Skip to main content

Systane for Dry Eye Disease User Reviews (Page 3)

Reviews for Systane

Commonly mentioned side effects
  • Jen...
  • Taken for less than 1 month
  • May 16, 2022

"Caused horrible migraines and nausea both times using drops, within 30-40 minutes of using 1 drop per eye. First time I did not think it was due to drops, second time, 2 days later, I realized the cause was the drops. Caused a migraine both times... not a headache, but full-on migraine!"

2 / 10
Was this helpful?YesNo
5 Report
  • Tom...
  • Taken for less than 1 month
  • February 7, 2022

"I have allergies, and my eyes get itchy, so I thought I would try Systane to soothe my irritated eyes. When I put a drop in each eye, my eyes became blurred over, and I could not see! As it dissipated some, I could not longer read the information on the box! It damaged my eyes! I flushed my eyes out three times with water, and it still didn’t help! They felt itchy and sticky. That evening, my right eye had a lump that appeared on my lower lid, which is still there! And my eyesight from the eye drops on Friday is still not back to normal! How can a company produce a product that is not safe to use? I am going to call my attorney!"

1 / 10
Was this helpful?YesNo
5 Report
  • Joh...
  • Taken for 10 years or more
  • August 30, 2022

"This has been my brand for the past 15 years, the product is very good. But the new bottle introduced in 2022 is not working well for me, the drop that forms at the tip most of the time is too big, like 3 drops in one. The product is wasted, it also doesn't fall always vertically in the line of the tip, so there is also wasted product. The former container was better."

4 / 10
Was this helpful?YesNo
4 Report

See also:

  • Ter...
  • Taken for 1 to 6 months
  • December 4, 2021

"Gave me swollen and puffy eyelids. I quit using Systane lid wipes and Systane complete drops as they made my eyelids puffy. Now I see that Drugs.com lists this as a side effect. Don't take a chance with your eyes. Costco may have to stop stocking this product."

1 / 10
Was this helpful?YesNo
4 Report
  • Ski...
  • Taken for less than 1 month
  • January 11, 2021

"I had some chemical go into my eyes on 18th December. The only symptom was some white discharge. I was put on Moxigram LX and Systane Ultra. Since 6th January, I have been seeing floaters and flashes. I went and got my eye retina checked and got to know that the vitreous fluid is sticking very tightly to the back of the eye, and I may get a retinal tear when it separates. I feel my vitreous fluid has changed its properties due to Systane Ultra, as I have started seeing flashes and floaters only recently (6th Jan). I may be wrong. I can't say. I have stopped Systane Ultra today. Will report back and tell you all if my symptoms stop."

1 / 10
Was this helpful?YesNo
4 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Anonymous
  • Taken for 1 to 6 months
  • March 25, 2022

"Started using Systane on the advice of an optometrist. It seemed to make my eyes burn, but I was under the impression that it was fairly benign medication. After a few months of using it periodically, it has become obvious to me that Systane has been the cause of my blurry vision and eye irritation. I woke up with some bad floaters and thought that it was the beginning of a retinal detachment. Kind of scary, and I don't know if it can be attributed to the use of Systane, but I can tell you that I will not use it anymore. You make your own decisions, but I would not advise its use."

1 / 10
Was this helpful?YesNo
3 Report
  • Ouc...
  • Taken for 1 to 6 months
  • July 24, 2021

"Have had dry eye for 15 years. Recently, my eye doctor provided a sample of Systane Complete. My eyes burn when the drops are applied. Continued stickiness in the eye. Redness of the eye. Would not recommend."

1 / 10
Was this helpful?YesNo
3 Report
  • sha...
  • Taken for 1 to 6 months
  • August 18, 2021

"I used Systane Relief for Dry Eyes about 5 years ago and felt my eyes got drier every day. The day I stopped was when both of my corneas tore when I woke up and opened my eyes due to my eyes being so dry. I saw my optometrist and contacted Systane. Systane quickly sent a courier to pick up their product and never reported anything back to me. I called them, and they wouldn't respond. 5 years later, I am having laser surgery to repair my cornea where I had the most damage and lost 1/2 of my vision in that eye."

1 / 10
Was this helpful?YesNo
5 Report
  • Beb...
  • Taken for 5 to 10 years
  • November 28, 2022

"I've used this wonderful product for years, but now I must change. The shape of the new bottle is awful. The product spills all over my face. What was a month's supply now only lasted 1/2 the time or less. I don't know if the design is to create waste so users must buy more, or if it's just a stupid design that I hope is corrected soon."

3 / 10
Was this helpful?YesNo
2 Report
  • Bur...
  • December 4, 2020

"I used Systane Ultra Drops, and I have been experiencing a painful ache in my eye ever since I put the drops in. Had used the gel before with no problem, so I am very surprised. Not happy with the product nor the response when I talked with Systane. Asked to have them send me the medical information containing the pharmacology, indications, and contraindications in detail. All they sent me was a copy of the back of the box."

1 / 10
Was this helpful?YesNo
4 Report
  • Ann...
  • Taken for 1 to 6 months
  • February 6, 2022

"After a period of Dr. appointments for red, sore eyes, I was given Systane. At first, I thought they were amazing but a bit sticky. Then, I wondered why my eyes felt like they were turning in or twitching. Today, I had to cancel my plans because it was like I had double vision. I realized it started about the same time as the drops and checked here. I must never use again!"

1 / 10
Was this helpful?YesNo
2 Report
  • Mar...
  • Taken for less than 1 month
  • July 30, 2021

"Glaucoma patient with a corneal graft who needs lubricant for dry eye. Was using Refresh ointment without incident. When I ran out, I was given Systane Original lubricant eye drops for use 4 times a day. After a few days, I developed SEVERE pain in my eye. My eye was BLOODshot, lid was swollen, I could barely open it to take my glaucoma drops. Stopped taking it right away. I also wasn’t told about preservative vs. preservative-free. I am hoping that when this nightmare is over, my vision will not be worse. I’ve already been through enough. Be forewarned."

1 / 10
Was this helpful?YesNo
2 Report
  • Bro...
  • Taken for less than 1 month
  • March 27, 2022

"My doctor prescribed Systane: 1 drop in each eye twice a day. I have used it for about 3 weeks. Lately, my eyelashes have been stuck together when I wake. This morning, I noticed they have become short and are almost gone. I am stopping Systane immediately. Forget Systane if you want your eyes to look nice."

1 / 10
Was this helpful?YesNo
2 Report
  • fel...
  • Taken for less than 1 month
  • August 29, 2022

"I used this for Fuchs' Corneal Dystrophy. I hope and pray this blurred vision goes away. I don't think my watery eyes in the morning problem will ever come back. This product has really dried up that problem."

1 / 10
Was this helpful?YesNo
1 Report
  • Ded...
  • Taken for less than 1 month
  • April 23, 2021

"I had LASIK about 4 years ago, and it left my eyes pretty dry. When they’re super dry, I notice my vision seems worse, so per my eye doctor, I use drops daily. I recently bought this Systane Gel, and I do NOT like it. The drops don’t feel as thick as Blink gel, but it leaves a film that doesn’t clear up, so it makes my vision worse. It takes almost 45 mins for my vision to get clear, which is unacceptable. Most of it seems to come right out and sit on my lashes. This was an expensive bottle, and I am pretty upset I wasted my money, I can’t use this anymore."

2 / 10
Was this helpful?YesNo
1 Report
  • Sys...
  • Taken for less than 1 month
  • September 5, 2021

"Love Ultra for my eyes, but tried Hydrate one. Both obscenely expensive, but they need to fire the people who thought that the new dropper style works. OMG, the most ineffective, stupid, waste-producing mode I have ever experienced."

1 / 10
Was this helpful?YesNo
1 Report
  • Mar...
  • Taken for less than 1 month
  • September 16, 2021

"After brief use for occasional dry eyes, I had extremely bad side effects. Tissue around my eyes red, swollen, itchy, burns. No relief since August. Working with doctors. It’s the preservative in this product. Shame on FDA approval for a bad preservative."

1 / 10
Was this helpful?YesNo
1 Report
  • Blo...
  • Taken for less than 1 month
  • August 1, 2022

"My doctor recommended these drops to cure my dry eyes. After about 5 or 6 hours (3 p.m. - 9 p.m.), I noticed a blood clot in my right eye, my dominant eye. I experienced blurred vision, also. I admit I put more than the two drops (maybe 3 or 4) per directions. But I've done the same with other eye drops as well and had no adverse side effects. I cannot recommend this brand to anyone, use with caution if you must!"

1 / 10
Was this helpful?YesNo
1 Report
  • Tul...
  • Taken for less than 1 month
  • August 4, 2021

"I started using Systane for dry eyes about 6 weeks ago. The last two weeks, I have not been using them as religiously, but 4/5 weeks ago, I started noticing a difference in vision in my right eye. Especially when light hits my eye when watching TV, etc. I have blurred vision in my right eye and cloudy streaks appearing. I am shocked and only connected the dots right now after looking at reviews online. I am really angry that these drops were prescribed. If any optometrist actually did some Googling, they would know these drops are dangerous to prescribe to their patients."

1 / 10
Was this helpful?YesNo
0 Report
  • not...
  • Taken for less than 1 month
  • October 1, 2021

"I used Systane Complete after my cataract surgery, and it burned the inside of my nose and gave me symptoms of hay fever with lots of sneezing. Horrible product and should be taken off the market. I suspect that it's the preservative in Systane that is the culprit."

1 / 10
Was this helpful?YesNo
2 Report
  • Anonymous
  • Taken for 2 to 5 years
  • December 10, 2022

"I don't have a problem with the eye drops, they work fine for me. My problem is the bottle: after I use it only a few times, the liquid will not come out anymore. I shake it and hear it, so there's still a full bottle, it just will not come out. I throw the bottle away and open a new one. Sometimes it works, and sometimes it doesn't. It's a waste of my money to keep buying, but I really like the Systane. I don't want to start another brand, so what do I do?"

10 / 10
Was this helpful?YesNo
1 Report
  • No ...
  • June 9, 2020

"Have lost most of my lashes from Systane."

1 / 10
Was this helpful?YesNo
21 Report
  • Anonymous
  • Taken for 1 to 6 months
  • March 1, 2023

"Toxic product. I was prescribed these eye drops. They cause calcific eyelid discharge, increased sensitivity to light, stinging, and pain, and they seem to offer no improvement."

1 / 10
Was this helpful?YesNo
10 Report
  • She...
  • Taken for less than 1 month
  • April 4, 2020

"I started Systane Complete on March 31. Have had a bad taste in mouth and burning since. Going to try different drops."

1 / 10
Was this helpful?YesNo
18 Report
  • Mar...
  • Taken for 1 to 2 years
  • May 19, 2019

"I have used the Systane Complete for two years, and the side effects are I lost all my lashes and have a cyst in my left eye, all due to the drops. I will never use it again!"

1 / 10
Was this helpful?YesNo
20 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

Learn more about Dry Eye Disease

Care guides

Symptoms and treatments

Medicine.com guides (external)