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Zofran and Constipation: What Users Say (Page 2)

Reviews for Zofran

Commonly mentioned side effects
  • Ale...
  • September 23, 2015

For Nausea/Vomiting "Sometimes have really terrible heartburn due to my birth control pills, and sometimes causes bad nausea. Wanted an alternative to promethazine. Works great for taming the nausea, but the side effects were pretty annoying. Terrible backache and constipation. Oh man. Won't be taking these unless I'm dying or something."

7 / 10
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  • Anonymous
  • June 22, 2009

For Nausea/Vomiting "I have been given this medication twice - once after surgery to deal with nausea/vomiting from the pain medicine and again for severe morning sickness from pregnancy. It has been very helpful, however, I have experienced severe constipation as a side effect."

9 / 10
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4 Report
  • Pre...
  • Taken for 1 to 6 months
  • April 17, 2025

For Nausea/Vomiting "After being diagnosed with hyperemesis gravidarum, I was given Zofran. The midwife suggested I waited until the 12-week mark as they don’t like to administer during the first trimester, so I had an alternative to then. I went from being sick multiple times a day to maybe once or twice a week and gradually to once every couple of weeks, etc. If I stop taking the medication, I will start to feel very nauseous again, which to me indicates I still need it (now 20 weeks). The only side effect I have is constipation, which could be down to pregnancy itself. I have had no other issues at all and am thankful to have this medication."

10 / 10
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Frequently asked questions

  • Ott...
  • Taken for less than 1 month
  • July 8, 2022

For Nausea/Vomiting "I was given this for nausea from gastritis. It really didn't help the nausea, but it did give me a headache, made me very tired, that I had to lay down, and then gave me short, awful nightmares that I woke from with something like an electrical shock. It also made my breathing shallow, and like many, the next day I was very constipated. It was not a pleasant experience all around. I find non-prescription products much better than this for nausea. This made me feel much worse, and I would never use it again."

2 / 10
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  • Med...
  • Taken for 2 to 5 years
  • June 29, 2013

For Nausea/Vomiting, Chemotherapy Induced "A cancer patient's best friend. I find it horribly constipating, so I always take it with a stool softener."

8 / 10
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23 Report

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  • Bab...
  • Taken for less than 1 month
  • March 16, 2021

For Nausea/Vomiting "I have been taking this for several days. It doesn't help my nausea or vomiting. It also is making me feel constipated."

1 / 10
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  • Anonymous
  • December 16, 2010

For Nausea/Vomiting "Caused severe constipation, but at least I could keep liquids and solids down. Had a headache when tapering off."

10 / 10
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  • Anonymous
  • February 23, 2009

For Nausea/Vomiting "Although this drug was very effective in curbing my 11-month-old son's vomiting and diarrhea, it caused him to have very hard stools."

6 / 10
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  • Anonymous
  • Taken for less than 1 month
  • April 12, 2022

For Nausea/Vomiting "I found it to work very well, however, I had headaches and constipation while using it, which personally I found to not make it worth it to take the medication."

6 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.