Compazine for Nausea/Vomiting User Reviews (Page 4)

• Poo...
• Taken for less than 1 month
• March 23, 2019

"I went to the ER last night with nausea and vomiting. I was given Zofran, but it had soon worn off. I told the doctor, and he said he would give me something else. The nurse came in with the Compazine. She gave it to me through my IV. Within minutes, I started to feel really jittery and restless! I started to become anxious and fidgety, and I wanted to rip my IV out of my arm. The medicine worked for the nausea, but it's definitely not worth the side effects! It was the worst feeling ever!!! It has been 21 hours since, and I still don't feel right. The symptoms have calmed down a lot, but I'm still not 100%."

• Anonymous
• Taken for less than 1 month
• November 30, 2017

"I went to the ER with nausea, they gave me Compazine immediately. I felt hot and restless. I freaked out, they moved me from the hallway to a room where I became restless and angry. My jaw locked up, and I was shaking uncontrollably. My heart raced, and I felt like I was gonna die. My symptoms lessened after about 8 hours, where I slept off and on. I went to a different ER, and they gave me a small dose of Ativan, but it didn’t make me feel any better. The next day, I still feel panicky, and my heart feels weird, and the shaking comes and goes. I also have horrible diarrhea. Worst experience of my life."

• Kad...
• Taken for less than 1 month
• April 2, 2019

"I've had three OHS (open heart surgeries), so I've had my fair share of IV medicine. NOTHING, and I repeat, absolutely nothing I have taken has made me feel as awful as this did. Five minutes after receiving the dose of Compazine, I started getting restless, like I wanted to crawl out of my skin. I complained about how uncomfortable I truly was, and the doctor just said, 'Oh yeah, that happens.' Please don't take this, it may have helped my pain. But here I am, 19 hours later, still feeling like complete garbage. I honestly wish I would have read these reviews first."

• Anonymous
• Taken for 1 to 6 months
• August 3, 2015

"I was suffering from unexplained nausea for about a year. I tried a host of other anti-nausea medications, but nothing really seemed to be helping. My doctor gave me Compazine, which helped my nausea but made me exhausted by the evening and caused me to burst into tears at least once a day. I stopped taking the medication because the side effects were too much for me to handle."

• Mah...
• Taken for 10 years or more
• February 3, 2017

"I was talking to my sister about my bad reaction to a medication I took 15 years ago called Compazine. I took this prescribed medicine while at home. I remember my experience like it was yesterday. At first, I felt a twitching in my jaws. All at once, my bottom jaw started going to the right, and my top jaw started going to the left. I could not stop it, and I could not talk. In fact, my jaw felt like it was trying to break off my face. I remember the emotional and physical pain. My husband and I were both crying because we both didn't understand what was happening! My husband ended up taking me to another clinic, and they admitted me at once. So BEWARE! Just from talking - I found out this same medication hurt my sister just last year."

• dha...
• Taken for less than 1 month
• March 4, 2017

"I was given Compazine through the IV for nausea and vomiting while admitted. It was an absolute nightmare that still makes me feel pure fear when I think about it. I thought I was going to die. At first, my legs just felt restless, which I thought I was just having some anxiety, but then it really hit. I couldn't get my body to cool down, I started vomiting, then lost control of my bowels in front of the nurses. This lasted over six hours until they finally gave me something that knocked me out until it was over. I thought I was going to die. It scared both my partner, who was there, and myself to the point that I am now scared to take any more medications, fearing a similar reaction. They should really warn people about this drug."

• Cat...
• Taken for less than 1 month
• April 4, 2019

"I thought I had the flu, so I went to the ER to get tested. It came back negative, but since I had a migraine, they gave me a “headache cocktail” which my sister had a bad reaction to, but I had forgotten (after all, I had a migraine and couldn't think straight). I got the IV meds, and one of them was Compazine...the awful liquid itself. Immediately, I had trouble getting comfortable, and my throat felt like I had a shrunken airway, but the doctors said it was just anxiety. So, it’s 4 in the morning, and I’m stumbling around the hospital waiting for my prescription and my stepdad to come pick me up, and I’m falling asleep any time I sit down. As soon as I got home, I fell into bed and couldn’t sleep unless my legs were writhing around. Then I slept off and on for almost 20 hours. I sweated most of the medication out, thank goodness, but I’ve never had anything like it happen before. I was by myself and was terrified. Why is this medication even still given?!?"

• Ahr...
• Taken for less than 1 month
• October 31, 2016

"I had been suffering from severe nausea and vomiting on and off, including migraine, fever, and flank pain. It was my second time in the ER, so they gave me Compazine and I'd never had it, it relieved my nausea and migraine, but I started feeling so restless. I was freaking out, like I wanted to rip out my IV and leave and run away. Then they told me it's a side effect, and I already suffered from severe anxiety, it made it 1000x worse. I had the worst time trying to sleep, then had the weirdest dreams of my life. They gave me morphine shortly after, which calmed me a little and took the rest of my pain away, but I was hoping it'd honestly put me out. 24 hours later, and I still feel that restlessness in my body, but it's so much better than it was."

• SPh...
• May 28, 2016

"I went to the ER for stomach pains and nausea. I am allergic to so many pain medicines that there is little I can take. They gave me Compazine, and as they put it in my IV, they told me it could cause severe anxiety in some people. Well, I can tell you now, it was horrific. I have had one major panic attack in my life, and this was 20 times worse. I started pulling off my clothes and ripped the IV out. They had to give me a big dose of Benadryl to 'reverse' the effects. Please, please think twice and consider other choices before taking this!"

• Kat...
• June 23, 2020

"Took this for a migraine cycle, and while it helped with the migraine. When the nurse gave it to me, it made my heart race, and it made me have the worst panic attack. I couldn’t stay still because my legs were restless, and I was extremely hot and loopy. I won’t take this again."

• Ash...
• Taken for less than 1 month
• July 2, 2015

"I was given this for migraines. I was stationed in Hampton Roads, VA, doing my time in the Navy. I had a TBI in Bahrain and was sent to Virginia for various medical treatments. I had blackouts and severe migraines that made me see spots at least 3-5 times a week. It was pure hell, so I thought. I would try to tolerate it the best I could, and I began frequenting the hospital where I received this drug. It took some time to figure out which drug I was having the horrendous side effects from. Portsmouth Naval issued me a 'cocktail,' as they called it, with this drug included. Over a few experiences with various doctors, I figured out this drug was the culprit. This drug made me feel like something terrible was crawling under my skin. 6 hours of hell."

• Mig...
• Taken for less than 1 month
• July 30, 2019

"This drug made me feel worse than any drug I ever received. I had a migraine and was at the A&E. It was pure mortal terror from the minute they went into my vein. I had them stop the infusion immediately, but it was too late. My heart rate shot up, and I felt like I was going to die right there on the bed. Sleep came on and off, but not because of being relaxed. More like passing out repeatedly. I slept for 24 hours and still feel pretty horrible the next day."

• Ksw...
• Taken for less than 1 month
• July 21, 2019

"I was given this awful medication in a migraine cocktail. Within minutes, I was so anxious that I yanked my IV out and ran out of the hospital room. For hours, I couldn't stop moving my legs. It's been 3 days, and I'm still so anxious. I made the pharmacy write in notes that I was allergic to Compazine - prochlorperazine, so this never happens again."

• bul...
• Taken for less than 1 month
• June 18, 2019

"I suffer from severe headaches on occasion, and usually Excedrin will do the trick. I had a headache several months ago that was there for 3 days. I finally broke down and went to the ER. They gave me Compazine and put me in a waiting room. Within five minutes, I felt terrified, like I had to get away. I told my wife to tell them to get my IV off me, or I would rip it out of my arm. They let me sign out AMA, and I fled the hospital. For several hours after, I felt like the walls were closing in and doom was imminent. I hate this medication and will NEVER take it again. Beware!!!"

• Bea...
• August 9, 2019

"My doc gave me this medication over 20 years ago for nausea. I ended up having an allergic reaction. I had anxiety, and I couldn’t relax all day. I went to the hospital because of dystonia. Awful day. It also induced OCD, which I have been dealing with ever since. Has this terrible medication triggered OCD in others?"

• Mis...
• Taken for 6 months to 1 year
• February 18, 2019

"I was given Compazine for nausea and vomiting when I was having monthly (girls) problems, which almost always included throwing up with pain. Violent spasms, like tetany lockjaw. I did thousands of dollars of damage to my teeth, and my whole jaw was crooked for days after. But doctors all told me it was 'stress,' all in my head, not the meds. One time when I was in the hospital and they gave me Compazine by injection, it started within a few minutes, yup, it was the Compazine. Also, have to be careful with other meds that may contain it. I had Tigan, which worked pretty well, but is no longer made. Last time, the doctor gave me Zofran, but I had a tough time getting the insurance to approve it, as they wanted to give me the cheaper Compazine generics. Be very, very careful, as I have had a few pharmacists tell me some other meds were not related, only to find out that they were. Be sure to do your homework and double, triple check what is in what."

• Liv...
• Taken for less than 1 month
• March 21, 2019

"I went to the ER when I was experiencing headaches and vomiting due to a new medication I was put on. The doctors gave me Compazine, Toradol, and Benadryl through my IV. After a few minutes, I experienced the worst feelings of my life. I was thrown into a huge panic attack, I couldn't sit still, my heart rate rose to over 130. I had to stay in the hospital for 5 extra hours just to get my heart rate to return to normal. It took 24+ hours for the initial panic feeling to go away, and now going on 48 hours, my head still feels all foggy and I get dizzy when I stand up for long periods of time. I hope I return to normal soon, and I would not recommend this medication to anyone!!"

• Jen...
• May 9, 2016

"I was given this through an IV in the ER. I had terrible nausea, and Zofran didn't touch it. Even though Compazine did take my nausea away, it left me incredibly groggy yet restless. I spent the entire rest of the day in a haze. I've never abused drugs, but I would imagine this is how you would feel when coming off of some sort of high, yet it lasts all day long. I kept feeling angry and anxious as well. I would much rather have nausea and will never take this medicine again!"

• Bee...
• Taken for less than 1 month
• September 19, 2019

"If you are ever offered a sedative/nausea medication, please be aware that every single one of these recollections and experiences is true. I could compare almost exactly to each and every one of these stories. DO NOT TAKE COMPAZINE. It has been three days and I still do not feel normal."

• Thi...
• Taken for less than 1 month
• November 17, 2019

"I went to the ER for stomach issues as a teen, and I took it. Went home, and 45 minutes later my jaw shifted all the way to the left, and I couldn’t control it. My neck started leaning to the right. I was rushed to the hospital and given Benadryl through an IV. Lucky it worked, I was in so much pain."

• Sup...
• August 22, 2019

"I feel for all of you very much. All of those bad experiences, I also had. Plus, doctors and nurses don't seem to care, at least most don't. About 13 years ago, I went to the ER for nausea, vomiting, and diarrhea. I didn't feel well when I went in. As soon as they put Compazine in my IV, I felt terrible panic, restlessness, anxiety. I could not sit, lay down, or stay in one place for more than 5 minutes. I pulled my IV out and started running to my friend. I thought maybe I had a stroke. I didn't know. My friend tried to talk to the doctors. I was outside, I couldn't do anything to feel any better. I waited to die. I was afraid I would hurt someone. I was one of the top weightlifters in the world. I started banging my head as hard as I could on the concrete wall. Then I went back in the hospital bleeding. I thought then the doctors would do something to help me. They called the police, my friend got me home. I was worse. I took some Xanax. I still have anxiety from that experience."

• Nug...
• July 10, 2019

"I was on this thread a while ago to see if people had a similar experience, and I’m just now deciding to post because I remember how horrible it was. I went into the ER with pancreatitis, and instead of promethazine, they decided to do Compazine. I wish I could go back in time and stop the nurse from administering it. They pushed it with IV dilaudid, so it took a bit for me to feel the negative effects, but long story short: crippling anxiety, sweats, uncontrolled movement (dystonia), insomnia, the list goes on. Didn’t sleep for 56 hours, and the only thing that even helped a little was walking. I walked that entire time. This medication is the worst."

• 1au...
• September 29, 2017

"I took this during my first trimester of pregnancy for nausea. It worked wonders for about two days. On the third day, I started to feel strange at work and took a break. My forehead and throat felt like they were tightening. I decided to go home, and about halfway there, I felt my jaw forcing itself to the left while my top teeth forced to the right. I couldn’t control my face or tongue whatsoever. I should have gone to the emergency room, but instead, I decided to call it a day and try to fall asleep. I didn’t fall asleep until 2 a.m. or so when the flexes in my face finally subsided. The strangest experience of my life. My neck and jaw were so sore for days afterwards."

• Anonymous
• July 28, 2009

"I am an older adult in good health. I originally had dizziness (possibly from a virus or sinus bug), which caused nausea. This medication took away both symptoms within 1-2 hours, and I was able to carry on with my normal activities."

• Lov...
• Taken for less than 1 month
• April 10, 2019

"I was fine the first 24 hours after my Benadryl and Compazine injection for a severe migraine, but now, 3 days later, I've been experiencing severe dystonia in my neck, back, and right arm. My hand was clenched in a tight fist all day, and I couldn't move it. Not only that, but Compazine made me hallucinate. I was hearing and seeing things and thinking very negative thoughts. Never, ever will I take this medication again."