Compazine and Anxiety: What Users Say (Page 2)

• Kla...
• Taken for less than 1 month
• May 28, 2019

For Nausea/Vomiting "Went to ER for a migraine I could not control. Was given Compazine by IV. Instantly felt like I was crawling out of my skin, couldn't sit still. Went home, and a few hours later ended back at the ER due to uncontrollable body movements. When I got there, the doctor told me it was dystonia, which is a side effect reaction from the medication Compazine, which is irreversible. It has been almost 7 months since this day, and I still have uncontrollable muscle movements and severe anxiety. Please do not take this drug, my life has been hell ever since."

• PBa...
• Taken for 1 to 6 months
• December 13, 2019

"I went to the ER twice for a migraine and received Compazine, Toradol, and Benadryl via IV. Both times I felt like my body was not my own. I instantly felt jittery and couldn’t sit still. I wanted to jump out of my skin. All I wanted was to go home. The cocktail worked, but when I was finally released, I could barely drive home because I couldn’t sit still for more than a few seconds. I had to pull over multiple times. I called the ER when I got home because I couldn’t sleep at all. The nurse told me to take another dose of Benadryl and it should subside. It took 2 days to get back to normal. I thought it was the combination of Compazine, Toradol, and Benadryl that caused this side effect until I was admitted to Johns Hopkins for DHE treatment. They gave me Compazine before the start of the treatment, and I immediately felt crazy. All the symptoms I felt in the ER happened again. The worst medication I have ever received. Count yourself lucky if you didn’t experience this."

• Han...
• Taken for less than 1 month
• September 9, 2019

For Nausea/Vomiting "I went to ER for uncontrollable vomiting. I was given Compazine (don’t know the dose but was via IV push and a syringe full). Immediately, I felt anxious and panicky. When I asked the nurse if this was supposed to happen, she said if anything should make me feel more relaxed, WRONG! It’s been exactly six days, and I still feel overly anxious, strangest and most scary vivid dreams, and cannot sit still. Have to walk nearly 8 miles a day to barely be able to sleep at night. BELIEVE THE REVIEWS, I HOPE AND PRAY SOMEONE CAN SEE THESE AND PREVENT THE AWFUL SIDE EFFECTS OTHERS ARE EXPERIENCING! That is definitely going to be listed as an allergy to medication in the future. I would have much rather dealt with throwing up from food poisoning than deal with these endless awful feelings. If anyone knows when I will be feeling normal again and constant panic and anxiety will go, and the awful scary dreams would stop, please PLEASE let me know or post here, I will check regularly."

• Pik...
• January 24, 2019

For Anxiety "Went to the ER for extreme neck pain due to a strain. Was given Toradol and Compazine through IV, I reminded the nurse that I was allergic to Reglan and most likely this as well. She said she was going to give it a try for my headache. Big mistake. While getting ready for my head CT, the side effects hit. It was horrible. Extremely agitated, anxious, wanted to rip my IV out. Worst anxiety attack I’ve ever experienced. Went home and tried to sleep it off with no avail. I started hallucinating, and it wasn’t until I literally drank a huge amount of liquids to pee it out that I found relief. Never again. It’s the day after, and I’m still not 100% me. Don’t take this!"

• Ema...
• November 19, 2019

For Anxiety "Like many on here, I too went to the ER for a severe migraine. I have been given Phenergan and Toradol, and that always does the trick, but this time I went to a different hospital, and they gave me Compazine and Benadryl. Within seconds, I felt anxious. I wanted to rip my IV out, and I felt severely claustrophobic. One of the worst experiences of my life. I would have rather kept the migraine than go through that again. When I got home, I still had anxiety, and it didn’t completely go away for a day or two. I’m still scared to go to a hospital after this experience, and I’m actually scared of IVs now."

• saa...
• February 21, 2016

For Nausea/Vomiting "Went to the ER twice with a severe migraine, both times given Compazine. It definitely helps with relieving the pain, but the side effects outweigh it for me. Felt like my skin was crawling, restlessness, skin rash, dry mouth, anxiety (triggered a panic attack both times), brought up a lot of bad thoughts of how I was dying. Long term, rebound headache, insomnia, loss of appetite. Also had it with Benadryl once, and that scared me."

• Anonymous
• March 7, 2010

For Nausea/Vomiting "I experienced the 'restless, anxious' side effects from this medication, and it's been almost 24 hours, and I am still feeling it in my legs. My headache is gone, which is great, but my legs can't stop moving."

• Anonymous
• August 15, 2018

For Nausea/Vomiting "I was given this for nausea and a migraine. It did not help me with either, but made me anxious, and I felt like my skin was crawling. I've never experienced anything like that. I was ready to pull the IV out myself and escape from the room if they didn't hurry up and discharge me. I've never had a response to a medicine like that before, and it was absolutely awful. Worst hour of my life."

• Ano...
• January 31, 2017

For Nausea/Vomiting "This is the only medication I have ever been given in my entire life that has made me literally want to rip out my IV and run out of the ER. I was given this in the ER to curb the side effects of my lumbar puncture. I have anxiety and RLS, so in the beginning, I thought I was just experiencing a minor panic attack. I felt so restless that I had to go to the bathroom just to do something with myself. When I got back to the bed, I immediately told my gf that I wanted to leave. Was pushing the call light. And damn near left screaming. I flipped my shot on the doctor, and he said this was a common side effect. I told him I feel like I'm going to have a panic attack, and he gave me Benadryl and some kind of benzo. Absolutely horrid."

• Kon...
• Taken for less than 1 month
• November 15, 2019

For Nausea/Vomiting "I went to the ER yesterday for a migraine and was given Compazine and fell asleep, however, when I woke up, I felt off, like something wasn't right. I couldn't stay still, I just felt uneasy. It wasn't until I read the comments in this thread that I realized that the Compazine had a side effect on me. I will definitely put it on my non-medication list. I still feel weird the next day. I even called off of work. I hope this helps someone else."

• ano...
• November 29, 2018

For Nausea/Vomiting "My mother had a colonoscopy and had a vocal chord spasm, which caused her to cough during it. They gave her some medicine (I don't remember the name) to help dry up her secretions and calm down the coughing. This made her chest tight, painful, and made her feel nauseous after she got home. I took her to the ER, she is allergic to Reglan, so they gave her a mix of Benadryl and Compazine for nausea. Within 5 minutes, she was jittering around and felt like she wanted to rip her IVs out and run home. Her anxiety skyrocketed and her heart rate went up to 154 bpm. It wasn't until they gave her Ativan that her heart rate went down and she was able to calm down. We got sent home, and she was still anxious and fidgeting around for about 4 hours until she finally fell asleep. She woke up and still felt a little anxious and fidgety, but not near as bad as last night. One of the worst experiences she and I have ever had, and she is going to have it noted that she is allergic so she never has to go through it again."

• EAa...
• Taken for less than 1 month
• August 16, 2019

For Nausea/Vomiting "I've never experienced anxiety, I don't take any medication for anxiety, but thanks to this drug, I had my first panic attack. I went to the ER for extreme nausea due to painkillers given to me to alleviate the pain of some kidney stones. Right after being given this medication, I started feeling jittery and like I couldn't breathe. Ten minutes later, I wanted to rip out my own IV, my entire body was shaking and was having facial contractions. The doctor laughed it off, saying I was being overly dramatic and I just needed to breathe. It was the worst experience I've ever had, and I thought the kidney stones were bad enough. Three days later, and I'm finally starting to feel like myself again. I will never take this drug again and have no idea why it's still on the market."

• EAa...
• Taken for less than 1 month
• August 16, 2019

For Nausea/Vomiting "I've never experienced anxiety, I don't take any medication for anxiety, but thanks to this drug, I had my first panic attack. I went to the ER for extreme nausea due to painkillers given to me to alleviate the pain of some kidney stones. Right after being given this medication, I started feeling jittery and like I couldn't breathe. Ten minutes later, I wanted to rip out my own IV, my entire body was shaking and was having facial contractions. The doctor laughed it off, saying I was being overly dramatic and I just needed to breathe. It was the worst experience I've ever had, and I thought the kidney stones were bad enough. Three days later, and I'm finally starting to feel like myself again. I will never take this drug again and have no idea why it's still on the market."

• Mad...
• February 10, 2018

For Nausea/Vomiting "I went to the ER with a migraine, and I got this through an IV. I was totally fine and all happy until this drug hit me. I went completely insane. I got claustrophobic, I wanted to kill myself, I started twitching, and I got super anxious. They gave me some Benadryl, which helped, so they sent me home. On the way home, it happened again, and it kept happening all night, even after I kept taking Benadryl. The only time I felt not insane was when I was sleeping, but I was still having weird dreams. The next morning, I woke up, and I was still really anxious, but the serious side effects went away. For 2 more days, I still felt anxious, and it was the worst thing ever. Everyone told me this was really rare, and I don't think any of the people there at the ER really knew what was going on. This is a scary drug. I just wanted to share my story."

• Rut...
• Taken for less than 1 month
• November 29, 2018

"I went to the ER for a migraine and was given this medication combined with Benadryl. It basically induced a panic attack, and I felt as if I couldn't breathe properly. It was awful, especially as I wasn't anxious about being in the ER, but after taking Compazine, I just wanted to leave."

• Sha...
• November 6, 2019

For Nausea/Vomiting "This was, like many others on here have said, a terrifying ER experience. I was given Compazine for what they thought was a migraine, plus Benadryl because they warned me about the anxiety. Upon giving it to me via IV, I felt a wave of panic enter my body. My heart stopped for a moment. I immediately wanted to get out of the hospital and tried to rip my IV out. I thought that would be the end of it. But it wasn't. I had crippling anxiety over the next 5 days! Yes, FIVE days. I had constant panic attacks where I would have to stop driving and pull over. One time I almost fainted during a meeting and had to go to the clinic. This drug made me dizzy, lightheaded, feeling like I was going to pass out all the time, gave me the strangest head pressure/tingling feeling, heart racing constantly. I will never ever take this drug again. Worst experience."

• Usl...
• April 6, 2019

For Nausea/Vomiting "I was given a migraine cocktail that had Compazine included in it. This medication made my symptoms a million times worse! I started with my heart pounding and a severe anxious feeling immediately. I was given this med through an IV. It literally felt like an instant panic attack. It's been 4 days now, and I still am having spontaneous bouts of anxiety due to this medication. The half-life is 24 hours with this med, and it's been well over 96 hours since I was administered it, and I'm still experiencing side effects. I also got low blood pressure, which gave me cold sweats, disorientation, and I was freezing. My only relief was from hot baths, which made my blood pressure go up some. I also had dissociation, as if I wasn't even myself, from this medication. I cannot stress enough how awful this medication is, and it should NOT be used as nausea relief unless it's for EXTREME circumstances. This medication is used in people with schizophrenia! I am still not myself days after, and it's miserable."

• NE6...
• Taken for less than 1 month
• February 1, 2019

For Nausea/Vomiting "I had experienced high agitation and restlessness with this drug before, so it’s been on my allergy list. Unfortunately, I was going through a difficult procedure, and it’s the only anti-emetic this office offered. It had been over 10 years since I took it, so I figured I’d try it again. Bad idea. This drug causes severe anxiety, agitation, muscle pain, and a general feeling of needing to rip out of your skin! I remember now why it was on my DO NOT USE list, the effects stay with you for a long time too. I will never take this again. There’s a reason it’s listed as a mental health drug/antipsychotic. In my opinion, it MAKES you psychotic."

• NE6...
• Taken for less than 1 month
• February 1, 2019

For Nausea/Vomiting "I had experienced high agitation and restlessness with this drug before, so it’s been on my allergy list. Unfortunately, I was going through a difficult procedure, and it’s the only anti-emetic this office offered. It had been over 10 years since I took it, so I figured I’d try it again. Bad idea. This drug causes severe anxiety, agitation, muscle pain, and a general feeling of needing to rip out of your skin! I remember now why it was on my DO NOT USE list, the effects stay with you for a long time too. I will never take this again. There’s a reason it’s listed as a mental health drug/antipsychotic. In my opinion, it MAKES you psychotic."

• Bab...
• Taken for less than 1 month
• October 22, 2018

For Nausea/Vomiting "I'm just getting this medicine for a headache cocktail. And let me tell you, I wanted to jump out of my own skin. I have never felt anything like it, it was absolutely horrible. Do not let them give you this medicine, especially if you have anxiety, which I have, and they knew that because I told them. Absolutely horrible, like your legs have bugs all in them, and they're just crawling everywhere. Never, ever again!!!!"

• Smo...
• Taken for less than 1 month
• July 4, 2021

For Nausea/Vomiting "I was given Compazine along with Tramadol via IV at the ER to help treat a bad migraine. As soon as they put it in my IV, I wanted to rip it out and leave. My mom was with me, and I stayed a few more hours until my bloodwork came back. I finally got discharged and just wanted to go home and sleep, but of course I couldn’t. I was jittery and shaky. I was pacing back and forth in my room. I couldn’t sit still. I can’t find the words to describe exactly what I felt, but I basically felt so uncomfortable and like I was going insane at the same time. I went back, and they gave me Benadryl, which did absolutely nothing. Luckily my mom had some leftover Lorazepam, which finally gave me some relief and allowed me to sleep. It took 2 days for the worst of it to wear off, but now, 6 days later, I still don’t feel 100% back to normal yet. I will never take this medication ever again, and I hope it gets taken off the market soon. I hope no one else ever has to experience what I did."

• Dra...
• Taken for less than 1 month
• November 5, 2022

For Nausea/Vomiting "Was given this drug in the ER for a migraine and nausea, they didn’t tell me what they were given, and I had the worst headache and didn’t even ask. Lo and behold, this medicine ruined my life after one dose!!! Was given with Benadryl, and I felt extremely anxious, panicky, my legs and body were so restless I thought I was gonna die on the CT table. I couldn’t put words together. It’s been 5 days, and I’m still not the same: panic attacks galore, anxiety, tight band around head/headache, fear of doom, and dizziness galore. This should be illegal."

• Kat...
• Taken for 1 to 2 years
• November 8, 2022

For Psychosis "First and last time I ever received IV Compazine. Within minutes of hitting my veins, I was severely anxious, like an acute psychosis. I jumped up from the bed and said, 'I gotta get out of here, I gotta go.' My husband was like, 'What the hell did they just put in your IV?' He called the RN in, and he gave me IV Benadryl, which did not help me. For the next 3 days, I was out of my mind, could not function, and honestly was scared to be alone for fear I may have hurt myself! My husband stayed home to care for me and make sure I did not hurt myself or take off running. Oral Benadryl and oral Ativan--nothing took the feeling away. Absolutely awful! I have never in my life had feelings of hurting myself or dealt with any mental health issues, it was completely terrifying! I don't understand why this medication is still on the market honestly!"

• Bri...
• June 11, 2018

For Nausea/Vomiting "I am nine weeks pregnant, and I went into the hospital last night with severe nausea and vomiting. I hadn’t eaten anything for almost 3 days and was down 5 pounds. I was having a migraine from dehydration, and they gave me IV Compazine, and within four minutes, I was feeling like I wanted to step out of my own body. I had severe anxiety, I felt like I wanted to rip out my IV and run home as fast as I could. I had this overwhelming sense of being so unbelievably uncomfortable that I couldn’t close my eyes because I was so panicky and so shaky, so uncomfortable I wouldn’t wish this on my worst enemy. I will absolutely never take this medication again. It’s been almost 24 hours since that medication was given to me, and I’m just now starting to feel back to my old self again. Needless to say, I’m on Zofran now for my nausea, and you couldn’t pay me to take Compazine again."

• Exp...
• Taken for less than 1 month
• October 20, 2019

For Nausea/Vomiting "Worse experience ever. I had been experiencing morning sickness and vomiting while pregnant and had gone to the ER. I had been given Compazine through an IV along with some fluids. Within a short amount of time, I felt awful, a tremendous amount of anxiety came over me where I could not relax or even think to the point of functioning. Felt like jumping out of my body. There must be some legal consequences and responsibility behind this medication and what it has caused. No one should have to go through this, nor do I think it’s safe for anyone, especially while pregnant."