Compazine for Nausea/Vomiting User Reviews (Page 3)

• Dra...
• Taken for less than 1 month
• November 5, 2022

"Was given this drug in the ER for a migraine and nausea, they didn’t tell me what they were given, and I had the worst headache and didn’t even ask. Lo and behold, this medicine ruined my life after one dose!!! Was given with Benadryl, and I felt extremely anxious, panicky, my legs and body were so restless I thought I was gonna die on the CT table. I couldn’t put words together. It’s been 5 days, and I’m still not the same: panic attacks galore, anxiety, tight band around head/headache, fear of doom, and dizziness galore. This should be illegal."

• Dam...
• January 2, 2019

"Went to the ER for a severe migraine... They gave me Compazine and Benadryl. 20 min later I was in a severe panic... ripping my IVs out. Calling out to the nurse, saying I was leaving!! They had to give me more Benadryl to reverse it. I left the hospital feeling worse than I did when I went in!! Horrible experience!"

• Mee...
• March 30, 2014

"I have been dealing with chronic nausea/vomiting for almost a year. I have had every test in the book, and they all come back negative. I've tried medications for irritable bowel syndrome, and I've tried Phenergan and Zofran, none of which worked. I also used the transdermal Scopolamine patch, which helped a little. Finally, my doctor prescribed Compazine suppository, and I have had great relief of my nausea/vomiting. I hope to be able to stay on this for a long time. It is a wonder medicine."

• Bab...
• Taken for less than 1 month
• October 22, 2018

"I'm just getting this medicine for a headache cocktail. And let me tell you, I wanted to jump out of my own skin. I have never felt anything like it, it was absolutely horrible. Do not let them give you this medicine, especially if you have anxiety, which I have, and they knew that because I told them. Absolutely horrible, like your legs have bugs all in them, and they're just crawling everywhere. Never, ever again!!!!"

• NoG...
• February 7, 2020

"I was given Demerol and Compazine to combat migraine and experienced severe agitation. The doctor recognized phenothiazine-induced akathisia and countered it with Benadryl and Ativan. Years later, I was again treated for HA. I double-checked the doctor knew I couldn't take Compazine. He ordered chlorpromazine and Valium. Unfamiliar with the generic, I didn't realize it was Thorazine (in the same class as Compazine). Another bad reaction. I pulled the IV out, fled, and paced at home for 15 hours. Surely, the doctor knew I'd react negatively. A couple years later, back to the ER for the first time since the Thorazine. I explained my reactions in detail. This time I was given Reglan. Again, I ripped out the IV and was headed for the door when the nurse caught me. Repeated doses of an antidote worked. I learned, subsequently, it's common to react badly to Reglan if you reacted to Compazine. Either the doctor was poorly informed or simply willing to risk my well-being. I've suffered at home in silence ever since."

• Exp...
• Taken for less than 1 month
• October 20, 2019

"Worse experience ever. I had been experiencing morning sickness and vomiting while pregnant and had gone to the ER. I had been given Compazine through an IV along with some fluids. Within a short amount of time, I felt awful, a tremendous amount of anxiety came over me where I could not relax or even think to the point of functioning. Felt like jumping out of my body. There must be some legal consequences and responsibility behind this medication and what it has caused. No one should have to go through this, nor do I think it’s safe for anyone, especially while pregnant."

• Me2...
• January 22, 2021

"I went to the doctor because of my dizziness and nausea. The doctor had prescribed Compazine to me for my nausea, which didn’t even work. Jump forward a few days, and I go to the ER to see if they can do something about it when I noticed I started having seizure-like attacks, where my body would stay in one position and my eyes would roll to the back of my head. The doctor said it was because I was allergic to the drug, even though I didn’t know. But isn’t Compazine supposed to no longer be sold?"

• Mea...
• Taken for less than 1 month
• July 27, 2018

"I went to the hospital due to a severe migraine and nausea. I was given Compazine via I.V. Oh dear! I immediately began having chattering teeth, severe anxiety, and uncontrollable clenching of teeth. I also could not remain still, as if I wanted to get out of there as fast as I could. I called the nurse in, and the response was, 'Oh, yeah, you feel kinda outta it?' Well, yes, it will pass, don't worry! ARE YOU SERIOUS RIGHT NOW! It's just by the grace of God that I got home safely. My teeth continued to chatter, and I could not sit still! I had to go back to the ER to get medicine to counter the side effects. I feel a little better now. Day 2 and still feel out of it. I WILL NEVER TAKE Compazine again!"

• Sil...
• Taken for less than 1 month
• December 15, 2017

"I was born with chronic pancreatitis and chronic migraines, so vomiting is a for sure thing every time I visit the ER. I have never in my life been traumatized by a medication until this encounter. It is like we are their lab rats, you feel helpless, insane, delusional, 51-50, a psychopath. You literally feel trapped inside your body, if that makes any sense. I try to hold my composure off this medication because it literally makes you crazy. It should be illegal for them to inject you with it without a warning on the side effects. You feel so weird for 3 days, it’s as if your innocence has been robbed from you, a form of violation."

• Bri...
• June 11, 2018

"I am nine weeks pregnant, and I went into the hospital last night with severe nausea and vomiting. I hadn’t eaten anything for almost 3 days and was down 5 pounds. I was having a migraine from dehydration, and they gave me IV Compazine, and within four minutes, I was feeling like I wanted to step out of my own body. I had severe anxiety, I felt like I wanted to rip out my IV and run home as fast as I could. I had this overwhelming sense of being so unbelievably uncomfortable that I couldn’t close my eyes because I was so panicky and so shaky, so uncomfortable I wouldn’t wish this on my worst enemy. I will absolutely never take this medication again. It’s been almost 24 hours since that medication was given to me, and I’m just now starting to feel back to my old self again. Needless to say, I’m on Zofran now for my nausea, and you couldn’t pay me to take Compazine again."

• Abb...
• November 15, 2017

"Was given Compazine for the first time in the ER. It was mixed in a cocktail for my headache. After 3 minutes, I started feeling uneasy, and I started to have a full panic attack. I’ve never felt that in my life! I ripped my IV out of my arm and started kicking the walls and stomping, they thought I was insane! I told them it was the medicine, they didn’t do anything, just released me, and I felt like my skin was crawling for 3 days. Was the absolute worst experience of my whole life!"

• Ren...
• October 30, 2015

"Had nausea from chemo and radiation and was given Zofran. Zofran did nothing to curb the nausea. I was just recently changed over to Compazine and the nausea is gone! I've not experienced any side effects whatsoever."

• Bea...
• Taken for less than 1 month
• June 27, 2019

"I wish I could give this drug 0/10 stars. This is not a drug that I would give to my worst enemy-and I have tried many drugs for migraines! I was given this with the migraine cocktail in the ER, which also includes Benadryl and Toradol. I experienced extreme anxiety and restlessness. I wanted to rip the IV out of my arm and run out of the hospital... not that I could have done this anyway because it caused me to have extrapyramidal and dystonic side effects! When I got discharged from the ER, this was the worst night of my life. My friend had to sleep over because I was freaking out. The side effects lasted for 2 days."

• Pat...
• Taken for less than 1 month
• May 16, 2019

"It is absolutely horrible. I went into the ER yesterday with a bad headache on one side. They wanted to give me some cocktail that included Compazine and Benadryl combined. I said no. I should have done my research on Compazine prior to getting it intravenously. The worst mistake of my life. I had shakes, anxiety, which I don't have, the worst dry mouth of my life, that I almost choked on my sugar pill. I felt like it had been out in the desert for a year. I could not keep my mouth moist fast enough. It has been almost 24 hours, and I'm still not back to 100 percent yet. That drug is toxic. I would never, I don't care how much pain I'm in, ever take that drug."

• Yva...
• June 24, 2019

"Worst medication! About 9 years ago, when I was in high school, I caught mono and was vomiting a few times when my mother took me to an ER/urgent care. They gave me an IV with Compazine and a prescription for home. It wasn't until maybe the second day I couldn't move my muscles. I had ZERO movement in my body and could barely walk or get dressed. Nothing. I constantly shook like I was having a seizure. I couldn't sleep for an entire week! Let alone sit still. It was constant anxiety. It's like I lost all ability to relax. It was a living hell. When I went back to the urgent care, the lady literally told me it was mono. I went home and continued to take this medication, not knowing I had a severe allergic reaction. Finally, I went back again and got a doctor who actually knew what was going on! He told me to stop taking Compazine ASAP. People get PERMANENT damage from this! It took over a month for this to leave my system, and until this day, the anxiety is still there."

• mom...
• Taken for less than 1 month
• October 31, 2022

"It has been a little over six months since I was given Compazine through my IV when I had a migraine, and I am still not right. It’s important to note that prior to the injection, I have never had any problems with mental health besides intermittent anxiety (mild). I went to the ER for a severe migraine that had been lasting a few days. I was given Compazine through my IV for the pain. I immediately had the worst panic attack of my life. I can’t even compare it to other panic attacks I’ve had because it was profoundly horrific. Wanting to escape, suicidal thoughts, terror, wanting to rip the IV out of my arm, and extreme restlessness. I have had debilitating anxiety ever since. After reading many of the reviews, I see most people feel better after a few days, but that hasn’t been the case for me. I have now been struggling with never feeling at peace or comfort. I can no longer feel love, happiness, joy, or even experience laughter. I walked out of that hospital a different person. Please avoid."

• Ass...
• Taken for less than 1 month
• December 28, 2014

"I was in the hospital suffering from post-lumbar puncture headache and nausea/severe vomiting. IV Zofran did nothing, IV Reglan did nothing, only the IV Compazine gave me relief. Granted, as soon as it ran out, I started up again, but at least it allowed me a few hours of peace to sleep."

• Yik...
• Taken for less than 1 month
• November 8, 2022

"Please don’t take this medication. They gave it to me through IV as a part of their useless “migraine cocktail,” which needs to be discontinued in and of itself. Needless to say, within 10 seconds, I was hot, sweaty, agitated - ready to pull the IV out, and I’ve had RLS before, this was a tad worse. The pure akathisia felt like hell. Then they gave me this as opposed to stronger meds because they were worried about me driving, but hell - if only they knew that this was more dangerous to drive with, maybe they would have reconsidered. This stuff makes you feel depersonalized, more sick, helplessly “under” (the best way I can put it), and the only way out is TIME. Benzos make it more tolerable (slightly). I’m on day two afterward, and I feel fortunate that I’m about 75 percent “back” from whatever hellish trip that was. It’s now on my allergy list. Lawsuit!"

• Han...
• May 19, 2016

"I took this for my extreme amount of nausea causing anxiety. It did wonders for my nausea! It was wonderful and like a miracle. Until the third time I took it... I had the worst experience of my life. My jaw got locked and stuck to one side, my eyes got locked looking upwards, and I couldn't move them. My jaw felt as if it was trying to break itself and was so painful. I ended up sticking my finger down my throat to make myself vomit up the drug. It continued to lock my jaw up off and on for the next 48 hours. Never again. Be careful of the side effects. Worked wonders for my nausea and vomiting, but I would rather be throwing up than experience those side effects."

• MDa...
• Taken for less than 1 month
• February 17, 2019

"I was in the ER due to a severe migraine that couldn’t be controlled with my prescriptions that I usually take. They gave me Compazine for the nausea/vomiting. It was the most awful thing ever. I became so restless. I felt like I had to leave and go home. I couldn’t sit still, and I felt like I constantly needed to pace the room. I felt like I was going crazy, and like I was about to rip my hair out. (I didn’t.) I will avoid this medicine at all costs. I don’t even know if it helped the nausea/vomiting because it made me feel so weird."

• Anonymous
• January 5, 2010

"This medication does help out a lot when you have nausea. I have taken a lot of different medications before, and this is the first one in seven years that has actually worked for me. The only side effect that I get from it is being tired after taking it, but it is so much better than being sick to my stomach."

• Ang...
• Taken for less than 1 month
• May 17, 2018

"I have been given Compazine in my IV, and it was one of the most horrible experiences of my life! It almost immediately made me very anxious, I wanted to pull my IV out and just get out of the hospital! I felt zombie-like, and my face went numb. I had side effects like these for about 3 days! Never again will I take Compazine!"

• Hor...
• Taken for less than 1 month
• September 18, 2016

"The absolute worst experience with an antiemetic I have ever had. I literally panicked in the hospital to the point I almost pulled my IV out. Zofran stopped working for my hyperemesis gravidarum, but I would rather live with nausea and vomiting day in and out than feel the uncontrolled anxiety and restlessness I felt with Compazine!"

• LCa...
• Taken for 6 months to 1 year
• August 20, 2020

"I was first given Compazine orally for anxiety and nausea. It did not appear to have any side effects. A year later, I was hospitalized following surgery and was extremely nauseous, so after giving me Zofran to no avail, they gave me Compazine IV. It burned going into my arm. I became very agitated and restless, my body could not stop shaking, and I felt like I was going to jump out of my skin. Luckily, they gave me Benadryl, and that helped calm me down a bit, but it took a couple of days to feel myself again. Will never take IV again."

• Zan...
• Taken for less than 1 month
• March 27, 2021

"Do NOT use Compazine!! I went to the ER for a severe migraine that lasted a week. They put me on Compazine, and within just a few minutes, I was shaking uncontrollably, couldn’t keep still, and had extreme anxiety, like if I didn’t leave the hospital RIGHT AWAY, my entire life would just go down the toilet. This was the only time I ever ripped out an IV. I called the nurse in, and I could only mumble “Oh God, what did you do to me” over and over again. After some of these other reviews, I count myself lucky that my symptoms only lasted a single night and the migraine did go away. But still, I will never take it again!"