Compazine for Nausea/Vomiting User Reviews (Page 5)

• Jennna
• May 9, 2016

"I was given this through an IV in the ER. I had terrible nausea and Zofran didn't touch it. Even though compazine did take my nausea away, it left me incredibly groggy yet restless. I spent the entire rest of the day in a haze. I've never abused drugs but I would imagine this is how you would feel when coming off of some sort of high yet it lasts all day long. I kept feeling angry and anxious as well. I would much rather have nausea and will never take this medicine again!"

• Migra...
• Taken for less than 1 month
• July 30, 2019

"This drug made me feel worse than any drug I ever received. I had a migraine and at the A&E. It was pure mortal terror from the minute they went into my vein. I had them stop the infusion immediately but it was too late. My heart rate shot up, and I felt like I was going to die right there on the bed. Sleep came on and off, but not because of being relaxed. More like passing out repeatedly. I slept for 24 hours and still feel pretty horrible the next day."

• bulldog
• Taken for less than 1 month
• June 18, 2019

"I suffer from severe headaches on occasion and usually Excedrin will do the trick. I had a headache several months ago that was there for 3 days. I finally broke down and went to the ER. They gave me Compazine and put me in a waiting room. Within five minutes I felt terrified like I had to get away. I told my wife to tell them to get my IV off me or I would rip it out of my arm. They let me sign-out AMA and I fled the hospital. For several hours after I felt like the walls were closing in and doom was imminent. I hate this medication and will NEVER take it again. Beware!!!"

• Meeka
• Taken for less than 1 month
• June 6, 2022

"I was given this drug in the ER for nausea and a bad headache. The nurse gave me this drug but said it was a Benadryl "cocktail". Immediately when I felt it pushed through the IV, my skin began to burn and I started to have a choking sensation. Honest to goodness, I felt like I was going to die. I started to have the worst panic attack of my life. The heart monitor I was hooked up to started beeping like crazy and my blood pressure shot through the roof. I was so scared because I drove myself to the ER. I felt like I was losing my freaking mind on this drug. The only thing the doctor on call said to me was "well, I guess you are allergic to Compazine". I was like, YOU THINK!!!!!! The next day, they let me drive myself home....To this day, I have no memory of I how I made it home but so thankful I made it safely. Word of caution, please be careful if you are ever given this drug. I feel like I have PTSD from that terrible night in the ER because of it. It's a HORRIBLE drug."

• Bear
• August 9, 2019

"My doc gave me this medication over 20 years ago for nausea. I ended up having an allergic reaction. I had anxiety and I couldn’t relax all day. I went to hospital because of dystonia. Awful day. It also induced OCD which I have been dealing with ever since. Has this terrible medication triggered OCD in others?"

• Lovin...
• Taken for less than 1 month
• April 10, 2019

"I was fine the first 24 hours after my benadryl and compazine injection for a severe migraine but now 3 days later I've been experiencing severe dystonia in my neck, back and right arm. My hand was clenched in a tight fist all day and I couldn't move it. Not only that but Compzine made me hallucinate. I was hearing and seeing things and thinking very negative thoughts. Never ever will I take this medication again."

• Hunni...
• May 1, 2016

"I was given this medication to help with the side effects of Chemo and radiation and it was ok the first day but as the days went on I began to feel irritated groggy and EXTREMELY restless but I was really tired like super tired. It kept me so drained that I slept for 22 hours! Almost all the side effects mentioned above (or below) I experienced them too. I will NEVER take this again! I rather be nauseous!!"

• Ktano
• Taken for less than 1 month
• August 6, 2019

"Normally I am given Nubaine. However, this time a younger ER Dr. Was hopping on the "no opioid" bandwagon. Everything seemed fine, then all of a sudden I wanted to rip out the IV. Benadryl made it better, but I now seem to be prone towards panic attacks in closed rooms. I never had this before. Are opioids worse than this?? No!"

• Anonymous
• Taken for less than 1 month
• June 26, 2023

"i went to the doctor with a headache and was given this medicine through IV, and it the was the worst day of my life. I literally thought I was about to die. It's been 5 days, and still don't feel all the way normal. The only thing is helping is Ativan."

• Cyster
• Taken for less than 1 month
• September 24, 2019

"I have Cystic Fibrosis so I am constantly in and out of the hospital and have been through various drugs through my life. I struggle with severe anxiety and panic attacks and OCD. I was admitted for routine IV antibiotics and the meds made me extremely nauseous. I was given zofran and that didn't help so they decided to give me Compazine. The nurse injected this drug into my port and the effects were instant. I felt anxious jumpy and thought I was going crazy. My room was so small which made it worse and I was pacing around ready to pass out. I thought I was going to have to be admitted into the pysch ward. I rang my nurse and let her know what was happening and she had me lay down my legs started shaking uncontrollably. She got the doctor and that's where my legs started locking in place and I couldn't move them. They pumped me full of Benadryl and Ativan to calm me down. It took a good 24 hours to feel relief, this induced severe ptsd from this experience."

• MrsMack
• Taken for less than 1 month
• November 15, 2018

"Had this for nausea, the reaction to it was delayed so it took a long time to figure out what was causing the violent reactions, I was finally told it was all psychosomatic aka all in my head ! Would get muscle spasms started in the left arm then traveled to my face and jaw, if I could catch it fast enough I could put a towel between my teeth but did thousands of dollars of damage with breaking off teeth !! After it subsided my whole face looked crooked and my jaw did not line up right for days. Highly dangerous stuff."

• Anonymous
• September 26, 2019

"I was given this Compazine last night for a migraine. I knew I shouldn’t of taken it because I’ve had a bad experience with reglan. The doctor assured me that it was far less likely to happen and I even asked the nurse to push it in slowly. It took a few mins to kick in but once it did I knew the feeling all too well. Extreme anxiety and just an uncontrollable feeling of panic. You want to move around because you can’t think and you want to escape but then you’re afraid to move. They offered to give me Benadryl but I was just afraid at that point. It eventually mellowed out slightly and they discharged me. I went home and had a issue sleeping because I couldn’t sit still or stay asleep long. Next day it’s been a little over 12 hours and I still feel restless and so tired. I’ve tried to sleep but I feel like I have to keep moving. I wasn’t even able to go to work. I would have preferred having my migraine. ONLY GET TORODAL AND ZOFRAN OR BENADRYL for your migraines."

• Nuge
• July 10, 2019

"I was on this thread a while ago to see if people had a similar experience and I’m just now deciding to post because I remember how horrible it was. I went into the ER with pancreatitis and instead of promethazine they decided to do compazine...I wish I could go back in time and stop the nurse from administering it. They pushed it with IV dilaudid so it took a bit for me to feel the negative effects but long story short...crippling anxiety, sweats, uncontrolled movement (dystonia), insomnia, the list goes on. Didn’t sleep for 56 hours and the only thing that even helped a little was walking...I walked that entire time. This medication is the worst"

• Plain...
• October 26, 2010

"I have been suffering with gastroparesis for years, and at one point ended up in the emergency room because I was so intensely nauseated and dehydrated. Was given Compazine in IV solution, which worked wonderfully to stop the nausea. The doctor sent me home with Compazine pills, and they weren't as effective."

• Anonymous
• August 17, 2018

"When to the ER for migraine and Lyme Disease joint pain. I was given Compazine and immediately had a dystonic reaction!! My whole jaw locked up and my body was twitching and restless legs. The Dr ordered Benadryl stat and eventually the symptoms slowed down. They kept me overnight due to the reaction I had. I will never ever have this drug again. Everywhere I go I say I’m highly allergic to Compazine (prochlorperazine). Be careful with this drug."

• Fred
• Taken for less than 1 month
• October 21, 2019

"Absolutely worst ER experience in my life. If you are familiar with Benadryl this is a similar but much worse feeling that's lasts longer. I'd take migraine pain any day over relief from this awful drug. It didn't work anyway. I also felt like I wanted to crawl out of my skin and rip the IV out. I remember the feeling coming over me and thinking to myself "no, no, nooooo" A day later I'm still not myself. Avoid at all costs, ask for toradol if the doc isn't opioid friendly."

• Pseud...
• Taken for less than 1 month
• December 21, 2017

"Look up "dystonic reaction" before taking this med and be prepared to go to the ER if your muscles start freezing up. Taking this med led to one of the scariest experiences of my life. It definitely worked for the nausea, but at the cost of becoming a squawking, paralyzed contortionist. I must have looked like I needed an exorcism by the time I arrived at the ER, but only took an ambulance ride and several IV shots of both benzatropine and Valium to get me back to normal."

• Marie
• October 22, 2019

"I went to the ER and I told them compazine would make my skin crawl. The dr didn’t believe me and had it put in my IV It was 100 time worse in an IV If my husband hadn’t been there I would have ripped the out Ran and got the nurse and they said well we didn’t think it would do that. You have to just let it run it’s course now There is nothing we can do to fix it"

• Shani
• September 5, 2020

"I was given the migraine cocktail (benadryl, compazine, toradol) in the ER after suffering off and on for weeks from headaches. After my MRI came back clear is when they gave me this thru IV. I felt like I was going to jump right out of my skin, it was awful. I'm lucky that this feeling lasted only 15mins, it worked but to me, that anxiety it caused is not worth it! If I have to ever be seen for that again, I will be steering clear of that mixture!"

• DDano
• Taken for less than 1 month
• June 15, 2018

"I was given compazine for extreme vomiting and it literally made me have an out of body experience. I could see my body in the hospital bed but it felt like I was getting up and waking away from the bed so I kept holding on to the railing of the bed. It was horrible. I felt like I was two people and I had no control over my body. I would never take this medicine again."

• Nomor...
• Taken for less than 1 month
• October 9, 2019

"Just like all the others. I was given this plus benadryl in the ER to treat headache+nausea. I soon wanted to claw out the IV, and I had this horrible sense of dread like I was going to die. I couldn't think of anything but wanting to get out of that room. After getting home I was terrified to be alone. Finally slept it off mostly after several hours. Still feel off and jumpy 12 hours later. Never taking this medication ever again."

• Emmie
• Taken for less than 1 month
• June 16, 2019

"Refuse this medication. Went in with worst headache of my life, confusion and heavy, wave like sensation in my body. Was given Compazine and Benadryl through IV, was told I’d have anxiety. I have Generalized Anxiety Disorder and Pharmacophobia, so that in itself was irresponsible, I think. Instant panic attack, feeling of being on the edge of blacking out, constant, horrible anxiety, the wave like sensation, mood changes and Akathisia for the past month since being treated with this medication ONCE."

• Breezer
• Taken for less than 1 month
• April 27, 2021

"I went to the ER for a severe atypical migraine. They gave me Compazine via my IV along with Benadryl to prevent a side effect. After receiving it I have never been so restless in my life. I couldn’t stop moving and squirming. My husband thought I was going mad. It did help when they gave me additional Benadryl but I still couldn’t sit still or sleep. I felt like ripping my IV out. It was like I was a fish out of water flipping around. I had to get an MRI and I wasn’t able to sit still for that so they did give me Ativan which eventually helped some more by knocking me out, but I still felt uneasy before it put me to sleep and when I woke up as well. It’s now been two days almost 3, and I’m still feeling like I can’t relax or sit still which is making it hard to sit at work. I will never take this again and am having it added to my chart as an adverse/allergic reaction"

• Mom
• Taken for less than 1 month
• March 13, 2019

"Given Compazine with benadryl and wow the compazine caused a bad reaction!!! Felt like a 100+ worst nightmare from anxiety!!! Nurse seemed uncaring and didn't know this causes those side effects!!! This will go on my med list and I will stick with my zofran. Still feel bad some 12+ hours later. Never again. I can relate to the others!!!@"

• Sky
• Taken for less than 1 month
• February 8, 2019

"This did take away my nausea, but it also made my heart pound and made me extremely irritable and anxious for about 20 hours. Even with a Benadryl I couldn’t sit still for about 10 hours after taking it, and I had lingering anxiety 10 hours after that. I had a similar experience with Reglan, and the ER doc I saw said they are similar drugs. I would say if Reglan gives you a reaction there’s a good chance this will too. It did it’s job, but I would have taken the nausea over the anxiety any day."