Compazine and Anxiety: What Users Say (Page 3)

• Mea...
• Taken for less than 1 month
• July 27, 2018

For Nausea/Vomiting "I went to the hospital due to a severe migraine and nausea. I was given Compazine via I.V. Oh dear! I immediately began having chattering teeth, severe anxiety, and uncontrollable clenching of teeth. I also could not remain still, as if I wanted to get out of there as fast as I could. I called the nurse in, and the response was, 'Oh, yeah, you feel kinda outta it?' Well, yes, it will pass, don't worry! ARE YOU SERIOUS RIGHT NOW! It's just by the grace of God that I got home safely. My teeth continued to chatter, and I could not sit still! I had to go back to the ER to get medicine to counter the side effects. I feel a little better now. Day 2 and still feel out of it. I WILL NEVER TAKE Compazine again!"

• Abb...
• November 15, 2017

For Nausea/Vomiting "Was given Compazine for the first time in the ER. It was mixed in a cocktail for my headache. After 3 minutes, I started feeling uneasy, and I started to have a full panic attack. I’ve never felt that in my life! I ripped my IV out of my arm and started kicking the walls and stomping, they thought I was insane! I told them it was the medicine, they didn’t do anything, just released me, and I felt like my skin was crawling for 3 days. Was the absolute worst experience of my whole life!"

• Bea...
• Taken for less than 1 month
• June 27, 2019

For Nausea/Vomiting "I wish I could give this drug 0/10 stars. This is not a drug that I would give to my worst enemy-and I have tried many drugs for migraines! I was given this with the migraine cocktail in the ER, which also includes Benadryl and Toradol. I experienced extreme anxiety and restlessness. I wanted to rip the IV out of my arm and run out of the hospital... not that I could have done this anyway because it caused me to have extrapyramidal and dystonic side effects! When I got discharged from the ER, this was the worst night of my life. My friend had to sleep over because I was freaking out. The side effects lasted for 2 days."

• Yva...
• June 24, 2019

For Nausea/Vomiting "Worst medication! About 9 years ago, when I was in high school, I caught mono and was vomiting a few times when my mother took me to an ER/urgent care. They gave me an IV with Compazine and a prescription for home. It wasn't until maybe the second day I couldn't move my muscles. I had ZERO movement in my body and could barely walk or get dressed. Nothing. I constantly shook like I was having a seizure. I couldn't sleep for an entire week! Let alone sit still. It was constant anxiety. It's like I lost all ability to relax. It was a living hell. When I went back to the urgent care, the lady literally told me it was mono. I went home and continued to take this medication, not knowing I had a severe allergic reaction. Finally, I went back again and got a doctor who actually knew what was going on! He told me to stop taking Compazine ASAP. People get PERMANENT damage from this! It took over a month for this to leave my system, and until this day, the anxiety is still there."

• Zan...
• Taken for less than 1 month
• March 27, 2021

For Nausea/Vomiting "Do NOT use Compazine!! I went to the ER for a severe migraine that lasted a week. They put me on Compazine, and within just a few minutes, I was shaking uncontrollably, couldn’t keep still, and had extreme anxiety, like if I didn’t leave the hospital RIGHT AWAY, my entire life would just go down the toilet. This was the only time I ever ripped out an IV. I called the nurse in, and I could only mumble “Oh God, what did you do to me” over and over again. After some of these other reviews, I count myself lucky that my symptoms only lasted a single night and the migraine did go away. But still, I will never take it again!"

• Pat...
• Taken for less than 1 month
• May 16, 2019

For Nausea/Vomiting "It is absolutely horrible. I went into the ER yesterday with a bad headache on one side. They wanted to give me some cocktail that included Compazine and Benadryl combined. I said no. I should have done my research on Compazine prior to getting it intravenously. The worst mistake of my life. I had shakes, anxiety, which I don't have, the worst dry mouth of my life, that I almost choked on my sugar pill. I felt like it had been out in the desert for a year. I could not keep my mouth moist fast enough. It has been almost 24 hours, and I'm still not back to 100 percent yet. That drug is toxic. I would never, I don't care how much pain I'm in, ever take that drug."

• mom...
• Taken for less than 1 month
• October 31, 2022

For Nausea/Vomiting "It has been a little over six months since I was given Compazine through my IV when I had a migraine, and I am still not right. It’s important to note that prior to the injection, I have never had any problems with mental health besides intermittent anxiety (mild). I went to the ER for a severe migraine that had been lasting a few days. I was given Compazine through my IV for the pain. I immediately had the worst panic attack of my life. I can’t even compare it to other panic attacks I’ve had because it was profoundly horrific. Wanting to escape, suicidal thoughts, terror, wanting to rip the IV out of my arm, and extreme restlessness. I have had debilitating anxiety ever since. After reading many of the reviews, I see most people feel better after a few days, but that hasn’t been the case for me. I have now been struggling with never feeling at peace or comfort. I can no longer feel love, happiness, joy, or even experience laughter. I walked out of that hospital a different person. Please avoid."

• Poo...
• Taken for less than 1 month
• March 23, 2019

For Nausea/Vomiting "I went to the ER last night with nausea and vomiting. I was given Zofran, but it had soon worn off. I told the doctor, and he said he would give me something else. The nurse came in with the Compazine. She gave it to me through my IV. Within minutes, I started to feel really jittery and restless! I started to become anxious and fidgety, and I wanted to rip my IV out of my arm. The medicine worked for the nausea, but it's definitely not worth the side effects! It was the worst feeling ever!!! It has been 21 hours since, and I still don't feel right. The symptoms have calmed down a lot, but I'm still not 100%."

• Poo...
• Taken for less than 1 month
• March 23, 2019

For Nausea/Vomiting "I went to the ER last night with nausea and vomiting. I was given Zofran, but it had soon worn off. I told the doctor, and he said he would give me something else. The nurse came in with the Compazine. She gave it to me through my IV. Within minutes, I started to feel really jittery and restless! I started to become anxious and fidgety, and I wanted to rip my IV out of my arm. The medicine worked for the nausea, but it's definitely not worth the side effects! It was the worst feeling ever!!! It has been 21 hours since, and I still don't feel right. The symptoms have calmed down a lot, but I'm still not 100%."

• Ang...
• Taken for less than 1 month
• May 17, 2018

For Nausea/Vomiting "I have been given Compazine in my IV, and it was one of the most horrible experiences of my life! It almost immediately made me very anxious, I wanted to pull my IV out and just get out of the hospital! I felt zombie-like, and my face went numb. I had side effects like these for about 3 days! Never again will I take Compazine!"

• Hor...
• Taken for less than 1 month
• September 18, 2016

For Nausea/Vomiting "The absolute worst experience with an antiemetic I have ever had. I literally panicked in the hospital to the point I almost pulled my IV out. Zofran stopped working for my hyperemesis gravidarum, but I would rather live with nausea and vomiting day in and out than feel the uncontrolled anxiety and restlessness I felt with Compazine!"

• Cat...
• Taken for less than 1 month
• April 4, 2019

For Nausea/Vomiting "I thought I had the flu, so I went to the ER to get tested. It came back negative, but since I had a migraine, they gave me a “headache cocktail” which my sister had a bad reaction to, but I had forgotten (after all, I had a migraine and couldn't think straight). I got the IV meds, and one of them was Compazine...the awful liquid itself. Immediately, I had trouble getting comfortable, and my throat felt like I had a shrunken airway, but the doctors said it was just anxiety. So, it’s 4 in the morning, and I’m stumbling around the hospital waiting for my prescription and my stepdad to come pick me up, and I’m falling asleep any time I sit down. As soon as I got home, I fell into bed and couldn’t sleep unless my legs were writhing around. Then I slept off and on for almost 20 hours. I sweated most of the medication out, thank goodness, but I’ve never had anything like it happen before. I was by myself and was terrified. Why is this medication even still given?!?"

• Ahr...
• Taken for less than 1 month
• October 31, 2016

For Nausea/Vomiting "I had been suffering from severe nausea and vomiting on and off, including migraine, fever, and flank pain. It was my second time in the ER, so they gave me Compazine and I'd never had it, it relieved my nausea and migraine, but I started feeling so restless. I was freaking out, like I wanted to rip out my IV and leave and run away. Then they told me it's a side effect, and I already suffered from severe anxiety, it made it 1000x worse. I had the worst time trying to sleep, then had the weirdest dreams of my life. They gave me morphine shortly after, which calmed me a little and took the rest of my pain away, but I was hoping it'd honestly put me out. 24 hours later, and I still feel that restlessness in my body, but it's so much better than it was."

• bul...
• Taken for less than 1 month
• June 18, 2019

For Nausea/Vomiting "I suffer from severe headaches on occasion, and usually Excedrin will do the trick. I had a headache several months ago that was there for 3 days. I finally broke down and went to the ER. They gave me Compazine and put me in a waiting room. Within five minutes, I felt terrified, like I had to get away. I told my wife to tell them to get my IV off me, or I would rip it out of my arm. They let me sign out AMA, and I fled the hospital. For several hours after, I felt like the walls were closing in and doom was imminent. I hate this medication and will NEVER take it again. Beware!!!"

• SPh...
• May 28, 2016

For Nausea/Vomiting "I went to the ER for stomach pains and nausea. I am allergic to so many pain medicines that there is little I can take. They gave me Compazine, and as they put it in my IV, they told me it could cause severe anxiety in some people. Well, I can tell you now, it was horrific. I have had one major panic attack in my life, and this was 20 times worse. I started pulling off my clothes and ripped the IV out. They had to give me a big dose of Benadryl to 'reverse' the effects. Please, please think twice and consider other choices before taking this!"

• Jca...
• August 21, 2019

For Anxiety "I really wish I would have read these comments before I was given Compazine through an IV. Only let them give me half the dose after I started feeling like I was going to pass out. Worst experience of my life. My heart rate was 174 for hours, and I couldn't stop pacing back and forth for hours. Anxiety at its very worst. I honestly thought I was going to black out constantly and also felt like I was going to rip my IV out of my arm, take my clothes off, and just run. I wish this drug upon no one. The hospital should be sued for giving this drug to patients. Stay away... I pray no one else goes through this. It's been 30 hours, and I do feel better than I did, but I still feel a bit jumpy and not myself..."

• Jca...
• August 21, 2019

For Anxiety "I really wish I would have read these comments before I was given Compazine through an IV. Only let them give me half the dose after I started feeling like I was going to pass out. Worst experience of my life. My heart rate was 174 for hours, and I couldn't stop pacing back and forth for hours. Anxiety at its very worst. I honestly thought I was going to black out constantly and also felt like I was going to rip my IV out of my arm, take my clothes off, and just run. I wish this drug upon no one. The hospital should be sued for giving this drug to patients. Stay away... I pray no one else goes through this. It's been 30 hours, and I do feel better than I did, but I still feel a bit jumpy and not myself..."

• Bea...
• August 9, 2019

For Nausea/Vomiting "My doc gave me this medication over 20 years ago for nausea. I ended up having an allergic reaction. I had anxiety, and I couldn’t relax all day. I went to the hospital because of dystonia. Awful day. It also induced OCD, which I have been dealing with ever since. Has this terrible medication triggered OCD in others?"

• Ksw...
• Taken for less than 1 month
• July 21, 2019

For Nausea/Vomiting "I was given this awful medication in a migraine cocktail. Within minutes, I was so anxious that I yanked my IV out and ran out of the hospital room. For hours, I couldn't stop moving my legs. It's been 3 days, and I'm still so anxious. I made the pharmacy write in notes that I was allergic to Compazine - prochlorperazine, so this never happens again."

• Hor...
• Taken for less than 1 month
• April 28, 2023

For Anxiety "I remember thinking I wanted my migraines back because of how this med made me feel. I still feel horrible and jittery and panicky. When they gave it to me, I wanted to run, and I couldn’t sit still, and I was freaking out. I do not recommend this at all, ever."

• Jen...
• May 9, 2016

For Nausea/Vomiting "I was given this through an IV in the ER. I had terrible nausea, and Zofran didn't touch it. Even though Compazine did take my nausea away, it left me incredibly groggy yet restless. I spent the entire rest of the day in a haze. I've never abused drugs, but I would imagine this is how you would feel when coming off of some sort of high, yet it lasts all day long. I kept feeling angry and anxious as well. I would much rather have nausea and will never take this medicine again!"

• Sup...
• August 22, 2019

For Nausea/Vomiting "I feel for all of you very much. All of those bad experiences, I also had. Plus, doctors and nurses don't seem to care, at least most don't. About 13 years ago, I went to the ER for nausea, vomiting, and diarrhea. I didn't feel well when I went in. As soon as they put Compazine in my IV, I felt terrible panic, restlessness, anxiety. I could not sit, lay down, or stay in one place for more than 5 minutes. I pulled my IV out and started running to my friend. I thought maybe I had a stroke. I didn't know. My friend tried to talk to the doctors. I was outside, I couldn't do anything to feel any better. I waited to die. I was afraid I would hurt someone. I was one of the top weightlifters in the world. I started banging my head as hard as I could on the concrete wall. Then I went back in the hospital bleeding. I thought then the doctors would do something to help me. They called the police, my friend got me home. I was worse. I took some Xanax. I still have anxiety from that experience."

• Nug...
• July 10, 2019

For Nausea/Vomiting "I was on this thread a while ago to see if people had a similar experience, and I’m just now deciding to post because I remember how horrible it was. I went into the ER with pancreatitis, and instead of promethazine, they decided to do Compazine. I wish I could go back in time and stop the nurse from administering it. They pushed it with IV dilaudid, so it took a bit for me to feel the negative effects, but long story short: crippling anxiety, sweats, uncontrolled movement (dystonia), insomnia, the list goes on. Didn’t sleep for 56 hours, and the only thing that even helped a little was walking. I walked that entire time. This medication is the worst."

• Anonymous
• September 26, 2019

For Nausea/Vomiting "I was given this Compazine last night for a migraine. I knew I shouldn’t have taken it because I’ve had a bad experience with Reglan. The doctor assured me that it was far less likely to happen, and I even asked the nurse to push it in slowly. It took a few minutes to kick in, but once it did, I knew the feeling all too well. Extreme anxiety and just an uncontrollable feeling of panic. You want to move around because you can’t think, and you want to escape, but then you’re afraid to move. They offered to give me Benadryl, but I was just afraid at that point. It eventually mellowed out slightly, and they discharged me. I went home and had an issue sleeping because I couldn’t sit still or stay asleep long. Next day, it’s been a little over 12 hours, and I still feel restless and so tired. I’ve tried to sleep, but I feel like I have to keep moving. I wasn’t even able to go to work. I would have preferred having my migraine. ONLY GET Toradol AND Zofran OR Benadryl for your migraines."

• Nom...
• Taken for less than 1 month
• October 9, 2019

For Nausea/Vomiting "Just like all the others. I was given this plus Benadryl in the ER to treat headache and nausea. I soon wanted to claw out the IV, and I had this horrible sense of dread, like I was going to die. I couldn't think of anything but wanting to get out of that room. After getting home, I was terrified to be alone. Finally slept it off mostly after several hours. Still feel off and jumpy 12 hours later. Never taking this medication ever again."