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Ondansetron User Reviews & Ratings (Page 5)

Ondansetron has an average rating of 7.8 out of 10 from a total of 503 reviews on Drugs.com. 73% of reviewers reported a positive experience, while 17% reported a negative experience.

Reviews for Ondansetron

Commonly mentioned side effects
  • A g...
  • Taken for 1 to 6 months
  • June 24, 2017

Ondansetron for Nausea/Vomiting "I've been on Zofran multiple times. For nausea and vomiting due to a digestive disorder I had, and when I was pregnant (24/7 sickness for most of the pregnancy). For the pregnancy, it was okay. It took the edge off. Nothing can ever truly 100% help that level of constant nausea, but it kept me from vomiting, so I was able to keep down water and food. For the digestive problem causing sickness, it was a miracle. Gives me a headache but well worth it. Going from feeling so sick to feeling way better. It works wonders."

10 / 10
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  • Gar...
  • Taken for less than 1 month
  • May 28, 2019

Ondansetron for Nausea/Vomiting "I like the Zofran pills when they actually work, but it seems like I have to take a pill, throw up, and then take another for it to be effective. Also, I always wake up with a headache once taken. I do want to note that when I was given Zofran in the hospital through the IV, I had no issues with nausea, it’s only when I take it orally that it does the opposite of what I’d like. All bodies are different, and this is just my reaction. I am on a low dose and have not upped the amount I’m taking. $45 for 15 pills (without insurance), and I’ve puked up half of them. Not worth it, especially when an anti-nausea causes nauseous."

3 / 10
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  • Anonymous
  • October 2, 2011

Ondansetron for Nausea/Vomiting "Zofran is a lifesaver! Works quickly and very well. I get bad anxiety and worry a lot, which causes recent and sometimes unbearable stomach upset. One pill and I'm good! I am so happy I found relief. It does cause constipation for me, but I'd much rather deal with that!"

8 / 10
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26 Report

Frequently asked questions

  • aaa...
  • Taken for 1 to 6 months
  • March 6, 2019

Ondansetron for Nausea/Vomiting "Zofran is incredible. I was prescribed it when I started suffering from constant nausea about three months ago, and it has been a lifesaver ever since. It works almost immediately, even after taking it for so long, and has only not worked twice, both times when I had already eaten fatty or greasy foods and had other meds in my system. It can make you extremely constipated, so make sure you're hydrating yourself and consuming lots of fiber, but other than that, I never experienced an adverse side effect or interaction."

10 / 10
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  • fio...
  • Taken for 1 to 6 months
  • January 16, 2014

For Nausea/Vomiting "Pregnant in 1994, I was the first person in Scotland to take this medicine, injected, and it saved my life and that of my unborn child, scared and feeling at a loss, it worked wonders. I was so thin, dangerously thin, dangerously ill, what a turnaround in the space of one week. The first thing I ate in 7 months came thanks to Zofran. I would recommend this to anyone who is suffering severe hyperemesis during pregnancy and not to worry, it worked out fine for me and my child, who is now 19 and has an amazing life thanks to ondansetron (Zofran)."

10 / 10
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  • Smi...
  • Taken for 1 to 6 months
  • May 24, 2020

For Nausea/Vomiting "I'm pregnant with my first. I was vomiting and couldn't keep anything down for the first 2 and a half months and lost nearly 13 kilograms in that time. I started taking the ondansetron 4 mg wafers (dissolvables) around the 2 and a half month mark, and they worked wonders. Within 5-10 minutes of taking one, I was feeling great and could conquer my day, but every now and again I take one, and I feel the same, if not worse. So they work great, but not all the time!"

6 / 10
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  • car...
  • February 2, 2008

Ondansetron for Nausea/Vomiting "My doctor prescribed this to me for pregnancy-induced nausea and vomiting. All of my pregnancies were horrible with nausea and vomiting. Well, this time I'm about seven weeks pregnant, and I have been taking the generic brand ondansetron orally dissolving tablets, they are small with a minty flavor. It melts quickly, and I must say I have not vomited one time this pregnancy. I have had mild tiredness, headache, dizziness, and much better than nausea and vomiting and being unable to eat."

9 / 10
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  • Bel...
  • January 31, 2016

Ondansetron for Gastroenteritis "I have to go into the hospital every two months because I start throwing up and go into a coma state if I do not get IV in me. They gave me Zofran the last time, and I was up and good as new in 5 minutes. I will keep this on hand at home for future episodes!"

10 / 10
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  • Eli...
  • Taken for less than 1 month
  • August 22, 2019

Ondansetron for Nausea/Vomiting "I have taken Zofran on and off for over 10 years. I have been given it after surgery for nausea and vomiting. Also, now again for gastroparesis. Sometimes the nausea and fullness in my stomach are very uncomfortable. Because there are little to no medications or non-invasive therapies, I sometimes will use this to help settle my stomach. While it does nothing for motility, it does alleviate rough times."

8 / 10
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  • Anonymous
  • May 26, 2008

Ondansetron for Nausea/Vomiting "This really is a lifesaver. I'm 17 weeks pregnant and have crippling morning sickness. So bad that I could not eat or drink anything for over a week. As soon as I took one pill, I became 100000000 times better. I would recommend this pill to anyone. I love it. 10 out of 10 in my book."

10 / 10
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  • Sav...
  • December 19, 2016

Ondansetron for Nausea/Vomiting "I had my gallbladder removed in September and have been on this drug (as needed) since. It is a godsend. I don't get as nauseated as I was the first month after surgery but still have nausea here and there. This drug works very quickly, and I feel instant relief. Sometimes I find myself needing to take 2 doses if the nausea is severe, and it helps to ease it. Recommend this for anyone that struggles with nausea."

10 / 10
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  • BFO...
  • December 8, 2016

Ondansetron for Gastroenteritis "Zofran is heaven-sent. It saved me and my baby's lives. I was sick for 9 months with hyperemesis gravidarum. I was on a Zofran pump as well as IV hydration. I don't know if my baby would have survived without it. I'm still using it for chronic nausea. I wish I could personally thank the creators of this drug. Thank you."

10 / 10
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  • Zof...
  • May 1, 2016

Ondansetron for Nausea/Vomiting, Chemotherapy Induced "I had a very long treatment time, 3X a week, 2 8-hour sessions with three types of chemo radiation. It was every 3rd week, Wed, Thur, and Fri. Wed/Thur were 8-hour sessions, Fri, 4 hours. I was constantly vomiting, morning, noon, and night. I took this from the get-go, but after about my 2nd session, I threw up a lot in the mornings, or if I coughed too hard even. I know it would have been SO much worse without the Zofran. I think with the amount of treatment I had, both chemo and radiation, to both my chest and to my brain that I was VERY lucky I wasn't more sick, and frankly, I'm lucky to be here at all. Thank you, Cancer Treatment Center, and of course, thank you, God!"

8 / 10
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  • Dee...
  • October 28, 2016

For Nausea/Vomiting "This is a wonder drug! As an emetophobe, norovirus season reasonably stresses me out. This med has worked wonders for me! Just a few days ago, my 3-year-old woke up projectile vomiting everywhere with a high fever. This mama panicked. He was so ill the pediatrician told me to take him to the ER. He was vomiting every 10 minutes at this point. They gave him a Zofran tablet, and he was better within 30 minutes, with a script for liquid Zofran to come home with. Of course, I feel ill as I have been exposed to the virus repeatedly. I took Zofran liquid this morning, and the nausea is gone! I am at work and no need to vomit. I am terrified of throwing up and will deal with the side effects if needed."

10 / 10
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  • Bri...
  • June 18, 2017

Ondansetron for Nausea/Vomiting "I have a variety of GI issues as well as a phobia of throwing up, and ever since I've been taking Zofran ODT, I've been able to function without throwing up in the middle of the night every night. My only complaint would be that after 5 years of taking it, it doesn't work as magically as it did at the start, but it still works wonders."

10 / 10
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  • Jac...
  • Taken for 1 to 6 months
  • June 18, 2019

For Nausea/Vomiting "I get awful hormone-related nausea every month at the beginning of my periods. It often (not always) happens at the same time as my menstrual cramps, and it keeps me up at night and prevents me from working during the day. Ondansetron/Zofran does what it’s supposed to, knocks out the nausea in about 30 min, with the only noticeable side effect being very slight drowsiness. The tiny pills are easy to swallow with a very small amount of water, good when almost everything is making you heave. Couldn’t ask for a better medication for this purpose."

10 / 10
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  • Mar...
  • April 30, 2016

Ondansetron for Nausea/Vomiting "I've been dealing with extreme nausea and vomiting for the past 6 months, and it finally got to the point where I couldn't take it anymore and went to the ER. They gave me Zofran through IV and was feeling better in about an hour. After I was released, I was on 4 mg every 8 hours, and for about a week, I was back to my old self. Then things started to go downhill, and they boosted it to 8 mg. Now it doesn't even work anymore and makes me more nauseous than I was before. I also got pretty bad constipation and headaches after taking the medication. Not to mention, if you're taking the tablets, be ready to handle the taste because it is DISGUSTING."

5 / 10
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  • nic...
  • October 22, 2014

For Nausea/Vomiting "I recently started Zofran 4 mg for constant nausea and vomiting due to anxiety and panic disorder, severe emetophobia, and gastritis, and have had great results. It does cause crippling stomach cramps at times and some constipation, but those I can handle. I forever thought of Phenergan as my miracle after taking it for 5 years for a failing gallbladder (it's removed now), but Zofran has been so much more effective at stopping the constant nausea and allowing me to eat normally again! I love and keep it with me at all times!"

9 / 10
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  • GCa...
  • Taken for 1 to 2 years
  • January 15, 2019

Ondansetron for Nausea/Vomiting "Since childhood, I’ve always been nausea-prone. Sometimes there would be a direct correlation, such as motion (car more often) sickness, overeating/unhealthy eating, etc. Mostly, it just comes out of nowhere and stops me in my tracks. Without insurance, it was very expensive (not sure how much, but $$$). Ever since having insurance and paying a few dollars, I will never be caught dead without a couple tabs on my person! My GI was very understanding and prescribed 60 tabs a month (up to 2 a day) with a generous amount of refills! Only once did it not work, but that was on New Year's, and I believe for obvious reasons! I’ve not really noticed side effects since my nausea throws off my body anyway. I take this med at least once a week. I can’t believe I wasn’t introduced to this sooner! It’s saved my life."

10 / 10
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  • Nor...
  • Taken for 1 to 6 months
  • April 3, 2018

Ondansetron for Nausea/Vomiting, Chemotherapy Induced "I'm one of those people that would rather be in pain than nauseous, so when I started chemotherapy, I knew I was in for a ride. I was given a cocktail of meds right before chemo and then Decadron and Zofran for a couple of days after for allergic reaction and nausea. For the times after that 'as needed,' I have Zofran & Compazine for nausea and Ativan for 'anticipatory nausea.' I guess the Ativan would help some commenters in this thread who actually get sick from thinking about getting sick. It made me too drowsy, so I was left with the Compazine and Zofran. I found the Zofran to be by far the most effective; I take one 4 mg tablet as soon as I start feeling queasy, and within 10-15 minutes, I am fine - I'm even able to eat. Thankfully, my insurance covers it as it is a little more expensive than some meds for nausea, but to me, it's worth not vomiting. I recommend this medication highly."

9 / 10
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  • Fiz...
  • December 13, 2014

Ondansetron for Nausea/Vomiting "I have been having a lot of stomach issues. I was told it was a bunch of things. At last, it took about 4 months to conclude it was my colon. After a bout in the hospital, I was given Zofran, which worked wonders in no time at all; was also given Phenergan at one point and immediately became extremely irate until I passed out from it. In comparison, Zofran is a godsend. Can be expensive."

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • August 20, 2012

Ondansetron for Nausea/Vomiting "Whole family in the hospital for stomach virus with severe nausea and vomiting every half hour. This medicine completely stops the nausea within minutes! It definitely gives you headaches and makes you sleepy, but this is a small price to pay to stop the nausea when you are in that situation."

10 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • October 21, 2012

Ondansetron for Nausea/Vomiting, Chemotherapy Induced "Overall, it has been the best antiemetic available for chemotherapy-induced nausea and vomiting. The downfall is gastric slowdown, which can become more pronounced if on vinca alkaloid chemo or opioids."

9 / 10
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  • Mar...
  • Taken for less than 1 month
  • October 30, 2013

For Nausea/Vomiting "I am 7 weeks pregnant, and around 6 weeks, the 'morning' sickness began. I missed 2 days of work because I was miserable. I finally decided to call my doctor because I did not want to be missing work, especially since no one knows yet. It works great! I can make it through the day at work without constantly feeling like I need to vomit. I still get stomach aches and a little constipation, not sure if it's related to the medicine, but I'd take that over the nausea and vomiting any day. It's a lifesaver for the workday!"

9 / 10
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  • Anonymous
  • Taken for less than 1 month
  • December 13, 2012

Ondansetron for Nausea/Vomiting "My daughter was experiencing a constant unexplained ache in her stomach and a feeling that she was going to throw up, that no stomach test could find. Three months later, an MRI showed she had an AVM in her brain. Surgery to repair took all symptoms away. Three years later, she started having the same feelings. Found out the feeling of throwing up was the aura before partial seizures they didn't know she was having. Still having the gnawing ache. One amazing doctor suggested Zofran... it was our miracle. She has been fine ever since."

10 / 10
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23 Report

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