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Is Symproic a controlled substance?

Medically reviewed by Last updated on Oct 28, 2020.

Official Answer


No, Symproic (naldemedine) is not a controlled substance.

In September 2017, naldemedine was reclassified by the DEA removing it from classification as a schedule II narcotic (a drug that can be abused or lead to drug-seeking behavior and addiction) to no schedule.

Symproic is an oral medication used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain. Keep this medicine in a safe place to prevent misuse and abuse.

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