Symproic and Diarrhea: What Users Say

• gym...
• Taken for less than 1 month
• September 14, 2020

For Opioid-Induced Constipation "Symproic has not worked well for me. My insurance company forced me to try it prior to them approving Movantik or Amitiza, and I have never felt this sick or uncomfortable. I assume this is what mild opiate withdrawal feels like. I contacted my doctor to see if nausea, sweats/chills, cramps, diarrhea, and agitation were common side effects. If the point of Symproic is just to send you into withdrawal to induce a bowel movement (which is just severe diarrhea at this point), I guess it works. I could have just gone cold turkey on my pain medications if I wanted to do that."

• Pam...
• February 16, 2020

For Opioid-Induced Constipation "I started taking this three days ago. I tried Movantik a while back, and every time it made me nauseous, and ultimately I would vomit. I did poop, however. The first couple of days I took Symproic, it worked like a charm. On the third day, I did get some cramping and diarrhea, but since I’d barely gone in two weeks, I figured I needed a good cleansing! So, keeping in mind it’s only been three days, I highly recommend. I’ll post again after I’ve used it a while. Good luck!"

• Not...
• January 18, 2018

For Opioid-Induced Constipation "I had eaten a high-fat small meal prior to taking for the first time - within an hour of taking the SYMPROIC 0.2 mg tablet, I began to feel nauseated, which was escalating - I was on the verge of vomiting for another 20-30 minutes & had begun having quite intense abdominal cramping & pain with sudden intense frequent diarrhea & sweating & significant dizziness & fatigue - I continued to have intense nausea & abdominal pain & dizziness & I could barely keep my eyes open & then sweats & chills. I then vomited intensely 2 times & had 2 more episodes of watery diarrhea & was still dizzy & very fatigued. I have had a headache & experienced some episodes of a heaviness in my chest & vomiting & diarrhea have ceased. I had a significant BAD reaction."

• Mom...
• Taken for 1 to 2 years
• May 24, 2023

For Opioid-Induced Constipation "Was taking Movantik for a while and was still constipated for years when my pain management physician asked me to try Symproic a year and a half ago. It began working right away without any side effects; however, after taking it for a year, I began having short bouts of diarrhea, constant nausea, and bilateral flank pain. Last summer, the diarrhea was frequent and at certain times very painful, lasting for days. Then I started feeling sick, and these episodes started occurring every few days. Just recently, I realized maybe Symproic was the cause. I stopped it and went back to Movantik four weeks ago. Since stopping Symproic, I haven't had any diarrhea. But the downside is now I'm constipated again. The Symproic worked well for my constipation for many months, great, then all the side effects started and are just too hard on my body. Is there something else that works for opioid-induced constipation?"

• Ray...
• Taken for 6 months to 1 year
• August 21, 2022

For Opioid-Induced Constipation "Only medication that works. Yes, I get stomach cramps, but going to the bathroom far outweighs the pain. Highly recommend. 0.2 mg is what I take with my hydrocodone. Sometimes I get diarrhea, then I take it only once a day instead of three times a day. Most of the time, once a day is all that is required. The advantages far outweigh the side effects."

• Cha...
• Taken for 2 to 5 years
• June 2, 2024

For Opioid-Induced Constipation "Symproic has been amazing for me. I only take it as needed because, for me, it’s an all-day event. So I can’t take it when I’m working, otherwise, I would be in the bathroom all day. Towards the end, I get diarrhea, but it’s not bad. I would suggest for those working, try it on a weekend first when you’re close to the bathroom just in case your response is like mine. I occasionally have pretty severe stomach cramps when taking it, but it’s manageable. It takes about two hours to start working."