started to fart after an hour. Then suddenly it starts working and I have to run to the toilet and have this horrible diarrhea and palpitations to the extreme. My stomach growls nonstop and I even stay in the toilet for an hour... I feel dehydrated. I'll stop this... worst med."

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • March 9, 2023

"I've suffered from severe constipation for years, nothing has ever really helped me. I took prucalopride once around a month and a half ago and had a really bad headache, nausea, sweats, and abdominal pain and couldn't get off the toilet all night. I took it again around 2 weeks later and had the same side effects but didn't work for me as well as it did the first time around. I started taking it again last night along with 2 other laxatives I was told to take and my god, I haven't gotten off the toilet since! Side effects have not been as bad for me this time around, the only problem is my stomach is rumbling so much, but I have no appetite! I'm hoping they will calm down soon, and my appetite will come back."

6 / 10
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  • now...
  • Taken for 2 to 5 years
  • October 29, 2022

"I have been on the highest dose for about 2 years now. It worked amazingly in the beginning, but now it doesn't really work because I have to drink 2 laxatives every day. I have no side effects. I don't know what I'm going to do as I don't think there's a cure for my situation."

7 / 10
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  • Wee...
  • Taken for less than 1 month
  • November 20, 2020

"I just started to eat prucalopride because of chronic constipation. I eat this medication with the stomach medication (Dexilant). Now I feel very stomach upset. I have diarrhea after half an hour of eating the medication. Feel a little headache. I don’t know if it’s that side effect of this medication or the stomach medication."

3 / 10
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  • Gas...
  • August 21, 2022

"I was given Resolor/prucalopride 2 mg to try to help my slow bowel system from gastroparesis. I had read the reviews on here, so I decided to only take half the pill, 1 mg. I took it with water around 11 pm, so this way if it did well, I could sleep. I laid down and was on my phone just relaxing when about 40 minutes later I started feeling my stomach gurgle. I got up and went to the restroom. Sure enough, it already gave me a bowel movement. It didn't end there. I was starting to feel nauseous. I paced around because my stomach was becoming so upset there was no way I could lay down and just fall asleep. I ended up throwing up all of my food from that day plus diarrhea at the same time! It was awful! I'm jealous of all the people who've had the great experience with this pill, but I'll NEVER take it again. I was up until 5 am sick. I've laid in bed all day because I still feel sick. If you try this, take as little as possible the first time! You'll be grateful you did if it goes bad!"

2 / 10
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  • Joa...
  • Taken for less than 1 month
  • February 25, 2023

"I’ve been taking this medicine for eight days now. I have had a headache for the first two days and chronic abdominal pain the whole time. I have reduced my dose to 1 ml, and I am hoping that my side effects will stop. Has anyone else suffered this bad?"

1 / 10
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  • Ann...
  • Taken for less than 1 month
  • May 16, 2023

Prucalopride "I wanted to share my story as I just took my first dose of this medication tonight. I'm crossing my fingers because nothing else has been effective, and I am currently down to 107 pounds at a height of 5'5". During the lockdown, I was exposed to toxins in a home I had recently moved into. After four months of being there, I experienced a wide range of symptoms, including severe gastric emptying delay and dysfunction in my colon. Whenever I eat, I suffer from severe consequences. At the moment, I'm on my third round of Xifaxan, which costs $2500 for each two-week treatment, and my gastroenterologist suspects it might be small intestinal bacterial overgrowth (SIBO) as well. Xifaxan helps with reducing inflammation and bloating, but unfortunately, my colon isn't improving. Currently, the only thing I am able to eat without major issues is eggs, and even then, I have to use a daily enema. I also have eosinophilic esophagitis (EOE) and have undergone several surgeries involving scopes, biopsies of the esophageal area, and laparoscopic exploratory surgery. As I enter my third year with these conditions, they are getting worse."

6 / 10
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  • Sha...
  • December 28, 2019

Prucalopride "I have experienced constipation for many years. I take Motegrity along with a magnesium supplement every day. (Not at the same time) No side effects for me. I’m finally normal. Thank you, Motegrity."

8 / 10
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  • Cur...
  • Taken for 6 months to 1 year
  • February 20, 2024

Prucalopride "Relieved my constipation. Am going daily now when I used to only go once a week. Changed my life."

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • February 26, 2022

Prucalopride "I have taken it 3 times, and each time the same side effects, all within 15 minutes of taking the medication. Bloating was the worst, along with stomach ache, nausea, and severe headache!! No thanks."

1 / 10
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  • Reb...
  • Taken for less than 1 month
  • December 23, 2021

Prucalopride "Doesn't work! I have extremely slow-moving bowels, and absolutely nothing works. I had high hopes for this! I have had no side effects at all, but it just doesn't work. Day 6 and nothing."

1 / 10
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  • Kat...
  • Taken for less than 1 month
  • May 7, 2019

"Did not work. After about a week, I felt so hopeless and sad, and that's not me at all. I stopped it immediately and will never use it again. Definitely didn't work at all for constipation."

1 / 10
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  • ZEN...
  • Taken for less than 1 month
  • June 16, 2020

"The side effects are intolerable: headaches, nausea, abdominal and back pain, general feeling of feeling completely ill."

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • July 7, 2019

"The first week I took it was amazing. I was going daily, but the second week and so on, I was back to my normal of hardly ever going. So frustrating. Back to the specialist this month."

4 / 10
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  • Ric...
  • Taken for less than 1 month
  • August 10, 2019

"I tried 2 mg prucalopride, and it worked the next day, however, terrible stomach pains and gas lasted and I still have gas and an upset stomach going on to day 3 since using it only once."

2 / 10
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  • Mar...
  • Taken for 1 to 6 months
  • March 9, 2022

Prucalopride "3 months of 2 mg. Plus Miralax 2 x daily. Stool very soft, never empty enough for colonoscopy."

5 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

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